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Retina

This section considers articles on all aspects of the prevention, diagnosis and management of retinal diseases as well as related molecular and cellular biology, genetics and pathophysiology. The section particularly welcomes prospective clinical studies, especially randomized controlled trials.

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  1. To evaluate the correlation between visual acuity improvement and vision-related QOL after ranibizumab treatment in Japanese patients with AMD.

    Authors: Yuji Oshima, Yumi Ishibashi, Naoyasu Umeda, Tatsuo Nagata, Shigeo Yoshida, Eiichi Uchio, Hiroyuki Kondo, Koh-hei Sonoda and Tatsuro Ishibashi

    Citation: BMC Ophthalmology 2021 21:58

    Content type: Research article

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  2. Sturge-Weber syndrome is a disorder marked by a distinctive facial capillary malformation, neurological abnormalities, and ocular abnormalities such as glaucoma and choroidal hemangioma.

    Authors: Zhengping Hu, Jian Cao, Eun Young Choi and Yun Li

    Citation: BMC Ophthalmology 2021 21:56

    Content type: Research article

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  3. The supply of Cilioretinal artery (CRA) to different layers of the retina influences retinal pathologies such as diabetic retinopathy (DR). Since the supply of CRA is segmental, our aim was to analyze the loca...

    Authors: Rehana Khan, Mahesh Shanmugam, Rajesh Ramanjulu, Jay Chablani, Niharika Singh, Avadhesh Oli and Rajiv Raman

    Citation: BMC Ophthalmology 2021 21:51

    Content type: Research article

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  4. Tears in Schwartz-Matsuo syndrome are generally confirmed by preoperative ophthalmoscopic examination. A case of Schwartz-Matsuo syndrome with a tear detected by ultrasound biomicroscopy (UBM) and treated by U...

    Authors: Yao Wang, Zhongli Hu, Yifan Jiang, Huan Liu and Xiaoyun Fang

    Citation: BMC Ophthalmology 2021 21:49

    Content type: Case report

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  5. To present a case report of a patient with a mixed choroidal neovascular membrane (CNV) with an asymmetric response to ranibizumab diagnosed on optical coherence tomography angiography (OCTa).

    Authors: Martin Pencak and Miroslav Veith

    Citation: BMC Ophthalmology 2021 21:42

    Content type: Case report

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  6. To investigate the effect of intravitreal dexamethasone implant (DEX implant) on hard exudate (HE) accompanying diabetic macular edema (DME).

    Authors: Chang Ki Yoon, Min Sagong, Jae Pil Shin, Sang Joon Lee, Joo Eun Lee, Ji Eun Lee, Inyoung Chung, Woo Jin Jeong, Kang Yeun Pak and Hyun Woong Kim

    Citation: BMC Ophthalmology 2021 21:41

    Content type: Research article

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  7. Retinitis Pigmentosa (RP) is the most frequent retinal hereditary disease and every kind of transmission pattern has been described. The genetic etiology of RP is extremely heterogeneous and in the last few ye...

    Authors: Marcella Nebbioso, Federica Franzone, Alessandro Lambiase, Maurizio La Cava, Fabiana Mallone, Antonio Pizzuti and Enrica Marchionni

    Citation: BMC Ophthalmology 2021 21:37

    Content type: Case report

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  8. Macular edema secondary to retinal vein occlusion (RVO) is an important cause of loss of vision. Intravitreal injections (IVI) of anti-vascular endothelial growth factor (VEGF) are the standard of care in this...

    Authors: Raja Narayanan, Aditya Kelkar, Zahir Abbas, Neha Goel, Manoj Soman, Naveen Naik, Aditya Sudhalkar, Jaydeep Walinjkar, Utkarsh Shah and Nitin Maksane

    Citation: BMC Ophthalmology 2021 21:33

    Content type: Research article

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  9. Central serous chorioretinopathy (CSC) is characterized by an accumulation of subretinal fluid (SRF) in the macula. It is usually treated by laser photocoagulation or photodynamic therapy (PDT) with consisting...

