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  1. The World Health Organization (WHO) recommends annual mass azithromycin distribution until districts drop below 5% prevalence of trachomatous inflammation—follicular (TF). Districts with very low TF prevalence...

    Authors: Abdou Amza, Boubacar Kadri, Beido Nassirou, Ahmed M. Arzika, Ariana Austin, Fanice Nyatigo, Elodie Lebas, Benjamin F. Arnold, Thomas M. Lietman and Catherine E. Oldenburg
    Citation: BMC Ophthalmology 2021 21:15
    Content type: Study protocol Published on:

  3. A prospective cohort study was performed to evaluate whether the Optical Quality Analysis System (OQAS) can serve as a valuable additional indicator for appropriate posterior capsulotomy referral.

    Authors: Bo Lu, Weijie Zhu, Yu Fan, Dong Shi and Liwei Ma
    Citation: BMC Ophthalmology 2021 21:7
    Content type: Research article Published on:

  5. To study the enlargement rate of primary geographic atrophy (GA) before and after diagnosis of a secondary choroidal neovascularization (CNV) treated with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Jakob Siedlecki, Caroline Koch, Benedikt Schworm, Raffael Liegl, Thomas Kreutzer, Karsten U. Kortuem, Ricarda Schumann, Siegfried G. Priglinger and Armin Wolf
    Citation: BMC Ophthalmology 2021 21:4
    Content type: Research article Published on:

  6. To assess the prevalence and demographics of lower eyelid epiblepharon in Chinese preschool children and to evaluate its association with refractive errors.

    Authors: Deyi Zhuo, Si Chen, Xiaofang Ren, Bingsong Wang, Linbo Liu and Lin Xiao
    Citation: BMC Ophthalmology 2021 21:3
    Content type: Research article Published on:

  7. To compare different clinical and Spectral-Domain Optical Coherence Tomography (SD-OCT) features of high myopic eyes with Stickler syndrome (STL) with matched controls.

    Authors: Olivia Xerri, Federico Bernabei, Elise Philippakis, Cyril Burin-Des-Roziers, Pierre-Olivier Barale, Olivier Laplace, Claire Monin, Dominique Bremond-Gignac, Gilles Guerrier, Sophie Valleix, Antoine Brezin and Pierre-Raphaël Rothschild
    Citation: BMC Ophthalmology 2021 21:2
    Content type: Research article Published on:

  8. Vision loss is a major public health concern that significantly affects developing countries, including South Africa. Although existing literature have reported on the prevalence, causes, and impact of vision ...

    Authors: Emmanuel Kofi Addo, Kwadwo Owusu Akuffo, Ronel Sewpaul, Natisha Dukhi, Eldad Agyei-Manu, Akosua Kesewah Asare, David Ben Kumah, Moses Awuni and Priscilla Reddy
    Citation: BMC Ophthalmology 2021 21:1
    Content type: Research article Published on:

  9. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jaeryung Kim, Sung-Ho Choi, Dong Hui Lim, Gil-Joong Yoon and Tae-Young Chung
    Citation: BMC Ophthalmology 2020 20:492
    Content type: Correction Published on:

    The original article was published in BMC Ophthalmology 2020 20:192

  10. The purpose of the study was to explore the immunological components that are responsible for the proliferative alterations in the different forms of retinal detachment (RD).

    Authors: Anikó Balogh, Tibor Milibák, Viktória Szabó, Zoltán Zsolt Nagy, Kai Kaarniranta and Miklós D. Resch
    Citation: BMC Ophthalmology 2020 20:491
    Content type: Research article Published on:

  11. The aim of this retrospective study was to compare the efficacy and safety profile of a single XEN-microstent in different types of primary and secondary open angle glaucoma.

