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  1. The combined corticosteroid regimen of the original Optic Neuritis Treatment Trial (ONTT) is used in many centers to treat optic neuritis. Though pattern reversal visual evoked potentials (PRVEPs) are a sensit...

    Authors: Padmini Dahanayake, Tharaka L. Dassanayake, Manoji Pathirage, Saman Senanayake, Mike Sedgwick and Vajira S. Weerasinghe
    Citation: BMC Ophthalmology 2021 21:324
    Content type: Research Published on:

  2. Regular membrane peeling vitrectomy for epiretinal membrane (ERM) patients seldom causes large pigment epithelial detachment (PED). We presented an unusual case of the activation of quiescent polypoidal choroi...

    Authors: Yuelin Wang, Zhe Chen, Weihong Yu and Youxin Chen
    Citation: BMC Ophthalmology 2021 21:321
    Content type: Case report Published on:

  3. We report a case of bilateral pachychoroid disease manifesting polypoidal choroidal vasculopathy (PCV) with punctate hyperfluorescent spot (PHS) in one eye, and peripheral exudative hemorrhagic choroidal retin...

    Authors: Yorihisa Kitagawa, Hiroyuki Shimada, Akiyuki Kawamura, Koji Tanaka, Ryusaburo Mori, Hajime Onoe and Hiroyuki Nakashizuka
    Citation: BMC Ophthalmology 2021 21:320
    Content type: Case report Published on:

  4. Long-term use of topical, especially benzalkonium chloride (BAC)-preserved, antiglaucoma medications can cause a negative impact on the ocular surface. The aim of the study was to assess the effect of topical ...

    Authors: Lech Sedlak, Marta Świerczyńska, Weronika Borymska, Maria Zych and Dorota Wyględowska-Promieńska
    Citation: BMC Ophthalmology 2021 21:319
    Content type: Research Published on:

  8. Tick-borne encephalitis (TBE) is an infectious disease of the central nervous system caused by the TBE virus (TBEV), which is usually transmitted by a tick-bite, with increasing incidence in northeastern Europ...

    Authors: Nafsika Voulgari, Claire-May Blanc, Vanessa Guido, Daniele C. Rossi, Yan Guex-Crosier and Florence Hoogewoud
    Citation: BMC Ophthalmology 2021 21:315
    Content type: Case report Published on:

  9. Ectopic thyroid tissue in the iris, also known as a thyroid glandular epithelial choristoma of the iris, has only been described twice in the literature. In both cases it remained asymptomatic.

    Authors: Helena Wagner, Claudia Auw-Hädrich, Martin Werner and Thomas Reinhard
    Citation: BMC Ophthalmology 2021 21:314
    Content type: Case report Published on:

  10. Blepharochalasis is a rare eyelid disorder but eventually leading to destructive eyelid deformation. Until now the clinical and epidemiological data are unavailable. This study aimed to report the manifestatio...

    Authors: Jinqiong Zhou, Jingwen Ding and Dongmei Li
    Citation: BMC Ophthalmology 2021 21:313
    Content type: Research article Published on:

  11. To evaluate the incidence of sustained elevation of intraocular pressure (SE-IOP) associated with intravitreal injections of anti-vascular endothelial growth factors (anti-VEGF) bevacizumab and aflibercept in ...

    Authors: Mikael Kähkönen, Raimo Tuuminen and Vesa Aaltonen
    Citation: BMC Ophthalmology 2021 21:312
    Content type: Research Published on:

  12. Myopic anisometropic amblyopia in pediatrics is one of the most challenging clinical situations that can face an ophthalmologist. Conventional correction modalities for myopic anisometropia, using spectacles, ...

    Authors: Fathy Fawzy Morkos, Nader F. Fawzy, Mohamed El Bahrawy, Nada Fathy and Rania Serag Elkitkat
    Citation: BMC Ophthalmology 2021 21:311
    Content type: Research Published on:

  13. This study aimed to develop a Thai version of the Dry Eye–Related Quality-of-Life Score (DEQS-Th) questionnaire and evaluate its validity, reliability, and feasibility among Thai participants.

