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  1. The cornea is a hormone-responsive tissue that responds to changing levels of female sex hormones. This review focuses on the structural and functional changes in the human cornea associated with the hormonal ...

    Authors: Donel S. Kelly, Sabhyta Sabharwal, David J. Ramsey and Melina I. Morkin
    Citation: BMC Ophthalmology 2023 23:358
  2. Current immunotherapies are unsatisfactory against uveal melanoma (UM); however, elevated CD8+ T cell infiltration level indicates poor prognosis in UM. Here, we aimed to identify co-expressed gene networks promo...

    Authors: Chun Zhang, Jing Xiao, Luzhong Fa, Fanwen Jiang, Hui Jiang, Lin Zhou and Zhuping Xu
    Citation: BMC Ophthalmology 2023 23:354
  3. To determine the efficacy of cataract surgeries in blindness prevention programs in Chongqing.

    Authors: Yongguo Xiang, Xiaoqin Wang, Xiaochuan Cao, Fang Wei, Yu Chen, Jianchuan Ran, Zhengqin Long, Qunwu Tan, Zhenying Lai, Li Liu, Desheng Zhao, Liang Xiong, Bin Tang, Wenjuan Wan and Ke Hu
    Citation: BMC Ophthalmology 2023 23:353
  4. Ghana and Nigeria are the two countries in Africa that currently run the Doctor of Optometry (OD) program in sub-Saharan Africa (SSA). Optometrists in these countries are licensed to provide glaucoma care. Des...

    Authors: Stephen Ocansey, Edgar Ekure, Uchechukwu L. Osuagwu, Bernadine N. Ekpenyong, Godwin Ovenseri-Ogbomo, Sylvester Kyeremeh, Kelechi C. Ogbuehi, Kingsley E. Agho, Khathutshelo P. Mashige, Antor O. Ndep and Kovin S. Naidoo
    Citation: BMC Ophthalmology 2023 23:351
  5. According to previous reports, PAX6-associated foveal hypoplasia (FH) could usually be accompanied by various anterior segment anomalies including variable iris changes. This study aims to exhibit unusual phenoty...

    Authors: Yanping Yu, Hongyan Jia, Qian Ma, Ranran Zhang and Yonghong Jiao
    Citation: BMC Ophthalmology 2023 23:349
  6. Readmissions and in-hospital mortality among patients with severe vision impairment or blindness (SVI/B) has not been fully studied. We investigated hospital outcomes for adults with SVI/B in the United States.

    Authors: Michael Fatuyi, Oladipupo Anibire and Che Matthew Harris
    Citation: BMC Ophthalmology 2023 23:348
  7. Thyroid eye disease is an extrathyroidal manifestation of Graves’ disease and is associated with dry eye disease. This is the first systematic review and meta-analysis to evaluate the role of magnetic resonanc...

    Authors: Nicole Tsz Yan Wong, Ka Fai Kevin Yuen, Fatema Mohamed Ali Abdulla Aljufairi, Kenneth Ka Hei Lai, Zhichao Hu, Karen Kar Wun Chan, Clement Chee Yung Tham, Chi Pui Pang and Kelvin Kam Lung Chong
    Citation: BMC Ophthalmology 2023 23:347
  8. To evaluate if total keratometry (TK) is better than standard keratometry (K) for predicting an accurate intraocular lens (IOL) refractive outcome in virgin eyes using four IOL power calculation formulas.

    Authors: He Zhao, Xu Chen, Bo Liu, Xi Liu and Yong Liu
    Citation: BMC Ophthalmology 2023 23:346
  9. Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose co...

    Authors: Yajian Duan, Wenyi Wu, Jing Cui, Joanne Aiko Matsubara, Andrius Kazlauskas, Gaoen Ma, Xiaorong Li and Hetian Lei
    Citation: BMC Ophthalmology 2023 23:344
  10. To evaluate the efficacy of 1% and 2% rebamipide clear solution in the treatment of dry eye disease (DED).

    Authors: Youngsub Eom, So Hyang Chung, Tae-Young Chung, Jae Yong Kim, Chul Young Choi, Kyung Chul Yoon, Byung Yi Ko, Hong Kyun Kim, Mee Kum Kim, Hyung Keun Lee, Jong Suk Song, Joon Young Hyon, Kyoung Yul Seo, Jong Soo Lee and Hyo Myung Kim
    Citation: BMC Ophthalmology 2023 23:343
  11. To compare the 4-year visual outcomes of implantable collamer lens V4c (EVO-ICL) implantation and small incision lenticule extraction (SMILE) for high myopia and astigmatism.