    Authors: Marc Schargus, Theresa Theilig, Matus Rehak, Catharina Busch, Caroline Bormann and Jan Darius Unterlauft
    Citation: BMC Ophthalmology 2020 20:490
    Content type: Research article Published on:

  12. Anterior uveitis secondary to topical brimonidine administration is rare and not well-defined. In glaucoma patients using brimonidine, one must consider this phenomenon to avoid mis-diagnosis and over-treatmen...

    Authors: Susanne Hopf, Karl Mercieca, Norbert Pfeiffer and Verena Prokosch-Willing
    Citation: BMC Ophthalmology 2020 20:489
    Content type: Research article Published on:

  13. Collagen cross-linking of the sclera is a promising approach to strengthen scleral rigidity and thus to inhibit eye growth in progressive myopia. Additionally, cross-linking might inhibit degrading processes i...

    Authors: Konstantin Krasselt, Cornelius Frommelt, Robert Brunner, Franziska Georgia Rauscher, Mike Francke and Nicole Körber
    Citation: BMC Ophthalmology 2020 20:488
    Content type: Research article Published on:

  14. Choroidal ganglioneuroma is an extremely rare tumor, and there is little knowledge regarding its pathogenesis. We aimed to investigate the phenotypic and genetic alterations in one sporadic patient with a rare...

    Authors: Zhaoxin Jiang, Ting Zhang, Chonglin Chen, Limei Sun, Songshan Li and Xiaoyan Ding
    Citation: BMC Ophthalmology 2020 20:487
    Content type: Research article Published on:

  15. Chorioretinal fold (CFs) is a rare condition resulting from undulations in the choriocapillaris, Bruch's membrane, retinal pigment epithelium and occasionally neurosensory retina. It can be idiopathic or due t...

    Authors: Nan-Ni Chen, Chien-Hsiung Lai, Tsai Yueh-Ju and Chau -Yin Chen
    Citation: BMC Ophthalmology 2020 20:486
    Content type: Case report Published on:

  16. Usher syndrome is a disease with a heterogeneous phenotype and genotype. Our purpose was to identify the gene mutation in a Chinese family with Usher syndrome type 2 and describe the clinical features.

    Authors: Dongjun Xing, Huaiyu Zhou, Rongguo Yu, Linni Wang, Liying Hu, Zhiqing Li and Xiaorong Li
    Citation: BMC Ophthalmology 2020 20:485
    Content type: Case report Published on:

  17. We have generated two mouse models, in one by inserting the human lens αAN101D transgene in CRYαAN101D mice, and in the other by inserting human wild-type αA-transgene in CRYαAWT mice. The CRYαAN101D mice develop...

    Authors: Om Srivastava, Kiran Srivastava, Roy Joseph and Landon Wilson
    Citation: BMC Ophthalmology 2020 20:484
    Content type: Research article Published on:

  18. Choroidal neovascularization (CNV) in pregnancy has rarely been described. A differential diagnosis between inflammatory, idiopathic, and myopic CNV may be challenging. Moreover, there is no consensus on manag...

    Authors: Emilia Maggio, Maurizio Mete, Antonio Polito, Gloria Parrozzani and Grazia Pertile
    Citation: BMC Ophthalmology 2020 20:483
    Content type: Case report Published on:

  19. Ocular involvement in catastrophic antiphospholipid syndrome (CAPS), a rare, life-threatening form of antiphospholipid syndrome (APS) that results in multiorgan failure and a high mortality rate, has rarely be...

    Authors: Young In Yun, Ji Hyun Kim, Seon Hee Lim, Yo Han Ahn, Hee Gyung Kang, Il-Soo Ha and Baek-Lok Oh
    Citation: BMC Ophthalmology 2020 20:482
    Content type: Case report Published on:

  20. The purpose of this study was to investigate the agreement of lens thickness (LT) measurements made by contact A-scan ultrasonography and Lenstar LS900 as well as the influence of anterior chamber depth (ACD) ...

