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  1. Microvascular and macrovascular complications in diabetes stem from chronic hyperglycemia and are thought to have overlapping pathophysiology. The aim of this study was to investigate the incidence rate of hos...

    Authors: Bao-Anh Nguyen-Khoa, Earl L Goehring Jr, Winifred Werther, Anne E Fung, Diana V Do, Rajendra S Apte and Judith K Jones

    Citation: BMC Ophthalmology 2012 12:11

    Content type: Research article

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  2. Vascular endothelial growth factor (VEGF) plays an important role in ocular physiology. Anti-VEGF agents are now used for treatment of common retinal diseases. This study characterises the vasoactive propertie...

    Authors: Er-Ning Su, Stephen J Cringle, Ian L McAllister and Dao-Yi Yu

    Citation: BMC Ophthalmology 2012 12:10

    Content type: Research article

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  3. Several studies have investigated the effect of latanoprost on intraocular pressure (IOP). We compared the IOP-lowering effects of three higher concentrations of latanoprost with the commercially available con...

    Authors: David Eveleth, Carla Starita and Charles Tressler

    Citation: BMC Ophthalmology 2012 12:9

    Content type: Research article

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  4. Retinal dystrophies display a considerably wide range of phenotypic variability, which can make diagnosis and clinical staging difficult. The aim of the study is to analyze the contribution of retro-mode imagi...

    Authors: Battaglia Parodi Maurizio, Iacono Pierluigi, Kontadakis Stelios, Vergallo Stefano, Cascavilla Marialucia, Zucchiatti Ilaria and Bandello Francesco

    Citation: BMC Ophthalmology 2012 12:8

    Content type: Research article

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  5. Methicillin-resistant Staphylococcus aureus is a serious cause of morbidity and mortality in hospital environment, but also, lately, in the community. This case report is, to our knowledge, the first detailed des...

    Authors: Evangelia E Tsironi, Fani Zacharaki, Ioanna N Grivea, Sophia V Tachmitzi, Aspasia N Michoula, Marianna Vlychou, Efthimia Petinaki and George A Syrogiannopoulos

    Citation: BMC Ophthalmology 2012 12:7

    Content type: Case report

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  6. Major-histocompatibility-complex class I-related chain A (MICA) antigens are the ligands of NKG2D, which is an activating or coactivating receptor expressed on human NK cells and CD8+T cells. We sought to determi...

    Authors: Jiaxu Hong, Ting Qiu, Tingting Qian, Gang Li, Xiaobo Yu, Junyi Chen, Qihua Le, Xinghuai Sun and Jianjiang Xu

    Citation: BMC Ophthalmology 2012 12:6

    Content type: Research article

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  7. The risk of visual impairment increases dramatically with age and therefore older adults should have their eyes examined at least every 1 to 2 years. Using a world-wide, population-based dataset, we sought to ...

    Authors: Claudia Vela, Elodie Samson, Maria Victoria Zunzunegui, Slim Haddad, Marie-Josée Aubin and Ellen E Freeman

    Citation: BMC Ophthalmology 2012 12:5

    Content type: Research article

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  8. The activity of melanopsin containing intrinsically photosensitive ganglion retinal cells (ipRGC) can be assessed by a means of pupil responses to bright blue (appr.480 nm) light. Due to age related factors in...

    Authors: Kristina Herbst, Birgit Sander, Henrik Lund-Andersen, Adam Elias Broendsted, Line Kessel, Michael Stormly Hansen and Aki Kawasaki

    Citation: BMC Ophthalmology 2012 12:4

    Content type: Research article

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  9. Fibrin pupillary-block glaucoma is a rare complication after cataract surgery. The treatment for this condition is still controversial, since Nd:YAG laser fibrin membranotomy tends to reocclude and laser perip...

