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  1. Tear film stability is the key event in ocular surface diseases. The purpose of this study is to evaluate spatial and temporal progression of the tear film breakup using an automatic non-invasive device.

    Authors: Adriano Guarnieri, Elena Carnero, Anne-Marie Bleau, Nicolás López de Aguileta Castaño, Marcos Llorente Ortega and Javier Moreno-Montañés
    Citation: BMC Ophthalmology 2020 20:12
  2. To compare the anatomical and functional outcomes of the inverted internal limiting membrane (ILM) flap technique and the complete ILM removal in the treatment of large stage 4 macular hole (MH) > 400 μm and t...

    Authors: Prithvi Ramtohul, Eric Parrat, Danièle Denis and Umberto Lorenzi
    Citation: BMC Ophthalmology 2020 20:11
  3. Developing objective and repeatable indicators to evaluate the efficacy of PVRL treatment is important. The quantification of vitreous cells is a traditional criterion; however slight changes are difficult to ...

    Authors: Huiying Zhao, Xiaona Wang, Yu Mao and Xiaoyan Peng
    Citation: BMC Ophthalmology 2020 20:10
  4. Glaucoma is a global public health problem and it is the leading cause of irreversible blindness worldwide. Even though public knowledge of glaucoma is a key for early case identification and prevention of bli...

    Authors: Zewdu Yenegeta, Ayanaw Tsega, Yezinash Addis and Fisseha Admassu
    Citation: BMC Ophthalmology 2020 20:8
  5. To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.

    Authors: Wei Xu, Weijing Cheng, Xiaoyuan Cui and Guoxing Xu
    Citation: BMC Ophthalmology 2020 20:7
  6. The Valsalva maneuver (VM) is widely used in daily life, and has been reported to cause high intraocular pressure (IOP). This study aimed to assess changes in IOP, the Schlemm’s canal (SC), autonomic nervous s...

    Authors: Li Sun, Wei Chen, Zhiqi Chen, Yan Xiang, Jingmin Guo, Tian Hu, Qiongfang Xu, Hong Zhang and Junming Wang
    Citation: BMC Ophthalmology 2020 20:5
  7. To elucidate whether eyelid squinting improves near and distance vision in against-the-rule (ATR) and with-the-rule (WTR) simple myopic astigmatism in pseudophakic eyes.

    Authors: Jay Won Rhim, Youngsub Eom, Seo Yeon Park, Su-Yeon Kang, Jong Suk Song and Hyo Myung Kim
    Citation: BMC Ophthalmology 2020 20:4
  8. Prevention of myopia has become a public health priority in China. This study is to investigate the prevalence of myopia and vision impairment, and their associated factors in school students in eastern China.

    Authors: Jianyong Wang, Gui-shuang Ying, Xiaojin Fu, Ronghua Zhang, Jia Meng, Fang Gu and Juanjuan Li
    Citation: BMC Ophthalmology 2020 20:2
  9. To compare the visual and refractive outcomes of femtosecond laser assisted cataract surgery (FLACS) using Victus platform (Technolas Bausch and Lomb (B&L), Munich, Germany) and conventional phacoemulsificatio...

    Authors: Mohamed Shafik Shaheen, Amir AbouSamra, Hany Ahmed Helaly, Amr Said and Ahmed Elmassry
    Citation: BMC Ophthalmology 2020 20:1
  10. To compare the glaucoma diagnostic ability of the ganglion cell-inner plexiform layer (GCIPL) thickness depending on the range around the fovea using wide-angle, swept-source optical coherence tomography (SS-O...

    Authors: Jae Ho Jung, Je Hyun Seo, Min Seung Kang and Jonghoon Shin
    Citation: BMC Ophthalmology 2019 19:270
  11. Intraventricular silicone oil is a relatively rare complication resulted from silicone oil tamponade to treat retinal detachment. It is occasionally reported in previous literature. To the best of our knowledg...

    Authors: Juntao Cao, Lianlong Bian, Pengpeng Zhou and Jianchun Tu
    Citation: BMC Ophthalmology 2019 19:269
  12. Previous case reports have demonstrated the occurrence of ischemic optic neuropathy (ION) following intravitreal injections of antivascular endothelial growth factor (anti-VEGF). However, no previous studies h...

