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  1. To evaluate the relevance of external limiting membrane (ELM) on the visual and morphological results in eyes with diabetic macular edema (DME) that underwent pars plana vitrectomy (PPV) with epiretinal membra...

    Authors: Domagoj Ivastinovic, Anton Haas, Martin Weger, Gerald Seidel, Christoph Mayer-Xanthaki, Ewald Lindner, Andreas Guttmann and Andreas Wedrich
    Citation: BMC Ophthalmology 2021 21:334

    The Correction to this article has been published in BMC Ophthalmology 2021 21:380

  2. Plasma medicine is an innovative research field focused on the application of atmospheric-pressure low-temperature plasmas (ALTP) for therapeutic purposes. Considering the potentials of plasma in ophthalmology...

    Authors: Farhad Nejat, Khosrow Jadidi, Fahimeh Asadi Amoli, Shiva Bagheri, Hossein Aghamollaei, Mohammad-Amin Nejat, Nazanin-Sadat Nabavi and Shima Eghtedari
    Citation: BMC Ophthalmology 2021 21:333
  3. The present study sought to observe the effect of retaining intact posterior capsule in congenital cataract surgery in children aged 4–8 years.

    Authors: Jing Shang Zhang, Jin Da Wang, Mayinuer Yusufu, Kai Cao, Shan Shan Jin, Ying Xiong, Jing Li, Xiu Li Sun, Shu Ying Chen, Zhen Yu Liu, Jing Fu, Li Li, Qi Sheng You and Xiu Hua Wan
    Citation: BMC Ophthalmology 2021 21:332
  4. To evaluate macular microstructure alterations in the parafoveal nonperfusion areas of eyes with branch retinal vein occlusions (BRVO), and to investigate their impact on retinal sensitivity.

    Authors: Puying Wei, Chenchen Liu, Yanzhen Zhang and Liu Yang
    Citation: BMC Ophthalmology 2021 21:331
  5. To assess the effects of warm compress (WC) on tear film lipid layer, blink pattern and Meibomian gland function in patients with dry eye following femtosecond laser small incision lenticule extraction (SMILE)...

    Authors: Xueyi Zhou, Yang Shen, Jianmin Shang and Xingtao Zhou
    Citation: BMC Ophthalmology 2021 21:330
  6. To investigate the effects of small incision lenticule extraction (SMILE)-derived decellularized lenticules on intraocular pressure (IOP) and conjunctival scarring in a rabbit model of glaucoma filtration surg...

    Authors: Houfa Yin, Xinyi Chen, Xiaogang Hong, Jian Ma, Fang Wu, Ting Wan, Yiwen Sang, Qiuli Fu, Zhenwei Qin, Danni Lyu, Wei Wu, Jinfu Yin and Yabo Yang
    Citation: BMC Ophthalmology 2021 21:329
  7. The purpose of this study was to investigate diagnostic ability of peripapillary vessel density of primary angle closure glaucoma (PACG) eyes in quadrant and clock-hour sectors by optical coherence tomography ...

    Authors: Yongdong Lin, Shirong Chen and Mingzhi Zhang
    Citation: BMC Ophthalmology 2021 21:328
  8. Neurotrophic keratopathy (NK) is a relatively uncommon, underdiagnosed degenerative corneal disease that is caused by damage to the ophthalmic branch of the trigeminal nerve by conditions such as herpes simple...

    Authors: Reza Dana, Marjan Farid, Preeya K. Gupta, Pedram Hamrah, Paul Karpecki, Cathleen M. McCabe, Lisa Nijm, Jay S. Pepose, Stephen Pflugfelder, Christopher J. Rapuano, Arvind Saini, Sarah N. Gibbs and Michael S. Broder
    Citation: BMC Ophthalmology 2021 21:327
  9. Highly myopic eyes differ in morphology from emmetropic eyes, and the correct estimation of the vitreous volume is difficult. To explore an effective method to estimate ocular volume using refractive factors i...

    Authors: Xiaodan Jiang, Hongwei Deng, Chun Lung, Fanyin Wang, Shuang Li, Yanni Jiang and Mingyue Wang
    Citation: BMC Ophthalmology 2021 21:326
  10. Designing educational interventions tailored to the needs of Contact Lens Wearers (CLWs) are important and necessary. The present study aimed to determine the information needs of CLWs to educate and provide i...

