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Retina

This section considers articles on all aspects of the prevention, diagnosis and management of retinal diseases as well as related molecular and cellular biology, genetics and pathophysiology. The section particularly welcomes prospective clinical studies, especially randomized controlled trials.

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  1. The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymo...

    Authors: Ine Lambert, Giuseppe Fasolino, Gil Awada, Robert Kuijpers, Marcel ten Tusscher and Bart Neyns

    Citation: BMC Ophthalmology 2021 21:250

    Content type: Case report

    Published on:

  2. Choroidal osteoma is a benign intraocular tumor that can increase risk of developing choroidal neovascularization. The visual prognosis is influenced by the tumor location, decalcification status, overlying RP...

    Authors: Yun Zhang, Jia Fang, Shixin Zhao, Xiangjun She, Jun Wang and Lijun Shen

    Citation: BMC Ophthalmology 2021 21:242

    Content type: Case report

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  3. Myotonic dystrophy is an inherited disease characterized by progressive muscle weakness and myotonia. It is a multisystemic disorder that affects different parts of the body, including the eye. Dysfunction of ...

    Authors: Eric Kirkegaard-Biosca, Mònica Berges-Marti, Brahim Azarfane, Esther Cilveti, Laura Distefano and Jose García-Arumí

    Citation: BMC Ophthalmology 2021 21:240

    Content type: Case report

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  4. Bietti crystalline dystrophy (BCD) is an autosomal recessive genetic disorder that causes progressive vision loss. Here, 12 patients were followed up for 1–5 years with fundus fluorescein angiography (FFA) to ...

    Authors: Shengjuan Zhang, Lifei Wang, Zhiqiang Liu, Huijing Sun, Qian Li, Chen Xing, Zhe Xiao and Xiaoyan Peng

    Citation: BMC Ophthalmology 2021 21:239

    Content type: Research article

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  5. Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we e...

    Authors: William Greig Mitchell, Edward Christopher Dee and Leo Anthony Celi

    Citation: BMC Ophthalmology 2021 21:228

    Content type: Correspondence

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  6. To investigate the changes in retinal nerve fiber layer thickness and macular blood flow density during the preclinical stage of diabetic retinopathy and their relationship with blood glucose.

    Authors: Hui Li, Xiaobing Yu, Bodi Zheng, Shan Ding, Zhongqing Mu and Lixin Guo

    Citation: BMC Ophthalmology 2021 21:220

    Content type: Research article

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  7. Insulin positively correlates with the length of the eye axis and is increased in the vitreous and serum of patients with pathological myopia (PM). How insulin influences the physiological process of retinal p...

    Authors: Yunqin Li, Junliang Jiang, Jin Yang, Libo Xiao, Qiyun Hua and Yue Zou

    Citation: BMC Ophthalmology 2021 21:218

    Content type: Research article

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  8. A reliable and effective method is required to deliver agent that can aid the in vivo imaging of retinal vessels. The aim of the present study was to evaluate retro-orbital (RO) injection of fluorescein-labele...

    Authors: Jizhu Li, Yuqing Wu, Bingqian Liu, Ying Huang, Qingxiu Wu, Haichun Li, Sainan Xiao, Ying Lin and Tao Li

    Citation: BMC Ophthalmology 2021 21:208

    Content type: Research article

    Published on:

  9. COVID-19, a highly contagious respiratory virus, presents unique challenges to ophthalmology practice as a high-volume, office-based specialty. In response to the COVID-19 pandemic, many operational changes we...

    Authors: Karan Sethi, Emily S. Levine, Shiyoung Roh, Jeffrey L. Marx and David J. Ramsey

    Citation: BMC Ophthalmology 2021 21:206

    Content type: Research article

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  10. Berger’s IgA nephropathy (IgAN) is the most common primary glomerulonephritis. However, some rare cases of retinal manifestations have been described, with only two cases of retinal vasculopathy reported in th...