    Authors: Jiayi Xu, Chen Li, Lijun Wang, Caixin Li, Xin Li and Peirong Lu
    Citation: BMC Ophthalmology 2020 20:481
    Content type: Research article Published on:

  21. Generally, the loss rate of human endothelial cells (HCEC) in routine cataract surgery is 8.5%. When the corneal endothelial cells density (ECD) drops, the HCEC may decompensate to keep cornea dehydration whic...

    Authors: Fang-Chi Hsiao, Hung-Ta Chen, Kuan-Jen Chen, Yi-Jen Hsueh, Yaa-Jyuhn James Meir, Tsai-Te Lu, Chao-Min Cheng, Wei-Chi Wu and Hung-Chi Chen
    Citation: BMC Ophthalmology 2020 20:480
    Content type: Case report Published on:

  22. We report a case of white circular spots of iridian atrophy, which we will call “polka dots” pattern, as a rare ophthalmological finding associated with uveitis secondary to varicella-zoster virus and Toxoplasma ...

    Authors: Juliana Muñoz-Ortiz, Olga Lorena Rubio-Romero, Maria Cecilia Cedeño, Karla Arteaga-Rivera and Alejandra de-la-Torre
    Citation: BMC Ophthalmology 2020 20:479
    Content type: Case report Published on:

  23. The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically ev...

    Authors: Congling Zhao, Chunyan Cai, Qiang Ding and Hongbin Dai
    Citation: BMC Ophthalmology 2020 20:478
    Content type: Research article Published on:

  24. To evaluate the choroidal changes in Sturge-Weber syndrome (SWS) secondary glaucoma and non-glaucoma port-wine stain (PWS) patients by enhanced depth imaging optical coherence tomography (EDI-OCT).

    Authors: Yue Wu, Lulu Huang, Yixin Liu, Li Xu and Wenyi Guo
    Citation: BMC Ophthalmology 2020 20:477
    Content type: Research article Published on:

  25. To report undescribed characteristics of patients with bilateral diffuse uveal melanocytic proliferation (BDUMP) on ultrasound biomicroscopy (UBM) and high-frequency B-scan ultrasonography.

    Authors: Jingli Guo, Wenyi Tang, Wei Liu, Min Zhou, Qing Chang, Chunhui Jiang, Gezhi Xu, Wenji Wang and Qian Chen
    Citation: BMC Ophthalmology 2020 20:476
    Content type: Case report Published on:

  28. Offspring of parent(s) with age-related macular degeneration (AMD) have a 45% lifetime risk of developing the disease. High foveal macular pigment optical density (MPOD) is protective, whereas individuals with...

    Authors: Grant A. Rutledge, Steven G. Pratt, Stuart P. Richer, Byki Huntjens, C. Blake Perry, Gunilla Pratt and Carla Podella
    Citation: BMC Ophthalmology 2020 20:473
    Content type: Research article Published on:

  29. Structural changes of the choroid, such as choroidal thickening, have been indicated in amblyopic eyes with hyperopic anisometropia as compared to fellow or healthy eyes. The purpose of the present study was t...

    Authors: Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Tsutomu Yamashita, Tsuyoshi Yoneda, Atsushi Fujiwara, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Goro Maehara and Kiyoshi Yaoeda
    Citation: BMC Ophthalmology 2020 20:472
    Content type: Research article Published on:

  30. To analyze the distribution of manifest lesions of diabetic retinopathy (DR) by fundus fluorescein angiography (FFA) and color fundus photography (FP).

    Authors: Xiaoli Li, Jie Xie, Liang Zhang, Ying Cui, Guanrong Zhang, Jun Wang, Aiping Zhang, Xiangting Chen, Tian Huang and Qianli Meng
    Citation: BMC Ophthalmology 2020 20:471
    Content type: Research article Published on:

  31. Proliferative retinopathy is an uncommon feature of Vogt Koyanagi Harada (VKH) disease which might indicate poor uveitis control in these patients. We aim to describe the clinical features and outcome of manag...

