Figure 2

Concentration response curve of VEGF in retinal arterioles with normal tone. With intraluminal delivery over a concentration range (10^-16 – 10^-7 M) the level of contraction reduced at higher VEGF concentration, producing a significant dilatation when compared to the maximally contracted state at 10^-11 M VEGF. * Denotes a significant contraction compared to initial baseline (p < 0.05).