Section edited by Hemant Khanna and Javier Zarranz-Ventura

This section considers articles on all aspects of the prevention, diagnosis and management of retinal diseases as well as related molecular and cellular biology, genetics and pathophysiology. The section particularly welcomes prospective clinical studies, especially randomized controlled trials.

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  1. Case report

    Intraoperative optical coherence tomography assisted analysis of pars Plana vitrectomy for retinal detachment in morning glory syndrome: a case report

    The pathogenesis of non-rhegmatogenous retinal detachment (non-RRD) associated with morning glory syndrome (MGS) is not established, as well as best surgical approach to treat RD. Our purpose was to analyse in...

    Lyubomyr M. Lytvynchuk, Carl G. Glittenberg, Siamak Ansari-Shahrezaei and Susanne Binder

    BMC Ophthalmology 2017 17:134

    Published on: 1 August 2017

  2. Research article

    Lutein and zeaxanthin isomers modulates lipid metabolism and the inflammatory state of retina in obesity-induced high-fat diet rodent model

    Several studies associated high-fat intakes with a high incidence of age-related macular degeneration (AMD). Lutein and Zeaxanthin isomers (L/Zi) may counteract reactive oxygen species produced by oxidative st...

    Mehmet Tuzcu, Cemal Orhan, Omer Ersin Muz, Nurhan Sahin, Vijaya Juturu and Kazım Sahin

    BMC Ophthalmology 2017 17:129

    Published on: 24 July 2017

  3. Research article

    Tracing the natural course of visual acuity and quality of life in neovascular age-related macular degeneration: a systematic review and quality of life study

    Describing the natural course of neovascular age-related macular degeneration (nAMD) is essential in discussing prognosis and treatment options with patients and to support cost-effectiveness studies.

    Mari Elshout, Carroll A. Webers, Margriet I. van der Reis, Yvonne de Jong-Hesse and Jan S. Schouten

    BMC Ophthalmology 2017 17:120

    Published on: 11 July 2017

  4. Research article

    Short-term efficacy of intravitreal Aflibercept injections for retinal angiomatous proliferation

    To evaluate the short-term efficacy of intravitreal injections of aflibercept (IVA) to treat retinal angiomatous proliferation (RAP) and identify factors related to functional outcomes.

    Hung-Da Chou, Wei-Chi Wu, Nan-Kai Wang, Lan-Hsin Chuang, Kuan-Jen Chen and Chi-Chun Lai

    BMC Ophthalmology 2017 17:104

    Published on: 27 June 2017

    The Erratum to this article has been published in BMC Ophthalmology 2017 17:144

  5. Research article

    Association between polymorphism rs11200638 in the HTRA1 gene and the response to anti-VEGF treatment of exudative AMD: a meta-analysis

    Anti-angiogenesis treatments are the most commonly used treatments for the vision loss caused by exudative age-related macular degeneration (AMD), in which the anti-vascular endothelial growth factor (VEGF) dr...

    Ya-li Zhou, Chun-li Chen, Yi-xiao Wang, Yao Tong, Xiao-ling Fang, Lin Li and Zhao-yang Wang

    BMC Ophthalmology 2017 17:97

    Published on: 21 June 2017

  6. Research article

    Correlation of retinal nerve fibre layer and macular thickness with serum uric acid among type 2 diabetes mellitus

    Uric acid is a final breakdown product of purine catabolism in humans. It’s a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascular endothelial cells, thus mediatin...

    Munisamy-Naidu Vinuthinee-Naidu, Embong Zunaina, Anuar Azreen-Redzal and Naing Nyi-Nyi

    BMC Ophthalmology 2017 17:91

    Published on: 14 June 2017

  7. Research article

    Correlation between short- and long-term effects of intravitreal ranibizumab therapy on macular edema after branch retinal vein occlusion: a prospective observational study

    The correlation between the short- and long-term effects of intravitreal ranibizumab (IVR) on macular edema after branch retinal vein occlusion (BRVO) remains unclear. We assessed the correlation between the s...

    Yoshiro Minami, Taiji Nagaoka, Akihiro Ishibazawa and Akitoshi Yoshida

    BMC Ophthalmology 2017 17:90

    Published on: 13 June 2017

  8. Research article

    Serum uric acid concentration is associated with hypertensive retinopathy in hypertensive chinese adults

    This cross sectional investigation included 12,966 subjects with hypertension, a cohort of the China Stroke Primary Prevention Trial (CSPPT), a randomized, multicenter clinical trial. This study aimed to explore ...

    Xuling Chen, Ying Meng, Jun Li, Hiacheng She, Liang Zhao, Jing Zhang, Yuan Peng, Kun Shang, Yadi Zhang, Xiaopeng Gu, Wenbin Yang, Yan Zhang, Jianping Li, Xianhui Qin, Binyan Wang, Xiping Xu…

    BMC Ophthalmology 2017 17:83

    Published on: 2 June 2017

  9. Research article

    Switch to aflibercept or ranibizumab after initial treatment with bevacizumab in eyes with neovascular AMD

    To evaluate changes in central macular thickness (CMT) and visual outcome in patients with neovascular age-related macular degeneration (AMD) treated initially with bevacizumab and subsequently switched to eit...

    Maria Waizel, Margarita G. Todorova, Michael Masyk, Katharina Wolf, Annekatrin Rickmann, Khaled Helaiwa, Björn R. Blanke and Peter Szurman

    BMC Ophthalmology 2017 17:79

    Published on: 23 May 2017

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