    Authors: Fatemeh Falahati-Marvast, Fateme Alipour, Jamileh Farokhzadian and Leila Ahmadian
    Citation: BMC Ophthalmology 2021 21:325
  11. The combined corticosteroid regimen of the original Optic Neuritis Treatment Trial (ONTT) is used in many centers to treat optic neuritis. Though pattern reversal visual evoked potentials (PRVEPs) are a sensit...

    Authors: Padmini Dahanayake, Tharaka L. Dassanayake, Manoji Pathirage, Saman Senanayake, Mike Sedgwick and Vajira S. Weerasinghe
    Citation: BMC Ophthalmology 2021 21:324
  12. Ocular parasitosis can cause eye damage, which contribute to eye symptoms such as burning, itching and even blindness. It is uncommon to see the parasitosis lying in the sclera layer, neither it causing pteryg...

    Authors: Wenjie Zeng, Zhaoyi Pan, Jun Wang, Xianghui Deng and Wenmin Jiang
    Citation: BMC Ophthalmology 2021 21:323
  13. Full-thickness macular hole (FTMH) is a rare complication in retinitis pigmentosa (RP) patients and may increase intraoperative challenges. Furthermore, lens capsular flap transplantation and inverted internal...

    Authors: Chia-Ying Lee, Chung-May Yang, Chang-Hao Yang, Fung-Rong Hu and Ta-Ching Chen
    Citation: BMC Ophthalmology 2021 21:322
  14. Regular membrane peeling vitrectomy for epiretinal membrane (ERM) patients seldom causes large pigment epithelial detachment (PED). We presented an unusual case of the activation of quiescent polypoidal choroi...

    Authors: Yuelin Wang, Zhe Chen, Weihong Yu and Youxin Chen
    Citation: BMC Ophthalmology 2021 21:321
  15. We report a case of bilateral pachychoroid disease manifesting polypoidal choroidal vasculopathy (PCV) with punctate hyperfluorescent spot (PHS) in one eye, and peripheral exudative hemorrhagic choroidal retin...

    Authors: Yorihisa Kitagawa, Hiroyuki Shimada, Akiyuki Kawamura, Koji Tanaka, Ryusaburo Mori, Hajime Onoe and Hiroyuki Nakashizuka
    Citation: BMC Ophthalmology 2021 21:320
  16. Long-term use of topical, especially benzalkonium chloride (BAC)-preserved, antiglaucoma medications can cause a negative impact on the ocular surface. The aim of the study was to assess the effect of topical ...

    Authors: Lech Sedlak, Marta Świerczyńska, Weronika Borymska, Maria Zych and Dorota Wyględowska-Promieńska
    Citation: BMC Ophthalmology 2021 21:319
  17. Tick-borne encephalitis (TBE) is an infectious disease of the central nervous system caused by the TBE virus (TBEV), which is usually transmitted by a tick-bite, with increasing incidence in northeastern Europ...

    Authors: Nafsika Voulgari, Claire-May Blanc, Vanessa Guido, Daniele C. Rossi, Yan Guex-Crosier and Florence Hoogewoud
    Citation: BMC Ophthalmology 2021 21:315
  18. Ectopic thyroid tissue in the iris, also known as a thyroid glandular epithelial choristoma of the iris, has only been described twice in the literature. In both cases it remained asymptomatic.

    Authors: Helena Wagner, Claudia Auw-Hädrich, Martin Werner and Thomas Reinhard
    Citation: BMC Ophthalmology 2021 21:314
  19. Blepharochalasis is a rare eyelid disorder but eventually leading to destructive eyelid deformation. Until now the clinical and epidemiological data are unavailable. This study aimed to report the manifestatio...

    Authors: Jinqiong Zhou, Jingwen Ding and Dongmei Li
    Citation: BMC Ophthalmology 2021 21:313
  20. To evaluate the incidence of sustained elevation of intraocular pressure (SE-IOP) associated with intravitreal injections of anti-vascular endothelial growth factors (anti-VEGF) bevacizumab and aflibercept in ...

    Authors: Mikael Kähkönen, Raimo Tuuminen and Vesa Aaltonen
    Citation: BMC Ophthalmology 2021 21:312
  21. Myopic anisometropic amblyopia in pediatrics is one of the most challenging clinical situations that can face an ophthalmologist. Conventional correction modalities for myopic anisometropia, using spectacles, ...

