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  1. This study aims to evaluate choroidal thickness (CT), retinal thickness, ganglion cell-inner plexiform layer (GCIPL), and retinal nerve fiber layer (RNFL) structures in psoriasis patients using optical coheren...

    Authors: Asena Keles Sahin, Fatma Etgü and Aslihan Uzun
    Citation: BMC Ophthalmology 2021 21:233
  2. Intraocular lens (IOL) calculation using traditional formulas for post-corneal refractive surgery eyes can yield inaccurate results. This study aimed to compare the clinical accuracy of the newly developed Zha...

    Authors: Jun Zhang, Jie Shao, Li Zheng, Ye Shen and Xia Zhao
    Citation: BMC Ophthalmology 2021 21:231
  3. Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we e...

    Authors: William Greig Mitchell, Edward Christopher Dee and Leo Anthony Celi
    Citation: BMC Ophthalmology 2021 21:228
  4. Glaucoma is a leading cause of global blindness, especially preventable blindness. The increased prevalence of glaucoma has led to a growing demand for newer, safer, more rapid, and simpler treatments for the ...

    Authors: Noa Kapelushnik, Ari Leshno, Reut Singer, Ruth Huna-Baron, Yaniv Barkana and Alon Skaat
    Citation: BMC Ophthalmology 2021 21:226
  5. Filamentous fungi are ubiquitous in plants, water, and soil. The predominant fungi that infect the human cornea include Fusarium and Aspergillus species. The onset of fungal endophthalmitis is indolent, and typic...

    Authors: Yusuke Mitsuoka, Takeshi Soma, Kazuichi Maruyama and Kohji Nishida
    Citation: BMC Ophthalmology 2021 21:224
  6. Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical co...

    Authors: Santiago Delgado-Tirado, Alberto López-Miguel, Yazmin Báez-Peralta, Lucía González-Buendía, Itziar Fernández, Jorge L. Alió, Miguel J. Maldonado and Rosa M. Coco-Martín
    Citation: BMC Ophthalmology 2021 21:223
  7. To investigate the changes in retinal nerve fiber layer thickness and macular blood flow density during the preclinical stage of diabetic retinopathy and their relationship with blood glucose.

    Authors: Hui Li, Xiaobing Yu, Bodi Zheng, Shan Ding, Zhongqing Mu and Lixin Guo
    Citation: BMC Ophthalmology 2021 21:220
  8. The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients’ quality of life. No published studies on the epidemiology of dry eyes hav...

    Authors: Sarah Alkabbani, Lakshmanan Jeyaseelan, Anupama P. Rao, Sandeep P. Thakur and Pramod T. Warhekar
    Citation: BMC Ophthalmology 2021 21:219
  9. Insulin positively correlates with the length of the eye axis and is increased in the vitreous and serum of patients with pathological myopia (PM). How insulin influences the physiological process of retinal p...

    Authors: Yunqin Li, Junliang Jiang, Jin Yang, Libo Xiao, Qiyun Hua and Yue Zou
    Citation: BMC Ophthalmology 2021 21:218
  10. The refractive surgeries induce corneal higher order aberrations (C-HOAs). In this study, change of C-HOAs after small-incision lenticule extraction (SMILE) compared to femtosecond assisted laser in situ kerat...

    Authors: Mohammad Miraftab, Hassan Hashemi, Mohammadreza Aghamirsalim, Shiva Fayyaz and Soheila Asgari
    Citation: BMC Ophthalmology 2021 21:216
  11. The COVID-19 Pandemic has a great impact on hospitals and patients. The 14-day quarantine caused surgery of rhegmatogenous retinal detachment (RRD) postponed. We aimed to explore the risk factors of RRD progre...

    Authors: Meng Zhao, Jipeng Li, Haicheng She and Ningpu Liu
    Citation: BMC Ophthalmology 2021 21:215
  12. Mucopolysaccharidosis type VI (MPS VI) is a rare autosomal recessive inherited disease caused by mutations in the arylsulfatase B (ARSB) gene. MPS VI is a multisystemic disease resulting from a deficiency in aryl...

    Authors: Ming-Fang He, Ji Yang, Meng-Jie Dong, Yin-Ting Wang and Hai Liu
    Citation: BMC Ophthalmology 2021 21:214
  13. Trachomatous scarring (TS) results from repeated infection with the bacterium Chlamydia trachomatis. Pronounced scarring is an underlying cause of trachomatous trichiasis (TT) that can lead to blindness. Since th...