    Authors: Jirarattanasopa Pichai, Banchasakjaroen Vanchalerm and Ratanasukon Mansing

    Citation: BMC Ophthalmology 2021 21:30

    Content type: Research article

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  10. However there have been numerous investigations of intrascleral intraocular lens (IOL) fixation techniques, there is room for improvement in terms of simplifying complicated techniques and reducing the high le...

    Authors: Tatsuya Jujo, Jiro Kogo, Hiroki Sasaki, Reio Sekine, Keiji Sato, Sakura Ebisutani, Yasuhiro Toyoda, Yasushi Kitaoka and Hitoshi Takagi

    Citation: BMC Ophthalmology 2021 21:8

    Content type: Research article

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  11. To study the enlargement rate of primary geographic atrophy (GA) before and after diagnosis of a secondary choroidal neovascularization (CNV) treated with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Jakob Siedlecki, Caroline Koch, Benedikt Schworm, Raffael Liegl, Thomas Kreutzer, Karsten U. Kortuem, Ricarda Schumann, Siegfried G. Priglinger and Armin Wolf

    Citation: BMC Ophthalmology 2021 21:4

    Content type: Research article

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  12. The purpose of the study was to explore the immunological components that are responsible for the proliferative alterations in the different forms of retinal detachment (RD).

    Authors: Anikó Balogh, Tibor Milibák, Viktória Szabó, Zoltán Zsolt Nagy, Kai Kaarniranta and Miklós D. Resch

    Citation: BMC Ophthalmology 2020 20:491

    Content type: Research article

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  13. Usher syndrome is a disease with a heterogeneous phenotype and genotype. Our purpose was to identify the gene mutation in a Chinese family with Usher syndrome type 2 and describe the clinical features.

    Authors: Dongjun Xing, Huaiyu Zhou, Rongguo Yu, Linni Wang, Liying Hu, Zhiqing Li and Xiaorong Li

    Citation: BMC Ophthalmology 2020 20:485

    Content type: Case report

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  14. Choroidal neovascularization (CNV) in pregnancy has rarely been described. A differential diagnosis between inflammatory, idiopathic, and myopic CNV may be challenging. Moreover, there is no consensus on manag...

    Authors: Emilia Maggio, Maurizio Mete, Antonio Polito, Gloria Parrozzani and Grazia Pertile

    Citation: BMC Ophthalmology 2020 20:483

    Content type: Case report

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  15. Ocular involvement in catastrophic antiphospholipid syndrome (CAPS), a rare, life-threatening form of antiphospholipid syndrome (APS) that results in multiorgan failure and a high mortality rate, has rarely be...

    Authors: Young In Yun, Ji Hyun Kim, Seon Hee Lim, Yo Han Ahn, Hee Gyung Kang, Il-Soo Ha and Baek-Lok Oh

    Citation: BMC Ophthalmology 2020 20:482

    Content type: Case report

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  16. To report undescribed characteristics of patients with bilateral diffuse uveal melanocytic proliferation (BDUMP) on ultrasound biomicroscopy (UBM) and high-frequency B-scan ultrasonography.

    Authors: Jingli Guo, Wenyi Tang, Wei Liu, Min Zhou, Qing Chang, Chunhui Jiang, Gezhi Xu, Wenji Wang and Qian Chen

    Citation: BMC Ophthalmology 2020 20:476

    Content type: Case report

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  17. Offspring of parent(s) with age-related macular degeneration (AMD) have a 45% lifetime risk of developing the disease. High foveal macular pigment optical density (MPOD) is protective, whereas individuals with...

    Authors: Grant A. Rutledge, Steven G. Pratt, Stuart P. Richer, Byki Huntjens, C. Blake Perry, Gunilla Pratt and Carla Podella

    Citation: BMC Ophthalmology 2020 20:473

    Content type: Research article

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  18. To analyze the distribution of manifest lesions of diabetic retinopathy (DR) by fundus fluorescein angiography (FFA) and color fundus photography (FP).

    Authors: Xiaoli Li, Jie Xie, Liang Zhang, Ying Cui, Guanrong Zhang, Jun Wang, Aiping Zhang, Xiangting Chen, Tian Huang and Qianli Meng

    Citation: BMC Ophthalmology 2020 20:471

    Content type: Research article

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  19. To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient.