    Authors: Wuqiang Luo, Aruma Aruma, Meiyan Li, Jing Wang, Jing Xie, Xin Xiao, Yang Shen, Lingling Niu, Xiaoying Wang and Xingtao Zhou
    Citation: BMC Ophthalmology 2023 23:341
  12. To observe the safety and effect of phacoemulsification combined with intraocular lens (IOL) implantation in patients with low corneal endothelial cell density (CD) under the low perfusion pattern with low neg...

    Authors: Yan Lin, Biting Zhou, Yihua Yao, Qin Ye, Yihua Zhu and Xiaohui Wang
    Citation: BMC Ophthalmology 2023 23:340
  13. The study was intended to confirm whether Pars Plana Vitrectomy (PPV) with Internal Limiting Membrane (ILM) peeling and intravitreal injection mouse Nerve Growth Factor(mNGF) was effective for the treatment of...

    Authors: Xiao Yu, Lingyao Wu, Ziqing Mao, Huimin Fan, Wenjia Dong and Zhipeng You
    Citation: BMC Ophthalmology 2023 23:339
  14. Ocular surface squamous neoplasia (OSSN) comprises a wide spectrum of squamous tumors, from which corneal/conjunctival intraepithelial neoplasia (CIN) is the most common one. The classic treatment is complete ...

    Authors: Beatriz Alvarado-Castillo, Francisco J. Santa Cruz-Pavlovich, Celia Gonzalez-Castillo, Isaac Alejandro Vidal-Paredes, Leonel Garcia-Benavides, Maria Elena Rosales-Gradilla and Jose Navarro-Partida
    Citation: BMC Ophthalmology 2023 23:335
  15. Cystoid macular edema is a known complication of omidenepag isopropyl usage. Omidenepag isopropyl is a selective prostanoid EP2 receptor agonist, and its association with macular edema has mainly been identifi...

    Authors: Byung-Jin Bae, Eun Min Kang and Sang Yeop Lee
    Citation: BMC Ophthalmology 2023 23:334
  16. The aim of this work is to evaluate the safety and efficacy of repeated sessions of photo-activated chromophore for keratitis-cross linking (PACK-CXL) window absorption (WA) for the treatment of resistant bact...

    Authors: Mohammed M. Mahdy Tawfeek, Hanan Mohamed Abdel Hamid Ahmed, Ashraf Bor’i and Ahmed M. Nashaat Ali Rady
    Citation: BMC Ophthalmology 2023 23:333
  17. Sarcoidosis is an inflammatory disorder in which patients frequently develop ocular manifestations that precede systemic involvement, sometimes it even presents as an ocular isolated form of the disease. The p...

    Authors: Javier Alejandro Salazar-Rodríguez, Diana Sarmiento-Forero, Claudia Hubbe-Tena and Luz-Elena Concha-del-Rio
    Citation: BMC Ophthalmology 2023 23:330
  18. Due to technological advancements, surgical invasiveness has been reduced. However, cataract surgery has been implicated in causing postoperative inflammation, including dry eye syndrome. The innate immune sys...

    Authors: Hiroki Maehara, Koki Norikawa, Keiichiro Tanaka, Yutaka Kato, Akihito Kasai, Tomoko Omori, Takeshi Machida, Hideharu Sekine and Tetsuju Sekiryu
    Citation: BMC Ophthalmology 2023 23:329
  19. Impact of low energy asymmetric spacings vs. high energy symmetric spacings on the immediate/early (postoperative day 1 (POD1)) outcomes of SmartSight lenticule extraction for myopic astigmatism with a new fem...

    Authors: Kishore Raj Pradhan and Samuel Arba Mosquera
    Citation: BMC Ophthalmology 2023 23:328
  20. Recent studies have presented inflammatory features on keratoconus (KC) and many inflammatory markers are described in the tears of patients with this disease. The KC pathogenesis is still unknown just like th...

    Authors: Junia Cabral Marques, Karina Inácio Ladislau de Carvalho, Rafaela Xavier, Walton Nosé and Luiz Vicente Rizzo
    Citation: BMC Ophthalmology 2023 23:326
  21. Retinal breaks (RB) are emergencies that require treatment to prevent progression of rhegmatogenous retinal detachment. Vitreal hyperreflective foci (VHF) representing migration of RPE cell clusters or interph...