    Authors: Hideaki Yoshino, Masaaki Seki, Jun Ueda, Takaiko Yoshino, Takeo Fukuchi and Haruki Abe

    Citation: BMC Ophthalmology 2012 12:3

    Content type: Case report

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  10. To evaluate results after seven years using prophylactic intracameral cefazolin for the prevention of endophthalmitis in cataract surgery.

    Authors: Pedro Romero-Aroca, Isabel Méndez-Marin, Merce Salvat-Serra, Juan Fernández-Ballart, Matias Almena-Garcia and Javier Reyes-Torres

    Citation: BMC Ophthalmology 2012 12:2

    Content type: Research article

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  11. The purpose of this study was to investigate current patterns of management and outcomes of intermittent distance exotropia [X(T)] in the UK.

    Authors: Deborah Buck, Christine J Powell, Jugnoo Rahi, Phillippa Cumberland, Peter Tiffin, Robert Taylor, John Sloper, Helen Davis, Emma Dawson and Michael P Clarke

    Citation: BMC Ophthalmology 2012 12:1

    Content type: Research article

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  12. The human lens is continuously exposed to high levels of light. Ultraviolet radiation is believed to play a causative role in the development of cataract. In vivo, however, the lens is mainly exposed to visibl...

    Authors: Line Kessel, Lars Eskildsen, Jesper Holm Lundeman, Ole Bjarlin Jensen and Michael Larsen

    Citation: BMC Ophthalmology 2011 11:41

    Content type: Research article

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  13. the purpose of this study was to report a binocular photic retinal injury induced by plasma arc welding and the follow-up after treatment with vitamin supplements for a month. In our study, we used different d...

    Authors: Mauro Cellini, Roberto Gattegna, Pier Giorgio Toschi, Ernesto Strobbe and Emilio C Campos

    Citation: BMC Ophthalmology 2011 11:40

    Content type: Case report

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  14. Mycotic keratitis is an important cause of corneal blindness world over including India. Geographical location and climate are known to influence the profile of fungal diseases. While there are several reports...

    Authors: Bibhudutta Rautaraya, Savitri Sharma, Sarita Kar, Sujata Das and Srikant K Sahu

    Citation: BMC Ophthalmology 2011 11:39

    Content type: Research article

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  15. Retinitis pigmentosa is characterized by the sequential loss of rod and cone photoreceptors. The preservation of cones would prevent blindness due to their essential role in human vision. Rod-derived Cone Viab...

    Authors: Emmanuelle Clérin, Nicolas Wicker, Saddek Mohand-Saïd, Olivier Poch, José-Alain Sahel and Thierry Léveillard

    Citation: BMC Ophthalmology 2011 11:38

    Content type: Technical advance

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  16. Descemet's Stripping with Automated Endothelial Keratoplasty (DSAEK) is constantly gaining popularity in the management of endothelial dysfunctions such as bullous keratopathy or Fuchs' dystrophy.

    Authors: George D Kymionis, Dimitra M Portaliou, Takeshi Ide and Sonia H Yoo

    Citation: BMC Ophthalmology 2011 11:37

    Content type: Case report

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  17. Diabetic macular oedema is the leading causes of blindness. Laser photocoagulation reduces the risk of visual loss. However recurrences are common and despite laser treatment, patients with diabetic macular oe...

    Authors: Mustapha Norlaili, Shaharuddin Bakiah and Embong Zunaina

    Citation: BMC Ophthalmology 2011 11:36

    Content type: Research article

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  18. To identify the genetic defect associated with autosomal recessive congenital cataract (ARCC), mental retardation (MR) and ARCC, MR and microcephaly present in most patients in four Tunisian consanguineous fam...

    Authors: Manèl Chograni, Myriam Chaabouni, Faouzi Mâazoul, Hedi Bouzid, Abdelhafid Kraiem and Habiba B Bouhamed Chaabouni

    Citation: BMC Ophthalmology 2011 11:35

    Content type: Research article

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  19. Glial heterotopias are rare, benign, congenital, midline, non-teratomatous extracranial glial tissue. They may masquerade as encephalocoele or dermoid cyst and mostly present in nose. Herein, we present an unu...