    Authors: Pierre-Guillaume Deliège, Justine Bastien, Laetitia Mokri, Charlotte Guyot-Colosio, Carl Arndt and Philippe Rieu

    Citation: BMC Ophthalmology 2020 20:468

    Content type: Case report

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  20. Diabetic retinopathy (DR) is a serious microvascular complication of type 2 diabetes mellitus (T2DM). The aim of this retrospective study was to reveal the risk factors for the severity of DR in individuals wi...

    Authors: Donghe Chen, Xiufang Sun, Xinxin Zhao and Ying Liu

    Citation: BMC Ophthalmology 2020 20:467

    Content type: Research article

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  21. The current National Health Insurance scheme in Taiwan reimburses 3 initial plus 4 additional injections of ranibizumab 0.5 mg for eligible patients with neovascular age-related macular degeneration (nAMD). Th...

    Authors: Wen-Chuan Wu, Jiann-Torng Chen, Ching-Yao Tsai, Chien-Liang Wu, Cheng-Kuo Cheng, Yun-Dun Shen, Arslan Tsai and Pei-Chang Wu

    Citation: BMC Ophthalmology 2020 20:462

    Content type: Research article

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  22. Routine eye examination plays a vital role in detecting diabetic retinopathy in its earliest stage before the onset of blindness. Patients’ knowledge about the nature and the consequences of diabetic retinopat...

    Authors: Abel Sinshaw Assem, Mebratu Mulusew Tegegne, Destaye Shiferaw Alemu, Asamere Tsegaw Woredekal and Tsehay Kassa Tefera

    Citation: BMC Ophthalmology 2020 20:453

    Content type: Research article

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  23. To identify different response patterns to intravitreal dexamethasone implants (IDI) in naïve and previously treated (PT) diabetic macular edema (DME) eyes in a real-life setting.

    Authors: Javier Zarranz-Ventura, Barbara Romero-Núñez, Carolina Bernal-Morales, Daniel Velazquez-Villoria, Anna Sala-Puigdollers, Marc Figueras-Roca, Sergio Copete, Laura Distefano, Anna Boixadera, Jose García-Arumi and Alfredo Adan

    Citation: BMC Ophthalmology 2020 20:443

    Content type: Research article

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  24. Numerous cytokines have been proven to participate in the pathogenesis of neovascular age-related macular degeneration (nAMD). The present study aimed to investigate the aqueous humor cytokine expression profi...

    Authors: Kailin Chen, Wen Xu, Jiao Zheng, Yupeng Shen, Jian Ma and Zhiqing Chen

    Citation: BMC Ophthalmology 2020 20:431

    Content type: Research article

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  25. Perfluorocarbon liquid (PFCL) is an effective surgical adjuvant in performing vitrectomy for severe vitreoretinal pathologies such as proliferative vitreoretinopathy and giant retinal tears. However, subretina...

    Authors: Kosuke Takahashi, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Shinichiro Doi, Ryo Matoba, Yuki Kanzaki, Yoshihiro Yonekawa and Yuki Morizane

    Citation: BMC Ophthalmology 2020 20:427

    Content type: Case report

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  26. Neurofibromatosis type 1 (NF1) is a hereditary disease that causes neurofibromas generally, but it has been reported to sometimes be associated with various forms of blood vessel stenosis, occlusion and vascul...

    Authors: Hiroaki Sakai, Kosuke Kawata, Jun Masuoka, Tomohisa Nishimura and Hiroshi Enaida

    Citation: BMC Ophthalmology 2020 20:426

    Content type: Case report

    Published on:

  27. To prevent irreversible vision loss in age-related macular degeneration (AMD), it is critical to detect retinal dysfunction before permanent structural loss occurs. In the current study we evaluated a series o...

    Authors: Divya Narayanan, John Rodriguez, Garrick Wallstrom, Donna Welch, Matthew Chapin, Paul Arrigg and Mark Abelson

    Citation: BMC Ophthalmology 2020 20:424

    Content type: Research article

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  28. To investigate the difference in retinal nerve fiber layer (RNFL) thickness, choroidal thickness (CT) and superficial retinal vessels between thyroid-associated ophthalmopathy (TAO) patients and healthy contro...