    Authors: Moustafa S. Magliyah, Abdulmajeed S. Al-Fakhri and Hassan A. Al-Dhibi
    Citation: BMC Ophthalmology 2020 20:470
    Content type: Case report Published on:

  32. To compare the efficiency of preloaded vs manually loaded IOL (P-IOL vs M-IOL, respectively) delivery systems in cataract surgery in the largest ambulatory surgery center of Northwestern China.

    Authors: Yazhen Wu, Hong Yan and Weijia Yan
    Citation: BMC Ophthalmology 2020 20:469
    Content type: Research article Published on:

  33. To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient.

    Authors: Pierre-Guillaume Deliège, Justine Bastien, Laetitia Mokri, Charlotte Guyot-Colosio, Carl Arndt and Philippe Rieu
    Citation: BMC Ophthalmology 2020 20:468
    Content type: Case report Published on:

  34. Diabetic retinopathy (DR) is a serious microvascular complication of type 2 diabetes mellitus (T2DM). The aim of this retrospective study was to reveal the risk factors for the severity of DR in individuals wi...

    Authors: Donghe Chen, Xiufang Sun, Xinxin Zhao and Ying Liu
    Citation: BMC Ophthalmology 2020 20:467
    Content type: Research article Published on:

  37. To examine the clinical features of acute acquired comitant esotropia (AACE) and to evaluate the clinical effectiveness of a single injection of botulinum toxin type A (BTXA) on binocular visual function (BVF).

    Authors: Luyao Tong, Xiaoning Yu, Xiajing Tang, Yidong Zhang, Sifan Zheng and Zhaohui Sun
    Citation: BMC Ophthalmology 2020 20:464
    Content type: Research article Published on:

  39. The current National Health Insurance scheme in Taiwan reimburses 3 initial plus 4 additional injections of ranibizumab 0.5 mg for eligible patients with neovascular age-related macular degeneration (nAMD). Th...

    Authors: Wen-Chuan Wu, Jiann-Torng Chen, Ching-Yao Tsai, Chien-Liang Wu, Cheng-Kuo Cheng, Yun-Dun Shen, Arslan Tsai and Pei-Chang Wu
    Citation: BMC Ophthalmology 2020 20:462
    Content type: Research article Published on:

  46. To compare the clinical characteristics of dry eye patients with ocular neuropathic pain features according to the types of sensitization based on the Ocular Pain Assessment Survey (OPAS).

    Authors: Jonghwa Kim, Hyeon Jeong Yoon, In Cheon You, Byung Yi Ko and Kyung Chul Yoon
    Citation: BMC Ophthalmology 2020 20:455
    Content type: Research article Published on:

  47. To prospectively evaluate surgical results following implantation of rotationally asymmetric, plate-haptic, refractive segmented multifocal toric intraocular lenses (IOLs) with near addition of + 1.5 diopters ...

    Authors: Tetsuro Oshika, Kazuno Negishi, Toru Noda, Hiroyuki Arai, Mikio Inamura, Yasushi Inoue, Teruyuki Miyoshi, Yoshifumi Fujita, Kazunori Miyata and Yumi Hasegawa
    Citation: BMC Ophthalmology 2020 20:454
    Content type: Research article Published on:

  48. Routine eye examination plays a vital role in detecting diabetic retinopathy in its earliest stage before the onset of blindness. Patients’ knowledge about the nature and the consequences of diabetic retinopat...

    Authors: Abel Sinshaw Assem, Mebratu Mulusew Tegegne, Destaye Shiferaw Alemu, Asamere Tsegaw Woredekal and Tsehay Kassa Tefera
    Citation: BMC Ophthalmology 2020 20:453
    Content type: Research article Published on:

  49. The aim of our study was to assess changes of tear film osmolarity after micro-incision 25G+ pars plana vitrectomy (PPV) in a prospective study.

    Authors: J. Němčanský, A. Kopecký and P. Mašek
    Citation: BMC Ophthalmology 2020 20:452
    Content type: Research article Published on:
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