    Authors: Ranju Sitaula, Gulshan B Shrestha, Nabin Paudel, Sneha Shrestha and Dev N Shah

    Citation: BMC Ophthalmology 2011 11:34

    Content type: Case report

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  20. Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid re...

    Authors: Pavel Iserovich, Qiong Qin and Konstantin Petrukhin

    Citation: BMC Ophthalmology 2011 11:33

    Content type: Research article

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  21. The eMERGE (electronic MEdical Records and Genomics) network, funded by the National Human Genome Research Institute, is a national consortium formed to develop, disseminate, and apply approaches to research t...

    Authors: Carol J Waudby, Richard L Berg, James G Linneman, Luke V Rasmussen, Peggy L Peissig, Lin Chen and Catherine A McCarty

    Citation: BMC Ophthalmology 2011 11:32

    Content type: Research article

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  22. To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play...

    Authors: Tan Aik Kah, Ku Chui Yong and Ropilah Abdul Rahman

    Citation: BMC Ophthalmology 2011 11:30

    Content type: Case report

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  23. The influence of serous retinal detachment (SRD) on retinal sensitivity in patients with branch retinal vein occlusion (BRVO) and macular edema remains unclear. This is despite the frequent co-existence of SRD...

    Authors: Hidetaka Noma, Hideharu Funatsu, Tatsuya Mimura and Katsunori Shimada

    Citation: BMC Ophthalmology 2011 11:29

    Content type: Research article

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  24. Tourette syndrome is a neurologic disorder that is characterized by repetitive muscle contractions that produce stereotyped movements or sounds. Approximately 50% of individuals with TS also exhibit obsessive-...

    Authors: Artemios Kandarakis, Michael Karampelas, Vasileios Soumplis, Christos Panos, Nikolaos Makris, Stylianos Kandarakis and Dimitrios Karagiannis

    Citation: BMC Ophthalmology 2011 11:28

    Content type: Case report

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  25. To report a case with hypotony due to late leakage of the filtering bleb performed during childhood and treated surgically using human pericardium graft.

    Authors: Dimitris Papaconstantinou, Ilias Georgalas, Sergios Taliantzis, Chrysanthi Koutsandrea, Ioannis Ladas and Gerassimos Georgopoulos

    Citation: BMC Ophthalmology 2011 11:27

    Content type: Case report

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  26. Reliable data are a pre-requisite for planning eye care services. Though conventional cross sectional studies provide reliable information, they are resource intensive. A novel rapid assessment method was used...

    Authors: Srinivas Marmamula, Sreenivas R Madala and Gullapalli N Rao

    Citation: BMC Ophthalmology 2011 11:26

    Content type: Research article

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  27. Visual impairment caused by cataracts not only affects an individual's quality of life but can also have a profound impact on other important psychological factors and on the economic circumstances of individu...

    Authors: Beverley M Essue, Maree L Hackett, Andreas Mueller, Nguyen Thi Hanh Duc, Huynh Tan Phuc and Stephen Jan

    Citation: BMC Ophthalmology 2011 11:25

    Content type: Study protocol

    Published on:

  28. A noninferiority trial was conducted to evaluate the efficacy of a single evening dose of fixed-combination latanoprost 50 μg/mL and timolol 0.5 mg/mL (Xalacom®; LTFC), in Chinese patients with primary open-angle...

    Authors: Jia-Liang Zhao, Jian Ge, Xiao-Xin Li, Yu-Min Li, Yao-Hua Sheng, Nai-Xue Sun, Xing-Huai Sun, Ke Yao and Zheng Zhong

    Citation: BMC Ophthalmology 2011 11:23

    Content type: Research article

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  29. Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological hallmarks including β-amyloid (Aβ) accumulation, oxidative stress, and apoptotic cell death. The causes of AD and ...