    Authors: Lanchu Yu, Qin Jiao, Yu Cheng, Yanji Zhu, Zhongjing Lin and Xi Shen

    Citation: BMC Ophthalmology 2020 20:421

    Content type: Research article

    Published on:

  29. Proliferative diabetic retinopathy (PDR) is one of the most common cause of vision loss in diabetic patients, and the incidence age of PDR patients gradually gets younger. This study aims to compare the charac...

    Authors: Mengyu Liao, Xiaohong Wang, Jinguo Yu, Xiangda Meng, Yuanyuan Liu, Xue Dong, Jianan Li, Rodrigo Brant, Bo Huang and Hua Yan

    Citation: BMC Ophthalmology 2020 20:416

    Content type: Research article

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  30. Whipple’s disease (WD) is a rare, chronic, infection caused by gram-positive filamentous aerobic actinobacterium Tropheryma whipplei occurs classically in the gastrointestinal tract and shows histopathological...

    Authors: Waleed K. Alsarhani, Muhannad I. Alkhalifah, Hind M. Alkatan, Afaf L. Alsolami, Azza M. Y. Maktabi and Adel H. Alsuhaibani

    Citation: BMC Ophthalmology 2020 20:413

    Content type: Case report

    Published on:

  31. Diabetic macular edema (DME) is the most common cause of vision loss in diabetic patients. As India has the second largest population of diabetic patients worldwide, availability of various treatment options f...

    Authors: Unnikrishnan Nair, Vishali Gupta, Mohita Sharma, Shrinivas Joshi, Aditya Sudhalkar, Undraa Altangerel and Yan Bai

    Citation: BMC Ophthalmology 2020 20:405

    Content type: Research article

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  32. We conducted this study to report on the indications and types of retinal laser therapy (RLT) performed in Bhutan, knowing which is critical for proper planning and successful delivery of the services.

    Authors: Bhim B. Rai, Michael G. Morley, Pema Zangmo, Thukten Tshering, Abi N. Khatiwara, Paul S. Bernstein and Ted Maddess

    Citation: BMC Ophthalmology 2020 20:404

    Content type: Research article

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  33. Optical coherence tomography angiography (OCTA) is a newly developed imaging quantitative technique for analysis of choriocapillaris (CC) flow changes, thereby exploring the pathological mechanism of chronic c...

    Authors: Juejun Liu, Changzheng Chen, Lu Li, Yishuang Xu, Zuohuizi Yi, Lu He and Hongmei Zheng

    Citation: BMC Ophthalmology 2020 20:402

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Ophthalmology 2020 20:445

  34. Here we report a case of traction retinal detachment (TRD) associated with congenital retinal vascular hypoplasia localized in the superotemporal quadrant that was treated with vitrectomy.

    Authors: Tomomi Miyamoto, Takatoshi Kobayashi, Teruyo Kida, Takaki Sato, Masanori Fukumoto and Tsunehiko Ikeda

    Citation: BMC Ophthalmology 2020 20:398

    Content type: Case report

    Published on:

  35. To investigate the clinical features of diabetic macular edema (DME) in eyes with pachychoroid phenotypes using multimodal retinal imaging.

    Authors: Kyungeun Kang, Hyungwoo Lee, Minsu Jang, Hyung Chan Kim and Hyewon Chung

    Citation: BMC Ophthalmology 2020 20:392

    Content type: Research article

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  36. Age-related macular degeneration (AMD) is a chronic eye condition that leads to permanent vision loss in the central visual field. AMD makes reading challenging and inefficient. People with AMD often find it d...

    Authors: Jennifer Fortuna, Anne Riddering, Linda Shuster and Cassie Lopez-Jeng

    Citation: BMC Ophthalmology 2020 20:391

    Content type: Research article

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  37. To report a rare case of pathologic myopia in which a choroidal neovascularization (CNV) induced a hemorrhagic macular hole retinal detachment (MHRD), and then both the CNV and MHRD disappeared simultaneously ...

    Authors: Taiju Ito, Tae Igarashi-Yokoi, Kosei Shinohara, Takeshi Yoshida and Kyoko Ohno-Matsui

    Citation: BMC Ophthalmology 2020 20:385

    Content type: Case report

    Published on:

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