    Authors: Tigist Astale, Caleb D. Ebert, Andrew W. Nute, Mulat Zerihun, Demelash Gessese, Berhanu Melak, Eshetu Sata, Zebene Ayele, Gedefaw Ayenew, E. Kelly Callahan, Mahteme Haile, Taye Zeru, Zerihun Tadesse and Scott D. Nash
    Citation: BMC Ophthalmology 2021 21:213
  14. Ectopia lentis is the common ocular manifestation of homocystinuria resulting from cystathionine beta-synthase (CBS) deficiency which has a high risk of thromboembolic complications.

    Authors: Ning Hua, Yuxian Ning, Hui Zheng, Ledong Zhao, Xuehan Qian, Charles Wormington and Jingyun Wang
    Citation: BMC Ophthalmology 2021 21:212
  15. The aim of this study was to evaluate the in vivo confocal microscopic morphology of corneal subbasal nerves and its relationship with clinical parameters in patients with primary Sjögren’s syndrome in China.

    Authors: Fangting Li, Qin Zhang, Xin Ying, Jing He, Yuebo Jin, Huiwen Xu, Yaobin Cheng and Mingwei Zhao
    Citation: BMC Ophthalmology 2021 21:211
  16. One of the major side effects of Hydroxychloroquine (HCQ) is retinopathy. The aim of this study was to evaluate the Optical coherence tomography angiography (OCTA) parameters in a group of patients who have Hy...

    Authors: Mohammadreza Akhlaghi, Farzan Kianersi, Hamed Radmehr, Alireza Dehghani, Afsaneh Naderi Beni and Pegah Noorshargh
    Citation: BMC Ophthalmology 2021 21:209
  17. A reliable and effective method is required to deliver agent that can aid the in vivo imaging of retinal vessels. The aim of the present study was to evaluate retro-orbital (RO) injection of fluorescein-labele...

    Authors: Jizhu Li, Yuqing Wu, Bingqian Liu, Ying Huang, Qingxiu Wu, Haichun Li, Sainan Xiao, Ying Lin and Tao Li
    Citation: BMC Ophthalmology 2021 21:208
  18. This study described the clinical features of patients with pterygium and analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting combined with intraoperative mitomycin C, an...

    Authors: Waleed Alsarhani, Saeed Alshahrani, Mahmood Showail, Nawaf Alhabdan, Osama Alsumari, Abdullah Almalki, Abdulaziz Alsarhani, Adel Alluhaidan and Bader Alqahtani
    Citation: BMC Ophthalmology 2021 21:207
  19. COVID-19, a highly contagious respiratory virus, presents unique challenges to ophthalmology practice as a high-volume, office-based specialty. In response to the COVID-19 pandemic, many operational changes we...

    Authors: Karan Sethi, Emily S. Levine, Shiyoung Roh, Jeffrey L. Marx and David J. Ramsey
    Citation: BMC Ophthalmology 2021 21:206
  20. Berger’s IgA nephropathy (IgAN) is the most common primary glomerulonephritis. However, some rare cases of retinal manifestations have been described, with only two cases of retinal vasculopathy reported in th...

    Authors: Khaled El Matri, Francesca Amoroso, Olivia Zambrowski, Alexandra Miere and Eric H. Souied
    Citation: BMC Ophthalmology 2021 21:204
  21. The aim of this study is to analyze and compare the clinical results of toric intraocular lens (IOL) and monofocal IOL implantation when the target refraction value is -3 diopter (D) in cataract patients with ...

    Authors: Da Young Shin, Ho Sik Hwang, Hyun Seung Kim, Man Soo Kim and Eun Chul Kim
    Citation: BMC Ophthalmology 2021 21:203
  22. Numerous cases with ocular toxicity secondary to tamoxifen have been reported, and became more apparent with keratopathy, cataract, optic neuritis, macular holes, crystalline retinopathy with or without cystoi...

    Authors: Chuanyu Li, Jun Xiao, He Zou, Bo Yang and Lifu Luo
    Citation: BMC Ophthalmology 2021 21:201
  23. During panretinal photocoagulation (PRP), the outer retina, especially the photoreceptors, are destroyed. During such procedures, the impact of the retinal photocoagulation, which is performed in the same phot...