    Authors: Yu-Yen Chen, Pesus Chou, Yu-Fang Huang, Hung-Jen Chien, Yu-Chieh Wu, Chia-Chi Lee, Li-Ying Huang and Hsin-Hua Chen
    Citation: BMC Ophthalmology 2019 19:268
  13. The relationship between anti-estrogen drugs and macular telangiectasia type 2 (MacTel-2) remains unknown. Here we report a case with anti-estrogen maculopathy resembling MacTel-2 with improved visual function...

    Authors: Akihiro Shinkai, Wataru Saito, Yuki Hashimoto and Susumu Ishida
    Citation: BMC Ophthalmology 2019 19:267
  14. After pars plana vitrectomy with internal limiting membrane (ILM) peeling and gas tamponade, patients are often required to remain in a face-down position (FDP) to allow the gas bubble to push against the macu...

    Authors: Ting Ye, Ji-guo Yu, Lin Liao, Lan Liu, Ting Xia and Lei-lei Yang
    Citation: BMC Ophthalmology 2019 19:265
  15. To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique.

    Authors: Yuyan Liu, Changlong Wu, Ying Wang, Yi Dong, Dongqing Liang, Bo Xiao, Quanhong Han and Yanhua Chu
    Citation: BMC Ophthalmology 2019 19:264
  16. Epidemic keratoconjunctivitis (EKC) is one of the most common eye infections worldwide. The analysis of clinical manifestations in different age groups help better know the disease. This study aims to provide ...

    Authors: Wenbo Hou, Xuguang Sun, Jun Feng, Yang Zhang and Zhiqun Wang
    Citation: BMC Ophthalmology 2019 19:262
  17. Fluorescein angiography is an important and frequently used diagnostic tool in ophthalmological practice. In this case report we describe a patient who experienced an anaphylactic reaction after the injection ...

    Authors: Annemieke Clementine Bouman, Damaris de Kruijf, Judith Maria Antonia Emmen, Thijs Clemens David Rettig, Maria Jolande Charlotte Kooijman-de Groot and Miriam Christina Faes
    Citation: BMC Ophthalmology 2019 19:261
  18. Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1...

    Authors: Xiangyang Zhang, Xuemin Tian, Baike Zhang, Lisa Guo, Xiaodan Li and Yong Jia
    Citation: BMC Ophthalmology 2019 19:260
  19. In this retrospective study the relationship between intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness and pathologic hypersignal in optic nerve segments on 3D double inversion recovery (D...

    Authors: Thomas Sartoretti, Jörg Stürmer, Elisabeth Sartoretti, Arash Najafi, Árpád Schwenk, Michael Wyss, Christoph Binkert and Sabine Sartoretti-Schefer
    Citation: BMC Ophthalmology 2019 19:258
  20. Accurate measurement and reconstruction of orbital soft tissue is important to diagnosis and treatment of orbital diseases. This study applied an interactive graph cut method to orbital soft tissue precise seg...

    Authors: Qingyao Ning, Xiaoyao Yu, Qi Gao, Jiajun Xie, Chunlei Yao, Kun Zhou and Juan Ye
    Citation: BMC Ophthalmology 2019 19:256
  21. Floppy eyelid syndrome is a disorder in which the tarsal plate is easily distensible and is currently treated with conservative or surgical measures. Human tarsal plate contains type I collagen, which is cross...

    Authors: Sarah W. DeParis, Angela Y. Zhu, Shoumyo Majumdar, Jing Tian, Jennifer Elisseeff, Albert S. Jun and Nicholas R. Mahoney
    Citation: BMC Ophthalmology 2019 19:255
  22. XEN® gel stent (Allergan, Dublin/Republic of Ireland) is a relatively new microinvasive glaucoma device providing an ab-interno approach to the subconjunctival space for aqueous drainage and reduction of intra...

    Authors: Chandni Gupta and Divya Mathews
    Citation: BMC Ophthalmology 2019 19:253
  23. Uncorrected refractive errors contribute enormously to the burden of avoidable visual impairment worldwide. There is a huge disparity in different parts of the globe in context to spectacle coverage for distan...