    Authors: Khaled El Matri, Francesca Amoroso, Olivia Zambrowski, Alexandra Miere and Eric H. Souied

    Citation: BMC Ophthalmology 2021 21:204

    Content type: Case report

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  11. Numerous cases with ocular toxicity secondary to tamoxifen have been reported, and became more apparent with keratopathy, cataract, optic neuritis, macular holes, crystalline retinopathy with or without cystoi...

    Authors: Chuanyu Li, Jun Xiao, He Zou, Bo Yang and Lifu Luo

    Citation: BMC Ophthalmology 2021 21:201

    Content type: Case report

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  12. During panretinal photocoagulation (PRP), the outer retina, especially the photoreceptors, are destroyed. During such procedures, the impact of the retinal photocoagulation, which is performed in the same phot...

    Authors: Kentaro Nishida, Shizuka Takahashi, Hirokazu Sakaguchi, Shigeru Sato, Masanori Kanai, Akihiko Shiraki, Taku Wakabayashi, Chikako Hara, Yoko Fukushima, Susumu Sakimoto, Kaori Sayanagi, Ryo Kawasaki and Kohji Nishida

    Citation: BMC Ophthalmology 2021 21:200

    Content type: Research article

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  13. To compare parsplana vitrectomy (PPV) with and without phacoemulsification to treat rhegmatogenous retinal detachment (RRD).

    Authors: Paolo Mora, Stefania Favilla, Giacomo Calzetti, Giulia Berselli, Lucia Benatti, Arturo Carta, Stefano Gandolfi and Salvatore A. Tedesco

    Citation: BMC Ophthalmology 2021 21:196

    Content type: Research article

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  14. To investigate alterations in retinal microvasculature in eyes with preclinical diabetic retinopathy (DR) using ultra-wide field swept-source optical coherence tomography angiography (UWF SS OCTA).

    Authors: Jingyuan Yang, Bilei Zhang, Erqian Wang, Song Xia and Youxin Chen

    Citation: BMC Ophthalmology 2021 21:192

    Content type: Research article

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  15. Myopic shift and biometric ocular changes have been previously observed after scleral buckling (SB) surgery in rhegmatogenous retinal detachment (RRD), but long term-term outcomes had not yet been explored. Th...

    Authors: Giuseppe Maria Albanese, Alberto Cerini, Giacomo Visioli, Marco Marenco and Magda Gharbiya

    Citation: BMC Ophthalmology 2021 21:172

    Content type: Research article

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  16. We present 3 members of a family with macular dystrophy, originally diagnosed as Stargardt disease, with a significantly variable age at onset, caused by a heterozygous mutation in CRX.

    Authors: Saoud Al-Khuzaei, Karl A. Z. Hudspith, Suzanne Broadgate, Morag E. Shanks, Penny Clouston, Andrea H. Németh, Stephanie Halford and Susan M. Downes

    Citation: BMC Ophthalmology 2021 21:168

    Content type: Case report

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  17. Pseudomyopia is caused by increased refractive power by ciliary muscle spasm. Most patients cannot overcome pseudomyopia spontaneously; therefore, treatment of pseudomyopia is fastidious and needs a multidisci...

    Authors: In Ki Park, Young Kee Park, Jae-Ho Shin and Yeoun Sook Chun

    Citation: BMC Ophthalmology 2021 21:159

    Content type: Case report

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  18. Pathogenic variants of G-protein coupled receptor 143 (GPR143) gene often leads to ocular albinism type I (OA1) characterized by nystagmus, iris and fundus hypopigmentation, and foveal hypoplasia. In this stud...

    Authors: Xiying Mao, Mingkang Chen, Yan Yu, Qinghuai Liu, Songtao Yuan and Wen Fan

    Citation: BMC Ophthalmology 2021 21:156

    Content type: Case report

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  19. Visual acuity is commonly used as a functional outcome measure in patients with age-related macular degeneration (AMD), despite having a weak correlation with self-perceived visual quality of life. Microperime...

    Authors: Thomas Richard Johansen Forshaw, Alexandra Kalia Parpounas and Torben Lykke Sørensen

    Citation: BMC Ophthalmology 2021 21:149

    Content type: Research article

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  20. As a novel high magnification module (HMM) combining with OCT (OCT-HMM) is able to detect the microstructure of retina, we apply it to explore the ultrastructure of the macula after closure of the idiopathic m...

