Group 1 | Group 2 | OR | P-value | |
---|---|---|---|---|
mean ± SD | mean ± SD | (95% CI) | ||
n (%) | n (%) | |||
Age (years) | 59.4 ± 15.5 | 68.3 ± 12.5 | 0.95 (0.91–1.00) | 0.037 |
Sex | ||||
Male | 23 (62.2) | 10 (47.6) | 1.81 (0.61–5.34) | 0.28 |
Female | 14 (37.8) | 11 (52.4) | 1.00 | |
Diagnosis before PKP | ||||
Bullous keratopathy | 13 (35.1) | 8 (38.1) | 0.88 (0.29–2.67) | 0.82 |
Regraft | 8 (21.6) | 6 (28.6) | 0.69 (0.20–2.36) | 0.55 |
Corneal scar | 9 (24.3) | 4 (19.0) | 1.37 (0.36–5.13) | 0.64 |
Corneal dystrophy | 3 (8.1) | 1 (4.8) | 1.76 (0.17–18.13) | 0.63 |
Keratoconus | 3 (8.1) | 0 (0.0) | – | 1.00 |
Corneal ulcer | 1 (2.7) | 2 (9.5) | 0.26 (0.02–3.10) | 0.29 |
Type of surgery | ||||
PKP | 27 (73.0) | 16 (76.2) | 0.84 (0.24–2.91) | 0.79 |
PKP + ECCE + IOL | 9 (24.3) | 4 (19.0) | 1.37 (0.36–5.13) | 0.64 |
PKP + IOL suture | 1 (2.7) | 1 (4.8) | 0.56 (0.03–9.37) | 0.68 |
history of glaucoma | 8 (21.6) | 9 (42.9) | 0.37 (0.11-1.18) | 0.093 |
Previous episodes of rejection | 4 (10.8) | 4 (19.0) | 0.51 (0.11–2.32) | 0.38 |
ECD before rejection | 1669 ± 747 | 806 ± 455 | 1.002 (1.001–1.004) | 0.013 |
Interval between PKP and rejection (months) | 33.3 ± 40.0 | 28.2 ± 30.7 | 1.00 (0.99–1.02) | 0.61 |
Interval between rejection and treatment with systemic steroids (days) | 6.2 ± 5.6 | 14.5 ± 12.8 | 0.88 (0.80–0.97) | 0.0093 |
Systemic steroid | ||||
Dexamethasone phosphate | 29 (78.4) | 18 (85.7) | 0.60 (0.14–2.58) | 0.50 |
Methylprednisolone | 8 (21.6) | 3 (14.3) | 1.66 (0.39–7.07) |