    Authors: Fathy Fawzy Morkos, Nader F. Fawzy, Mohamed El Bahrawy, Nada Fathy and Rania Serag Elkitkat
    Citation: BMC Ophthalmology 2021 21:311
  22. This study aimed to develop a Thai version of the Dry Eye–Related Quality-of-Life Score (DEQS-Th) questionnaire and evaluate its validity, reliability, and feasibility among Thai participants.

    Authors: Sasiwimon Tansanguan, Napaporn Tananuvat, Nahathai Wongpakaran, Tinakon Wongpakaran and Somsanguan Ausayakhun
    Citation: BMC Ophthalmology 2021 21:310
  23. To analyze blood flow volume alteration that involved both retrobulbar artery and internal carotid artery (ICA) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) and to assess their rel...

    Authors: Zhiyong Fu, Hongyang Li and Yanling Wang
    Citation: BMC Ophthalmology 2021 21:309
  24. This article is a case report of pseudoxanthoma elasticum (PXE) which was diagnosed based on significant angioid streaks (AS) with choroidal neovascularization (CNV) and regain normal visual function by intrav...

    Authors: Chaoxiong Cui, Zhanyu Zhou, Yi Zhang and Ding Sun
    Citation: BMC Ophthalmology 2021 21:307
  25. Our aim was to determine associations of pachymetry, keratometry, and their changes with haze formation and corneal flattening after collagen cross-linking, and to analyse the relationship between postoperativ...

    Authors: Anita Csorba, Kinga Kránitz, Péter Dormán, Andrea Popper-Sachetti, Huba Kiss, Irén Szalai and Zoltán Zsolt Nagy
    Citation: BMC Ophthalmology 2021 21:306
  26. The nasal to temporal amplitudes ratio (N/T) of multifocal electroretinography (mfERG) scans measured within 5° of the macula can be used to detect glaucomatous change. The photopic negative response (PhNR) of...

    Authors: Hiroki Tanaka, Kyoko Ishida, Kenji Ozawa, Takuma Ishihara, Akira Sawada, Kiyofumi Mochizuki and Tetsuya Yamamoto
    Citation: BMC Ophthalmology 2021 21:305
  27. The efficacies of prism adaptation test (PAT) and monocular occlusion (MO) and their optimal test durations to detect the maximum angles of deviation at near and distance in eyes with intermittent exotropia (I...

    Authors: Ryota Takada, Fumiko Matsumoto, Akemi Wakayama, Takuya Numata, Fumi Tanabe, Kosuke Abe and Shunji Kusaka
    Citation: BMC Ophthalmology 2021 21:304
  28. The influences of intraocular pressure (IOP) elevations on the pulse waveform in the optic nerve head (ONH) were evaluated using laser speckle flowgraphy (LSFG) in normal subjects.

    Authors: Chie Iwase, Takeshi Iwase, Ryo Tomita, Tomohiko Akahori, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Citation: BMC Ophthalmology 2021 21:303
  29. Retinitis pigmentosa (RP) is a rare, progressive, and hereditary disorder that leads to the progressive loss of vision and visual field, and in some cases blindness. The specific relationship between RP and gl...

    Authors: Wei-ning Li, Xiu-juan Du, Yu-ting Zhang, Le-yi Wang and Jing Zhu
    Citation: BMC Ophthalmology 2021 21:302
  30. During the first wave of the COVID-19 pandemic, the need of treatment of urgent ophthalmological diseases and the possible risk of a SARS-CoV-2 infection had to be weighed against each other. In this questionn...

    Authors: Christoph Ehlken, Constantin von Medem, Maya Lüdemann, Anna Maria Kirsch and Johann Baptist Roider
    Citation: BMC Ophthalmology 2021 21:301
  31. To describe real-life data from wet age-related macular degeneration (AMD) patients treated with anti-vascular endothelial growth factors (VEGFs) and to compare our results with previous studies and clinical t...

    Authors: Paolo Corazza, Francesco Maria D’Alterio, Jamil Kabbani, Mostafa Mohamed Ragheb Alam, Stefano Mercuri, Harry Otway Orlans and Saad Younis
    Citation: BMC Ophthalmology 2021 21:300
  32. To evaluate the prevalence of myopia in school students in Urumqi, China, and explore the influence of the interaction between parental myopia and poor reading and writing habits on myopia to identify the at-r...