    Authors: Chang-Yu Qiu, Yuan-Yuan Shi, Hong-Wei Zhao, Chuang Nie, Ming-Xia Dong, Huai-Qiang Zhang, Jun Zhao, Qian-Qian Xu, Fei-Long Song, Xiao-Hua Guo, Lin Shi, Chang-Ying Liu, Yu-Bo Gong and Ling Luo

    Citation: BMC Ophthalmology 2021 21:144

    Content type: Research article

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  21. Ultra-widefiled (UWF) retinal images include significant distortion when they are projected onto a two-dimensional surface for viewing. Therefore, many clinical studies that require quantitative analysis of fu...

    Authors: Su-Ho Lim, Seongyong Jeong, Jang Hwan Ahn, Jano van Hemert and Min Sagong

    Citation: BMC Ophthalmology 2021 21:141

    Content type: Research article

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  22. To evaluate the efficacy and outcomes of one-way surgical technique for the treatment of vitreous hemorrhage post vitrectomy on proliferative diabetic retinopathy (PDR) patients.

    Authors: Qun Wang, Jie Zhao, Qing Xu, Cui Han, Baojie Hou and Yifei Huang

    Citation: BMC Ophthalmology 2021 21:129

    Content type: Research article

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  23. This study aimed at investigating: 1) the relationship between self-care agency and depression and anxiety; 2) the sociodemographic and clinical factors associated with depression and anxiety in patients with ...

    Authors: Bo Zhang, Qin Wang, Xuancan Zhang, Li Jiang, Lezhi Li and Bangshan Liu

    Citation: BMC Ophthalmology 2021 21:123

    Content type: Research article

    Published on:

  24. Hyperoxia-mediated inhibition of vascular endothelial growth factor (VEGF) in the retina is the main cause of impeded angiogenesis during phase I retinopathy of prematurity (ROP). Human retinal angiogenesis in...

    Authors: Lan Jian, Yang Mei, Chen Xing and Yuan Rongdi

    Citation: BMC Ophthalmology 2021 21:104

    Content type: Research article

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  25. The natural course of a vortex vein varix, though not well understood, has been known to remain stable. However, here we report a novel case of a vortex vein varix that resolved after an extended period of mon...

    Authors: Sara L Weidmayer and Hakan Demirci

    Citation: BMC Ophthalmology 2021 21:101

    Content type: Case report

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  26. The prevalence of age-related macular degeneration (AMD) varies from 6.8 to 18.3% for all forms of AMD and from 0.6 to 2.6% for late AMD according to race, suggesting the existence of genetic differences among...

    Authors: Hyun-Tae Shin, Byung Woo Yoon and Je Hyun Seo

    Citation: BMC Ophthalmology 2021 21:97

    Content type: Research article

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  27. Polypoidal choroidal vasculopathy (PCV) is a type of age-related macular degeneration that can cause permanent vision loss. The purpose of this paper was to report the one-year outcomes of fixed-dosing afliber...

    Authors: Hun Gu Choo, Jin Hae Lee, Hyun Sub Oh, Soon Hyun Kim, Yong Sung You and Oh Woong Kwon

    Citation: BMC Ophthalmology 2021 21:94

    Content type: Research article

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  28. Anti–vascular endothelial growth factor (anti-VEGF) agents have become the standard of care in neovascular age-related macular degeneration (nAMD). Despite generally excellent response rates to anti-VEGF thera...

    Authors: Sam Razavi, Laurent Kodjikian, Audrey Giocanti-Aurégan, Ingrid Dufour and Eric Souied

    Citation: BMC Ophthalmology 2021 21:90

    Content type: Research article

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  29. Quantitative assessment of vascular density (VD) of retinal and choriocapillaris (CC) in various stages of diabetic retinopathy (DR) using spectral domain optical coherence tomography angiography (SD OCTA).