    Authors: Sasiwimon Tansanguan, Napaporn Tananuvat, Nahathai Wongpakaran, Tinakon Wongpakaran and Somsanguan Ausayakhun
    Citation: BMC Ophthalmology 2021 21:310
    Content type: Research Published on:

  14. To analyze blood flow volume alteration that involved both retrobulbar artery and internal carotid artery (ICA) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) and to assess their rel...

    Authors: Zhiyong Fu, Hongyang Li and Yanling Wang
    Citation: BMC Ophthalmology 2021 21:309
    Content type: Research Published on:

  16. This article is a case report of pseudoxanthoma elasticum (PXE) which was diagnosed based on significant angioid streaks (AS) with choroidal neovascularization (CNV) and regain normal visual function by intrav...

    Authors: Chaoxiong Cui, Zhanyu Zhou, Yi Zhang and Ding Sun
    Citation: BMC Ophthalmology 2021 21:307
    Content type: Case report Published on:

  17. Our aim was to determine associations of pachymetry, keratometry, and their changes with haze formation and corneal flattening after collagen cross-linking, and to analyse the relationship between postoperativ...

    Authors: Anita Csorba, Kinga Kránitz, Péter Dormán, Andrea Popper-Sachetti, Huba Kiss, Irén Szalai and Zoltán Zsolt Nagy
    Citation: BMC Ophthalmology 2021 21:306
    Content type: Research article Published on:

  18. The nasal to temporal amplitudes ratio (N/T) of multifocal electroretinography (mfERG) scans measured within 5° of the macula can be used to detect glaucomatous change. The photopic negative response (PhNR) of...

    Authors: Hiroki Tanaka, Kyoko Ishida, Kenji Ozawa, Takuma Ishihara, Akira Sawada, Kiyofumi Mochizuki and Tetsuya Yamamoto
    Citation: BMC Ophthalmology 2021 21:305
    Content type: Research article Published on:

  19. The efficacies of prism adaptation test (PAT) and monocular occlusion (MO) and their optimal test durations to detect the maximum angles of deviation at near and distance in eyes with intermittent exotropia (I...

    Authors: Ryota Takada, Fumiko Matsumoto, Akemi Wakayama, Takuya Numata, Fumi Tanabe, Kosuke Abe and Shunji Kusaka
    Citation: BMC Ophthalmology 2021 21:304
    Content type: Research article Published on:

  20. The influences of intraocular pressure (IOP) elevations on the pulse waveform in the optic nerve head (ONH) were evaluated using laser speckle flowgraphy (LSFG) in normal subjects.

    Authors: Chie Iwase, Takeshi Iwase, Ryo Tomita, Tomohiko Akahori, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Citation: BMC Ophthalmology 2021 21:303
    Content type: Research Published on:

  21. Retinitis pigmentosa (RP) is a rare, progressive, and hereditary disorder that leads to the progressive loss of vision and visual field, and in some cases blindness. The specific relationship between RP and gl...

    Authors: Wei-ning Li, Xiu-juan Du, Yu-ting Zhang, Le-yi Wang and Jing Zhu
    Citation: BMC Ophthalmology 2021 21:302
    Content type: Research Published on:

  22. During the first wave of the COVID-19 pandemic, the need of treatment of urgent ophthalmological diseases and the possible risk of a SARS-CoV-2 infection had to be weighed against each other. In this questionn...

    Authors: Christoph Ehlken, Constantin von Medem, Maya Lüdemann, Anna Maria Kirsch and Johann Baptist Roider
    Citation: BMC Ophthalmology 2021 21:301
    Content type: Research article Published on:

  23. To describe real-life data from wet age-related macular degeneration (AMD) patients treated with anti-vascular endothelial growth factors (VEGFs) and to compare our results with previous studies and clinical t...

    Authors: Paolo Corazza, Francesco Maria D’Alterio, Jamil Kabbani, Mostafa Mohamed Ragheb Alam, Stefano Mercuri, Harry Otway Orlans and Saad Younis
    Citation: BMC Ophthalmology 2021 21:300
    Content type: Research Published on:

  24. To evaluate the prevalence of myopia in school students in Urumqi, China, and explore the influence of the interaction between parental myopia and poor reading and writing habits on myopia to identify the at-r...