    Authors: Haonan Shi, Jing Fu, Xiaojing Liu, Yingxia Wang, Xianting Yong, Lan Jiang, Shaowei Ma, Zhe Yin, Jian Yao, Xuan Yao, Xueyi Chen and Tingting Wang
    Citation: BMC Ophthalmology 2021 21:299
  33. To compare the efficacies in astigmatic correction of simultaneous femtosecond laser-assisted cataract surgery (FLACS) with intrastromal arcuate keratotomy (ISAK) versus toric intraocular lens (IOL) implantati...

    Authors: Hye Ji Kwon, Hun Lee, Jin Ah. Lee, Jae Yong Kim and Hungwon Tchah
    Citation: BMC Ophthalmology 2021 21:298
  34. EPO (erythropoietin) and PDGF (platelet derived growth factor) families are thought to be associated with angiogenesis under hypoxic condition. The sharp rise of intraocular pressure in acute primary angle clo...

    Authors: Jing Wang, Ming-shui Fu, Min-wen Zhou, Bi-lian Ke, Zhi-hua Zhang and Xun Xu
    Citation: BMC Ophthalmology 2021 21:297
  35. There is a relative lack of information on the incidence and treatment of vision problems in Prader-Willi syndrome (PWS). Using data from the Global PWS Registry, we performed a cross-sectional study of vision...

    Authors: Jessica E. Bohonowych, Caroline J. Vrana-Diaz, Jennifer L. Miller, Shawn E. McCandless and Theresa V. Strong
    Citation: BMC Ophthalmology 2021 21:296
  36. To analyze the long-term effects of persistent subretinal fluid (SRF) on visual/anatomic outcomes according to the type of macular neovascularization (MNV) during relaxed treat-and-extend regimen with anti-vas...

    Authors: Kyung Tae Kim, Ju Byung Chae, Seungheon Lee, Eoi Jong Seo and Dong Yoon Kim
    Citation: BMC Ophthalmology 2021 21:294
  37. To compare the correction effect and optical quality after small-incision lenticule extraction (SMILE) and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia.

    Authors: Yewei Yin, Ying Lu, Aiqun Xiang, Yanyan Fu, Yang Zhao, Yuanjun Li, Tu Hu, Kaixuan Du, Shengfa Hu, Qiuman Fu, Xiaoying Wu and Dan Wen
    Citation: BMC Ophthalmology 2021 21:292
  38. This study aimed to present a simple method for evaluating transient eye closure (TEC) evoked by bright light and find the agreement between TEC and photosensitivity. We also assessed the associated factors wi...

    Authors: Won Jong Choi, Yeonji Jang, Seong-Joon Kim and Jae Ho Jung
    Citation: BMC Ophthalmology 2021 21:291
  39. Retinitis pigmentosa (RP) is a heterogeneous group of inherited ocular diseases that result in progressive retinal degeneration. This study aims to describe different Swept-source Optical Coherence Tomographic...

    Authors: Orjowan Shalabi, Zaher Nazzal, Muath Natsheh, Salam Iriqat, Michel Michaelides, Muyassar Ghanem, Alice Aslanian, Yahya Alswaiti and Alaa AlTalbishi
    Citation: BMC Ophthalmology 2021 21:289
  40. Topiramate (TPM) is a drug commonly used by neurophysicians and psychiatrists for a plethora of indications. Topiramate has been reported to induce acute angle closure glaucoma as an adverse effect. However, t...

    Authors: Mudit Tyagi, Shashwat Behera, Sirisha Senthil, Rajeev R. Pappuru, Vikas Ambiya and Siddharth Dikshit
    Citation: BMC Ophthalmology 2021 21:287
  41. To report the first Italian case of hypotrichosis with juvenile macular dystrophy complicated by macular neovascularization diagnosed through multimodal imaging.

    Authors: Giovanna Carnovale-Scalzo, Adriano Carnevali, Gabriele Piccoli, Domenico Ceravolo, Donatella Bruzzichessi, Rodolfo Iuliano, Rossana Tallerico, Valentina Gatti, Giuseppe Giannaccare and Vincenzo Scorcia
    Citation: BMC Ophthalmology 2021 21:284

    The Correction to this article has been published in BMC Ophthalmology 2024 24:26

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