    Authors: Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh and Othman Ghribi

    Citation: BMC Ophthalmology 2011 11:22

    Content type: Research article

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  30. The present study investigates two different treatment options for convergence insufficiency CI for a group of children with reading difficulties referred by educational institutes to a specialist eye clinic i...

    Authors: Wolfgang A Dusek, Barbara K Pierscionek and Julie F McClelland

    Citation: BMC Ophthalmology 2011 11:21

    Content type: Research article

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  31. The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a...

    Authors: Dimitrios Bizios, Anders Heijl and Boel Bengtsson

    Citation: BMC Ophthalmology 2011 11:20

    Content type: Research article

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  32. Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydri...

    Authors: Tarek A Shazly, Abdelsattar N Farrag, Asmaa Kamel and Ashraf K Al-Hussaini

    Citation: BMC Ophthalmology 2011 11:18

    Content type: Research article

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  33. To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye...

    Authors: Gail F Schwartz, Sameer Kotak, Jack Mardekian and Joel M Fain

    Citation: BMC Ophthalmology 2011 11:14

    Content type: Research article

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  34. Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular press...

    Authors: Joel M Fain, Sameer Kotak, Jack Mardekian, Jason Bacharach, Deepak P Edward, Steven Rauchman, Teresa Brevetti, Janet L Fox and Cherie Lovelace

    Citation: BMC Ophthalmology 2011 11:13

    Content type: Research article

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  35. Ophthalmic viscosurgical devices (OVDs) are widely used in phacoemulsification cataract surgery to maintain adequate intraocular space, stabilize ocular tissue during the operation and decrease the possible da...

    Authors: Marilita M Moschos, Irini P Chatziralli and Theodoros N Sergentanis

    Citation: BMC Ophthalmology 2011 11:9

    Content type: Research article

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  36. Although in vitro and in vivo laboratory studies have suggested that benzalkonium chloride (BAK) in topical ophthalmic solutions may be detrimental to corneal epithelial cells, multiple short- and long-term cl...

    Authors: Gerard Ryan Jr, Joel M Fain, Cherie Lovelace and Karl M Gelotte

    Citation: BMC Ophthalmology 2011 11:8

    Content type: Research article

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  37. To describe the methodology of the Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study III, an ongoing epidemiological study to estimate the prevalence of Diabetes and Diabetic Ret...

    Authors: Swakshyar Saumya Pal, Rajiv Raman, Suganeswari Ganesan, Chinmaya Sahu and Tarun Sharma

    Citation: BMC Ophthalmology 2011 11:7

    Content type: Study protocol

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  38. Scotopic function is an important marker of many retinal diseases and is increasingly used as an outcome measure in clinical trials, such as those investigating gene therapy for Lebers congenital amaurosis. Sc...

    Authors: Michael D Crossland, Vy A Luong, Gary S Rubin and Fred W Fitzke

    Citation: BMC Ophthalmology 2011 11:5

    Content type: Technical advance

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  39. Pituitary adenoma may present with neuro-ophthalmic manifestations and, typically, rapid tumor expansion is the result of apoplexy. Herein, we present the first case of an isolated sixth cranial nerve palsy as...

    Authors: Norman Saffra, Elizabeth Kaplow, Irina Mikolaenko, Alice Kim, Benjamin Rubin and Jafar Jafar

    Citation: BMC Ophthalmology 2011 11:4

    Content type: Case report

    Published on:

  40. The observation of cytokeratins (CK's) in mass spectrometry based studies raises the question of whether the identified CK is a true endogenous protein from the sample or simply represents a contaminant. This ...

    Authors: Mikkel Lyngholm, Henrik Vorum, Kim Nielsen, Niels Ehlers and Bent Honoré

    Citation: BMC Ophthalmology 2011 11:3

    Content type: Research article

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