    Authors: Fariba Ghassemi, Kaveh Fadakar, Sahar Berijani, Ameneh Babeli, Alireza Gholizadeh and Siamak Sabour

    Citation: BMC Ophthalmology 2021 21:82

    Content type: Research article

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  30. Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to condu...

    Authors: Xujia Liu, Zehua Jiang, Guihua Zhang, Tsz Kin Ng and Zhenggen Wu

    Citation: BMC Ophthalmology 2021 21:81

    Content type: Research article

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  31. Using telemedicine for diabetic retinal screening is becoming popular especially amongst at-risk urban communities with poor access to care. The goal of the diabetic telemedicine project at Temple University H...

    Authors: James E. Benjamin, Justin Sun, Devin Cohen, Joseph Matz, Angela Barbera, Jeffrey Henderer, Lorrie Cheng, Julia Grachevskaya, Rajnikant Shah and Yi Zhang

    Citation: BMC Ophthalmology 2021 21:70

    Content type: Research article

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  32. To analyze multiple imaging modalities in patients with Bietti crystalline dystrophy (BCD) and to investigate which factors from these modalities are associated with best corrected visual acuity (BCVA).

    Authors: Chu-Yen Huang, Eugene Yu-Chuan Kang, Lung-Kun Yeh, An-Lun Wu, Pei-Kang Liu, I-Wen Huang, Joseph Ryu, Laura Liu, Wei-Chi Wu, Chi-Chun Lai, Kuan-Jen Chen and Nan-Kai Wang

    Citation: BMC Ophthalmology 2021 21:68

    Content type: Research article

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  33. Hemolytic Uremic Syndrome (HUS) is a rare disorder characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure, considered within the group of thrombocytic microa...

    Authors: David Pérez González, Matias Iglicki, Shuli Svetitsky, Yaeli Bar-On, Zohar Habot-Wilner and Dinah Zur

    Citation: BMC Ophthalmology 2021 21:65

    Content type: Case report

    Published on:

  34. To evaluate the correlation between visual acuity improvement and vision-related QOL after ranibizumab treatment in Japanese patients with AMD.

    Authors: Yuji Oshima, Yumi Ishibashi, Naoyasu Umeda, Tatsuo Nagata, Shigeo Yoshida, Eiichi Uchio, Hiroyuki Kondo, Koh-hei Sonoda and Tatsuro Ishibashi

    Citation: BMC Ophthalmology 2021 21:58

    Content type: Research article

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  35. Sturge-Weber syndrome is a disorder marked by a distinctive facial capillary malformation, neurological abnormalities, and ocular abnormalities such as glaucoma and choroidal hemangioma.

    Authors: Zhengping Hu, Jian Cao, Eun Young Choi and Yun Li

    Citation: BMC Ophthalmology 2021 21:56

    Content type: Research article

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  36. The supply of Cilioretinal artery (CRA) to different layers of the retina influences retinal pathologies such as diabetic retinopathy (DR). Since the supply of CRA is segmental, our aim was to analyze the loca...

    Authors: Rehana Khan, Mahesh Shanmugam, Rajesh Ramanjulu, Jay Chablani, Niharika Singh, Avadhesh Oli and Rajiv Raman

    Citation: BMC Ophthalmology 2021 21:51

    Content type: Research article

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  37. Tears in Schwartz-Matsuo syndrome are generally confirmed by preoperative ophthalmoscopic examination. A case of Schwartz-Matsuo syndrome with a tear detected by ultrasound biomicroscopy (UBM) and treated by U...

    Authors: Yao Wang, Zhongli Hu, Yifan Jiang, Huan Liu and Xiaoyun Fang

    Citation: BMC Ophthalmology 2021 21:49

    Content type: Case report

    Published on:

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Annual Journal Metrics

  • Speed
    82 days to first decision for reviewed manuscripts only
    60 days to first decision for all manuscripts
    200 days from submission to acceptance
    16 days from acceptance to publication

    Citation Impact
    1.413 - 2-year Impact Factor
    1.717 - 5-year Impact Factor
    0.949 - SNIP (Source-Normalized Impact per Paper)
    0.759 - SJR (SCImago Journal Rank)

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