    Authors: Haonan Shi, Jing Fu, Xiaojing Liu, Yingxia Wang, Xianting Yong, Lan Jiang, Shaowei Ma, Zhe Yin, Jian Yao, Xuan Yao, Xueyi Chen and Tingting Wang
    Citation: BMC Ophthalmology 2021 21:299
    Content type: Research article Published on:

  25. To compare the efficacies in astigmatic correction of simultaneous femtosecond laser-assisted cataract surgery (FLACS) with intrastromal arcuate keratotomy (ISAK) versus toric intraocular lens (IOL) implantati...

    Authors: Hye Ji Kwon, Hun Lee, Jin Ah. Lee, Jae Yong Kim and Hungwon Tchah
    Citation: BMC Ophthalmology 2021 21:298
    Content type: Research article Published on:

  26. EPO (erythropoietin) and PDGF (platelet derived growth factor) families are thought to be associated with angiogenesis under hypoxic condition. The sharp rise of intraocular pressure in acute primary angle clo...

    Authors: Jing Wang, Ming-shui Fu, Min-wen Zhou, Bi-lian Ke, Zhi-hua Zhang and Xun Xu
    Citation: BMC Ophthalmology 2021 21:297
    Content type: Research article Published on:

  27. There is a relative lack of information on the incidence and treatment of vision problems in Prader-Willi syndrome (PWS). Using data from the Global PWS Registry, we performed a cross-sectional study of vision...

    Authors: Jessica E. Bohonowych, Caroline J. Vrana-Diaz, Jennifer L. Miller, Shawn E. McCandless and Theresa V. Strong
    Citation: BMC Ophthalmology 2021 21:296
    Content type: Research Published on:

  29. To analyze the long-term effects of persistent subretinal fluid (SRF) on visual/anatomic outcomes according to the type of macular neovascularization (MNV) during relaxed treat-and-extend regimen with anti-vas...

    Authors: Kyung Tae Kim, Ju Byung Chae, Seungheon Lee, Eoi Jong Seo and Dong Yoon Kim
    Citation: BMC Ophthalmology 2021 21:294
    Content type: Research Published on:

  31. To compare the correction effect and optical quality after small-incision lenticule extraction (SMILE) and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia.

    Authors: Yewei Yin, Ying Lu, Aiqun Xiang, Yanyan Fu, Yang Zhao, Yuanjun Li, Tu Hu, Kaixuan Du, Shengfa Hu, Qiuman Fu, Xiaoying Wu and Dan Wen
    Citation: BMC Ophthalmology 2021 21:292
    Content type: Research Published on:

  32. This study aimed to present a simple method for evaluating transient eye closure (TEC) evoked by bright light and find the agreement between TEC and photosensitivity. We also assessed the associated factors wi...

    Authors: Won Jong Choi, Yeonji Jang, Seong-Joon Kim and Jae Ho Jung
    Citation: BMC Ophthalmology 2021 21:291
    Content type: Research article Published on:

  34. Retinitis pigmentosa (RP) is a heterogeneous group of inherited ocular diseases that result in progressive retinal degeneration. This study aims to describe different Swept-source Optical Coherence Tomographic...

    Authors: Orjowan Shalabi, Zaher Nazzal, Muath Natsheh, Salam Iriqat, Michel Michaelides, Muyassar Ghanem, Alice Aslanian, Yahya Alswaiti and Alaa AlTalbishi
    Citation: BMC Ophthalmology 2021 21:289
    Content type: Research Published on:

  36. Topiramate (TPM) is a drug commonly used by neurophysicians and psychiatrists for a plethora of indications. Topiramate has been reported to induce acute angle closure glaucoma as an adverse effect. However, t...

    Authors: Mudit Tyagi, Shashwat Behera, Sirisha Senthil, Rajeev R. Pappuru, Vikas Ambiya and Siddharth Dikshit
    Citation: BMC Ophthalmology 2021 21:287
    Content type: Case report Published on:

  38. Corneal dystrophies are a group of rare, inherited disorders that are usually bilateral, symmetric, slowly progressive, and not related to environmental or systemic factors. The majority of publications presen...