    Authors: Sumit Malhotra, Mani Kalaivani, Ramashankar Rath, Manya Prasad, Praveen Vashist, Noopur Gupta, Suraj Singh Senjam and Sanjeev Kumar Gupta
    Citation: BMC Ophthalmology 2019 19:252
  24. To compare the changes in the anterior segment after femtosecond laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) using a dual rotating Scheimpflug (DRS) analyzer (Galile...

    Authors: Bu Ki Kim, Su Joung Mun, Young Hoon Yang, Ji Sun Kim, Jun Hyung Moon and Young Taek Chung
    Citation: BMC Ophthalmology 2019 19:251
  25. Retinal pigment epithelium cells (RPEs) are critical for maintaining retinal homeostasis. Accumulation of age-related lipofuscin, N-retinylidene-N-retinylethanolamine (A2E), makes RPEs vulnerable to blue light...

    Authors: Jingyang Feng, Yuhong Chen, Bing Lu, Xiangjun Sun, Hong Zhu and Xiaodong Sun
    Citation: BMC Ophthalmology 2019 19:249
  26. The study was proposed to determine whether nerve growth factor (NGF) combined with an internal limiting membrane (ILM) insertion was effective in the large idiopathic full-thickness macular hole (iFTMH) therapy.

    Authors: Luyi Zhang, Xiaoxia Li, Xiaoli Yang, Yu Shen and Miaoqin Wu
    Citation: BMC Ophthalmology 2019 19:247
  27. Alström syndrome (AS) is a rare monogenic disorder characterized by progressive multi-organ pathology including retinal degeneration, hearing impairment and type 2 diabetes. Here we present clinical features i...

    Authors: Maria F. Shurygina, Maria A. Parker, Catie L. Schlechter, Rui Chen, Yumei Li, Richard G. Weleber, Paul Yang and Mark E. Pennesi
    Citation: BMC Ophthalmology 2019 19:246
  28. We aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia.

    Authors: Shuyi Yuan, Shuxian Zhang, Yanglin Jiang and Lihua Li
    Citation: BMC Ophthalmology 2019 19:242
  29. RP (retinitis pigmentosa) is a group of hereditary retinal degenerative diseases. XLRP is a relatively severe subtype of RP. Thus, it is necessary to identify genes and mutations in patients who present with X...

    Authors: Zhimeng Zhang, Hehua Dai, Lei Wang, Tianchang Tao, Jing Xu, Xiaowei Sun, Liping Yang and Genlin Li
    Citation: BMC Ophthalmology 2019 19:240
  30. So far only single cases with short follow-up have been reported on the use of intravitreal anti-VEGF for traumatic choroidal neovascularizations (CNV). This paper reports a large case series of patients with ...

    Authors: T. Barth, F. Zeman, H. Helbig and M.-A. Gamulescu
    Citation: BMC Ophthalmology 2019 19:239
  31. Repeated surgery excisions could induce obvious irregular astigmatism in patients with recurrent pterygium. Our study is aimed to illustrate the effect of adjunct excimer laser phototherapeutic keratectomy (PT...

    Authors: Di Chen, Xiaowei Liu, Qin Long, Zhonghai Wang and Ying Li
    Citation: BMC Ophthalmology 2019 19:238
  32. Anterior high-resolution optical coherence tomography (HR-OCT) is a novel non-invasive in vivo imaging modality that can assist in the diagnosis and management of various ophthalmic pathologies. The implementa...

    Authors: Yi-Syun Shen, Joseph L. Hu and Chao-Chien Hu
    Citation: BMC Ophthalmology 2019 19:235
  33. Hypocalcemia is a derangement in serum calcium level due to a vast spectrum of disorders, but the most common cause is surgery, usually thyroid gland surgery. Symptoms of hypocalcemia can be due to increased n...

    Authors: Kumale Tolesa Daba, Dagmawit Kifle Weldemichael and Gersam Abera Mulugeta
    Citation: BMC Ophthalmology 2019 19:233

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