    Authors: P. Strzalkowski, A. K. Schuster, A. Strzalkowska, J. S. Steinberg and S. Dithmar
    Citation: BMC Ophthalmology 2023 23:324
  22. To describe a condition with the following features: chronic central serous chorioretinopathy (CCSC), chorioretinal folds, scleral changes (including any of the following flattened or ‘squared off’ posterior p...

    Authors: Susan M Downes, Sonia P Mall, Saoud Al-Khuzaei, Rasmeet Chadha, Andrew Gibson, Victor Chong and Alan C. Bird
    Citation: BMC Ophthalmology 2023 23:322
  23. To determine the effect of ketorolac tromethamine 0.5% in preventing post-phacoemulsification macular thickening. This randomized clinical trial. patients randomized 1:1 to receive either topical ketorolac thr...

    Authors: Hossein Mohammad-Rabei, Hamideh Sabbaghi, Mehdi Emamverdi, Saeed Karimi, Alireza Ramezani, Homayoun Nikkhah, Bahareh Kheiri, Mehdi Yaseri, Kourosh Sheibani and Razieh Bahreini
    Citation: BMC Ophthalmology 2023 23:320
  24. Dry eye disease (DED) is caused by a persistently unstable tear film leading to ocular discomfort and is treated mainly with tear supplementation. There is emerging evidence that nicotinic acetylcholine recept...

    Authors: Bader Bashrahil, Nada Taher, Ziyad Alzahrani, Ahmed Alnabihi, Abdulaziz Aldahlawi, Mohammed Alkhathlan and Saeed Alghamdi
    Citation: BMC Ophthalmology 2023 23:319
  25. To describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments.

    Authors: Hugo Lama, Michel Pâques, Emmanuelle Brasnu, Jade Vu, Céline Chaumette, Bénédicte Dupas, Christine Fardeau, Ismaël Chehaibou, Jean-François Rouland, Guillaume Besombes, Marc Labetoulle, Antoine Labbé and Antoine Rousseau
    Citation: BMC Ophthalmology 2023 23:318
  26. Cataracts are the world’s leading cause of avoidable blindness. In low-income countries, there are high rates of poor follow-up, which makes it very difficult to monitor surgical outcomes. To address this issu...

    Authors: M. Lecumberri, C L. Moser and J. Loscos-Arenas
    Citation: BMC Ophthalmology 2023 23:317
  27. The dysfunction of optic nerve head (ONH) hemodynamics has been suggested to be involved in the pathogenesis of normal-tension glaucoma (NTG). The aim of this study was to compare vasoreactivity in the ONH, na...

    Authors: Nana Takahashi, Naoki Kiyota, Hiroshi Kunikata, Mai Yamazaki, Takayuki Nishimura, Yukihiro Shiga, Hisae Aoyagi, Miwako Shidomi, Tomohiro Tsuda, Toshihiko Ohtsuka, Takahiro Tomida and Toru Nakazawa
    Citation: BMC Ophthalmology 2023 23:316
  28. To compare vitreous angiomosaic images (VAMIs), obtained by widefield swept-source optical coherence tomographic angiography (wfSS-OCTA) and the image of fluorescein fundus angiography (FFA) in the identificat...

    Authors: Yanyan Yang, Fengjiao Li, Tingting Liu, Wanzhen Jiao and Bojun Zhao
    Citation: BMC Ophthalmology 2023 23:315
  29. To evaluate the correlations between swept-source optical coherence tomography angiography (SS-OCTA) parameters and clinical outcomes in eyes with neovascular age-related macular degeneration (nAMD) administer...

    Authors: Jong Beom Park, Kiyoung Kim, Min Seok Kang, Eung Suk Kim and Seung-Young Yu
    Citation: BMC Ophthalmology 2023 23:314
  30. To observe the distribution characteristics of corneal higher-order aberrations (HOAs) in cataract patients, and analyze the relationship of HOAs with patients’ age and ocular biometric parameters.

    Authors: Suowang Zhou, Xu Chen, Julio Ortega-Usobiaga, Hansong Zheng, Wenjing Luo, Biyue Tu and Yong Wang
    Citation: BMC Ophthalmology 2023 23:313
  31. To examine subfatin, preptin and betatrophin levels in plasma and aqueous in patients with diabetes mellitus (DM) (with and without retinopathy).

    Authors: Sabiha Güngör Kobat, Fatih Cem Gül, Fatih Çelik, Seda Liman Uzun, Mehmet Ali Kobat, Ramazan Fazıl Akkoç and Süleyman Aydın
    Citation: BMC Ophthalmology 2023 23:312

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