    Authors: Kentaro Nishida, Shizuka Takahashi, Hirokazu Sakaguchi, Shigeru Sato, Masanori Kanai, Akihiko Shiraki, Taku Wakabayashi, Chikako Hara, Yoko Fukushima, Susumu Sakimoto, Kaori Sayanagi, Ryo Kawasaki and Kohji Nishida
    Citation: BMC Ophthalmology 2021 21:200
  24. To describe the very early vault changes in the first month after Implantable Collamer Lens (ICL) implantation and to evaluate the effect of preoperative biometric factors on vault.

    Authors: Qiu-Jian Zhu, Wen-Jing Chen, Wei-Jian Zhu, Hai-Xiang Xiao, Man-Hui Zhu, Lie Ma, You Yuan and E. Song
    Citation: BMC Ophthalmology 2021 21:199
  25. To compare parsplana vitrectomy (PPV) with and without phacoemulsification to treat rhegmatogenous retinal detachment (RRD).

    Authors: Paolo Mora, Stefania Favilla, Giacomo Calzetti, Giulia Berselli, Lucia Benatti, Arturo Carta, Stefano Gandolfi and Salvatore A. Tedesco
    Citation: BMC Ophthalmology 2021 21:196
  26. Sympathetic ophthalmia (SO) is a bilateral diffuse uveitis that can arise after ocular trauma or ocular surgery in the inciting eye. Pars plana vitrectomy (PPV) is one of the risk factors for SO. Several repor...

    Authors: Yasuyuki Takai, Yoshihito Sakanishi, Masahiro Okamoto and Nobuyuki Ebihara
    Citation: BMC Ophthalmology 2021 21:195
  27. Cytomegalovirus (CMV) has been known to cause unilateral corneal endotheliitis with keratic precipitates and localized corneal edema, iridocyclitis, and secondary glaucoma. CMV endotheliitis is diagnosed based...

    Authors: Suguru Nakagawa, Hitoha Ishii, Mitsuko Takamoto, Toshikatsu Kaburaki, Kiyoshi Ishii and Takashi Miyai
    Citation: BMC Ophthalmology 2021 21:194
  28. The purpose of this study is to investigate the aqueous humor (AH) T lymphocyte subsets and cytokines of acute retinal necrosis (ARN) to elucidate the immunologic inflammatory features of this disorder.

    Authors: Hao Kang, Yunbo Wei, Ming Liu, Di Yu and Yong Tao
    Citation: BMC Ophthalmology 2021 21:193
  29. To investigate alterations in retinal microvasculature in eyes with preclinical diabetic retinopathy (DR) using ultra-wide field swept-source optical coherence tomography angiography (UWF SS OCTA).

    Authors: Jingyuan Yang, Bilei Zhang, Erqian Wang, Song Xia and Youxin Chen
    Citation: BMC Ophthalmology 2021 21:192
  30. Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy, affecting approximately 1 in 4000 individuals worldwide. The most common form of syndromic RP is Usher syndrome (USH) accounting for ap...

    Authors: Asif Naveed Ahmed, Raheel Tahir, Niamat Khan, Mushtaq Ahmad, Muhammad Dawood, Abdul Basit, Muhammad Yasin, Maha Nowshid, Muhammad Marwan, Komal Sultan and Shamim Saleha
    Citation: BMC Ophthalmology 2021 21:191
  31. The purpose of this study is to evaluate the influence of anti-vascular endothelial growth factor (VEGF) in the appearance or progression of epiretinal membranes (ERMs) in age-related macular degeneration (ARM...

    Authors: Hikari Taniguchi, Izumi Yoshida, Masashi Sakamoto and Takatoshi Maeno
    Citation: BMC Ophthalmology 2021 21:190
  32. Ocular damage, including damage to the conjunctiva, lacrimal gland, eyelids, and orbit, caused by Schistosoma haematobium is sporadic. We report a clinical case of orbital migration of schistosome eggs.

    Authors: Nouhoum Guirou, Serge Resnikoff, Abba Kaka Hadja Yakoura, Michel Gouda, Seydou Bakayoko, Abdoulaye Napo, Rodrigue Romulad Elien, Robert Della Rocca, Fatoumata Sylla and Lamine Traoré
    Citation: BMC Ophthalmology 2021 21:189
  33. We aimed to compare the outcomes of trabeculectomy combined with phacoemulsification and those of trabeculectomy followed by phacoemulsification.

    Authors: Shogo Arimura, Kentaro Iwasaki, Yusuke Orii, Yoshihiro Takamura and Masaru Inatani
    Citation: BMC Ophthalmology 2021 21:188

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