    Authors: Anna Nowińska, Edyta Chlasta-Twardzik, Michał Dembski, Ewa Wróblewska-Czajka, Klaudia Ulfik-Dembska and Edward Wylęgała
    Citation: BMC Ophthalmology 2021 21:285
    Content type: Case report Published on:

  39. To report the first Italian case of hypotrichosis with juvenile macular dystrophy complicated by macular neovascularization diagnosed through multimodal imaging.

    Authors: Giovanna Carnovale-Scalzo, Adriano Carnevali, Gabriele Piccoli, Domenico Ceravolo, Donatella Bruzzichessi, Rodolfo Iuliano, Rossana Tallerico, Valentina Gatti, Giuseppe Giannaccare and Vincenzo Scorcia
    Citation: BMC Ophthalmology 2021 21:284
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Ophthalmology 2024 24:26

  40. Myopia has become a global public health problem. Children with early onset of myopia are at particular risk of complications associated with myopia. Younger children and children with greater initial myopic r...

    Authors: Lei Liu, Rui Li, Dan Huang, Xiao Lin, Hui Zhu, Yue Wang, Xiaoyan Zhao, Xiaohan Zhang and Hu Liu
    Citation: BMC Ophthalmology 2021 21:283
    Content type: Research article Published on:

  42. Dysfunction of lacrimal gland (LG) gains increasing attention in patients with thyroid-associated ophthalmopathy (TAO), while the underlying pathological change is still not fully established. This study aimed...

    Authors: Lu Chen, Hao Hu, Wen Chen, Qian Wu, Jiang Zhou, Huan-Huan Chen, Xiao-Quan Xu, Hai-Bin Shi and Fei-Yun Wu
    Citation: BMC Ophthalmology 2021 21:281
    Content type: Research Published on:

  43. To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM).

    Authors: Juan Gros-Otero, Samira Ketabi, Rafael Cañones-Zafra, Montserrat Garcia-Gonzalez, Cesar Villa-Collar, Santiago Casado and Miguel A. Teus
    Citation: BMC Ophthalmology 2021 21:280
    Content type: Research Published on:

  45. Globally, ocular morbidity has emerged as a major public concern with at least 2.2 billion people having vision impairment or blindness. Prisoners (inmates) tend to have limited access to health care especiall...

    Authors: Charity Zalwango, Pauline Ayebare, Pius Mwanja, Erima Denis, Moses Kasadhakawo, Micheal Mugerwa and Anne Ampaire
    Citation: BMC Ophthalmology 2021 21:278
    Content type: Research article Published on:

  46. Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. ...

    Authors: Mohamed Belmouhand, Christina Eckmann-Hansen, Tomas Ilginis, Eva Birgitte Leinøe, Bo Kok Mortensen and Michael Larsen
    Citation: BMC Ophthalmology 2021 21:277
    Content type: Case report Published on:

  47. Non-arteritic ischaemic optic neuropathy (NAION) is a rare but harmful complication of prone positioning. Prone mechanical ventilation is a therapeutic strategy which has been used extensively during the COVID...

    Authors: Kirsty Michelle Clarke, Vivi Riga, Amy-lee Shirodkar and Joel Meyer
    Citation: BMC Ophthalmology 2021 21:276
    Content type: Case report Published on:

  48. Superficial eye disorders are one of the most common complications of improper eye care in intensive care units that can lead to corneal ulcers and permanent eye damage. The aim of this study was to determine ...

    Authors: Azam Pourghaffari Lahiji, Mohsen Gohari, Samaneh Mirzaei and Khadijeh Nasiriani
    Citation: BMC Ophthalmology 2021 21:275
    Content type: Research Published on:

  50. PreserFlo® MicroShunt (PM) (also known as InnFocus® MicroShunt) is a subconjunctival stent implanted ab externo via a minimally invasive surgical procedure. The current indication is progressive, mild to moderate...

    Authors: Roxane Bunod, Mathieu Robin, Juliette Buffault, Chafik Keilani, Antoine Labbé and Christophe Baudouin
    Citation: BMC Ophthalmology 2021 21:273
    Content type: Case report Published on:
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