Section edited by Hemant Khanna and Javier Zarranz-Ventura

This section considers articles on all aspects of the prevention, diagnosis and management of retinal diseases as well as related molecular and cellular biology, genetics and pathophysiology. The section particularly welcomes prospective clinical studies, especially randomized controlled trials.

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  1. Case report

    A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy

    To report the case of a patient with pseudoxanthoma elasticum (PXE) and proliferative diabetic retinopathy (PDR), and discuss the relationship between PXE and diabetic retinopathy (DR).

    Keigo Kakurai, Maiko Hayashi, Kanako Yamada, Norihiko Ishizaki, Yumiko Yonemoto, Seita Morishita, Ryohsuke Kohmoto, Takaki Sato, Teruyo Kida and Tsunehiko Ikeda

    BMC Ophthalmology 2017 17:184

    Published on: 4 October 2017

  2. Research article

    Quantitative evaluation of hard exudates in diabetic macular edema after short-term intravitreal triamcinolone, dexamethasone implant or bevacizumab injections

    To quantitatively compare short-term hard exudates (HEs) alteration in patients with diabetic macular edema (DME) after intravitreal triamcinolone, dexamethasone implant or bevacizumab injections.

    Yong Un Shin, Eun Hee Hong, Han Woong Lim, Min Ho Kang, Mincheol Seong and Heeyoon Cho

    BMC Ophthalmology 2017 17:182

    Published on: 3 October 2017

  3. Research article

    Development and validation of a questionnaire assessing the quality of life impact of Colour Blindness (CBQoL)

    Congenital colour vision deficiency (CVD), commonly called ‘colour blindness’, affects around 8% of men and 0.4% of women. Although many aspects of health (e.g. change in colour of urine) and healthcare (e.g. ...

    John A. Barry, Susan Mollan, Michael A. Burdon, Michelle Jenkins and Alastair K. Denniston

    BMC Ophthalmology 2017 17:179

    Published on: 2 October 2017

  4. Research article

    Semi-automated quantification of hard exudates in colour fundus photographs diagnosed with diabetic retinopathy

    Hard exudates (HEs) are the classical sign of diabetic retinopathy (DR) which is one of the leading causes of blindness, especially in developing countries. Accordingly, disease screening involves examining HE...

    Abhilash Goud Marupally, Kiran Kumar Vupparaboina, Hari Kumar Peguda, Ashutosh Richhariya, Soumya Jana and Jay Chhablani

    BMC Ophthalmology 2017 17:172

    Published on: 20 September 2017

  5. Research article

    Internal limiting membrane peeling and gas tamponade for myopic foveoschisis: a systematic review and meta-analysis

    Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment op...

    Bo Meng, Lu Zhao, Yi Yin, Hongyang Li, Xiaolei Wang, Xiufen Yang, Ran You, Jialin Wang, Youjing Zhang, Hui Wang, Ran Du, Ningli Wang, Siyan Zhan and Yanling Wang

    BMC Ophthalmology 2017 17:166

    Published on: 8 September 2017

  6. Technical advance

    Apln-CreERT:mT/mG reporter mice as a tool for sprouting angiogenesis study

    Angiogenesis is defined as a new blood vessel sprouting from pre-existing vessels, and the sprouting angiogenesis is the start phase of angiogenesis, which is critical for both physiological and pathological p...

    Jingjiang Pi, Yu Cheng, Huimin Sun, Xiaoli Chen, Tao Zhuang, Jie Liu, Yixi Li, Huan Chang, Lin Zhang, YuZhen Zhang and Ting Tao

    BMC Ophthalmology 2017 17:163

    Published on: 2 September 2017

  7. Research article

    Absolute and estimated values of macular pigment optical density in young and aged Asian participants with or without age-related macular degeneration

    Lutein and zeaxanthin are suggested micronutrient supplements to prevent the progression of age-related macular degeneration (AMD), a leading cause of blindness worldwide. To monitor the levels of lutein/zeaxa...

    Yoko Ozawa, Yuta Shigeno, Norihiro Nagai, Misa Suzuki, Toshihide Kurihara, Sakiko Minami, Eri Hirano, Hajime Shinoda, Saori Kobayashi and Kazuo Tsubota

    BMC Ophthalmology 2017 17:161

    Published on: 29 August 2017

  8. Research article

    Applying next generation sequencing with microdroplet PCR to determine the disease-causing mutations in retinal dystrophies

    Inherited Retinal dystrophy (IRD) is a broad group of inherited retinal disorders with heterogeneous genotypes and phenotypes. Next generation sequencing (NGS) methods have been broadly applied for analyzing p...

    Xinjing Wang, Wadih M. Zein, Leera D’Souza, Chimere Roberson, Keith Wetherby, Hong He, Angela Villarta, Amy Turriff, Kory R. Johnson and Yang C. Fann

    BMC Ophthalmology 2017 17:157

    Published on: 24 August 2017

  9. Research article

    Visual function improvement using photocromic and selective blue-violet light filtering spectacle lenses in patients affected by retinal diseases

    To evaluate functional visual parameters using photocromic and selective blue-violet light filtering spectacle lenses in patients affected by central or peripheral scotoma due to retinal diseases.

    L. Colombo, E. Melardi, P. Ferri, G. Montesano, S. Samir Attaalla, F. Patelli, S. De Cillà, G. Savaresi and L. Rossetti

    BMC Ophthalmology 2017 17:149

    Published on: 22 August 2017

  10. Research article

    Predictive models of long-term anatomic outcome in age-related macular degeneration treated with as-needed Ranibizumab

    To analyze predictors and develop predictive models of anatomic outcome in neovascular age-related macular degeneration (AMD) treated with as-needed ranibizumab after 4 years of follow-up.

    Lucia Gonzalez-Buendia, Santiago Delgado-Tirado, M. Rosa Sanabria, Itziar Fernandez and Rosa M. Coco

    BMC Ophthalmology 2017 17:147

    Published on: 18 August 2017

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