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Table 1 Clinical findings and response to treatment with oral valacyclovir

From: Valacyclovir in the treatment of acute retinal necrosis

Patient

Age,Sex

Eye

Virus

Posterior extent (zone)

Time to initial response (weeks)

Time to complete resolution (weeks)

Initial BCVA

Final BCVA

Laser

Steroids

Complications

1

79, M

R

Undetermined

1

1

5

20/200

20/40

No – Zone 1

OFSI

RPE change at macula

2

39, M

L

Presumed VZV

3

1

1

20/20

20/20

No – Zone 1

No

Nil

3

82, M

R

VZV on PCR

1

1

4

20/120

CFs

Yes

Oral prednisolone

RD at 45 days

4

54, F

L

VZV on PCR

2

2

6

CFs

20/60

Yes

Oral prednisolone

Nil

5

36, M

R

HSV-2 on PCR

2

1

3

20/30

20/80

Yes

Oral prednisolone

RD at 35 days

6

36, M

L

Undetermined

3

1

3

20/20

20/16

No

No

Nil

7

33, M

L

Presumed HSV-1

1

2

5

HMs

LP

No – Zone 1

Oral prednisolone

RD at 49 days

8

30, F

R

Presumed VZV

3

1

2

20/20

20/20

Yes

No

Nil

  

L

Presumed VZV

2

1

2

20/30

20/20

Yes

No

Nil

9

81, M

L

Undetermined

2

1

6

20/20

20/40

Yes

Oral prednisolone

Nil

  1. VZV = Varicella zoster virus; HSV = Herpes simplex virus; PCR = polymerase chain reaction; BCVA = best corrected visual acuity; CFs = count fingers; HMs = hand movements; LP = perception of light; OFSI = Orbital floor corticosteroid injection; RD = retinal detachment.