From: High-dose antioxidants for central serous chorioretinopathy; The randomized placebo-controlled study
Study group (group A) | Control group (group B) | p-value | Odds ratio | 95% CI | |
---|---|---|---|---|---|
Number of patients -at 1st month | 26 | 29 | 0.2 | - | - |
-at 3rd month | 26 | 25 | 1.00 | ||
-at 6th month | 16 | 14 | 0.79 | ||
-at 12th month | 7 | 7 | 1.00 | ||
VA (logMAR ± SD) -at 3rd m. | 0.09 ± 0.20 | 0.09 ± 0.09 | 0.99 | - | - |
-at 6th m. | 0.05 ± 0.06 | 0.04 ± 0.06 | 0.60 | ||
-at 12th m. | 0.04 ± 0.05 | 0.03 ± 0.05 | 0.91 | ||
CMT (microns ± SD) -at 3rd m. | 220.65 ± 94.37 | 243.84 ± 76.13 | 0.34 | - | - |
-at 6th m. | 193.20 ± 46.38 | 183.22 ± 22.59 | 0.41 | ||
-at 12th m. | 180.00 ± 15.05 | 186.22 ± 20.62 | 0.42 | ||
Patients with subretinal fluid (number of patients) | |||||
-at 1st month | 22 | 23 | 0.73 | - | - |
-at 2nd month | 13 | 14 | 0.78 | - | - |
-at 3rd month | 3 | 10 | 0.027 | 0.196 | 0.046-0.830 |
Follow-up time (m ± SD) | 9.04 ± 6.69 | 8.14 ± 8.69 | 0.67 | - | - |
FA leakage at 3rd m. (patients) | 3 | 10 | 0.027 | 0.196 | 0.046 - 0.830 |
- inkblot leakage | 2 | 9 | - | - | - |
- smokestack leakage | 1 | 1 | 0.94 | - | - |
Laser or PDT (number of patients) | 4 | 11 | 0.03 | 0.231 | 0.061 - 0.872 |
Recurrence (number of patients) | 1 | 2 | 0.29 | - | - |