Table 1 Characteristics of 8 studies on type 2 diabetes and cataract
From: Meta-analysis of the risk of cataract in type 2 diabetes
Author year | Location | Ascertainment of cataract | Type of study | Ascertainment of diabetes | Definition of cataract | Age(y) sex | Outcome | No. of case | Diabetes | No. of case | Non- diabetes | ORs (95% CI) | Adjustment for covariates | STROBE scores |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Machan 2012 [8] | French | Hospital records | Cross- sectional | Hospital records | LOCS II | <1-93 M&F | AC | 348 | 452 | 1885 | 5884 | 1.60 (1.13, 2.27) | Age, gender, smoking, systolic blood pressure, Statin use | 20 |
NS | 282 | 1546 | 1.62 (1.14, 2.29) | |||||||||||
CC | 104 | 525 | 1.37 (1.02, 1.83) | |||||||||||
PSC | 44 | 194 | 1.33 (0.90, 1.96) | |||||||||||
Tan et al. 2008 [19] | Australia | Eye examination | Cohort | Medical record or IFG test | Wisconsin Cataract Grading System | ≥49 M&F | NS | 37 | 69 | 402 | 1149 | 6.76 (1.04,14.00)* | Age, gender, smoking, myopia, and pulse pressure, sun-related skin damage, ever use of steroids, myopia, and body mass index | 21 |
CC | 32 | 95 | 443 | 1642 | 1.60 (0.78, 4.87)* | |||||||||
PSC | 15 | 112 | 162 | 1844 | 1.56 (0.72, 3.79)* | |||||||||
Rotimi et al. 2003 [18] | West African | Eye examination | Cross- sectional | IFG test | — | ≥20 M&F | AC | 373 | 831 | 35 | 191 | 3.63 (2.45, 5.37)* | Crude | 18 |
Olafsdottir et al. 2012 [7] | Sweden | Eye examination | Cross- sectional | IFG test | LOCS II score ≥ 2 | 24-93y M&F | AC | 208 | 275 | 175 | 256 | 1.44 (0.98,2.10)* | Crude | 20 |
NS | 132 | 131 | 0.88 (0.63,1.24)* | |||||||||||
CC | 180 | 131 | 1.81 (1.28,2.56)* | |||||||||||
PSC | 117 | 83 | 1.54 (1.08,2.20)* | |||||||||||
Jacques et al. 2003 [5] | USA | Eye examination | Cross- sectional | IFG test | LOCS III ≥2.5, NS; ≥1.0, CC; ≥0.5,PSC | 54-73 F | NS | NR | 31 | NR | 400 | 1.5 (0.6, 3.5) | Age, smoking , summertime sunlight exposure, and alcohol intake | 21 |
CC | 1.2 (0.6, 2.6) | |||||||||||||
PSC | 4.1 (1.8, 9.4) | |||||||||||||
Klein et al. 1995 [6] | USA | Eye examination | Cross- sectional | Medical record or IFG test | Wisconsin Cataract Grading System | 43-84 M&F | NS | 66 | 384 | 570 | 4285 | 0.93 (0.67,1.29) | Age, gender | 17 |
CC | 81 | 471 | 1.72 (1.29,2.30) | |||||||||||
PSC | 19 | 165 | 1.09 (0.66,1.78) | |||||||||||
Leske et.al. 1999 [16] | USA | Eye examination | Case- control | Medical record or IFG test | LOCS II grade ≥ 2 | 40-84 M&F | AC | 1800 | 448 | 2431 | 289# | 1.85 (1.51, 2.27) | Age, gender | 18 |
NS | 48 | 1.35 (0.89, 2.05) | ||||||||||||
CC | 229 | 201 | 1.74 (1.39, 2.18) | |||||||||||
PSC | 851 | 4 | 1.88 (0.61, 5.79) | |||||||||||
17 | ||||||||||||||
Foster et al. 2003 [15] | Singapore | Eye examination | Cross- sectional | Medical record | LOCS III ≥ 4 NS ≥ 2 for CC ≥ 2 for PSC | 40-81 M&F | AC | NR | 27 | NR | 1066 | 2.0 (0.9, 4.5) | Age, gender, body mass index and occupation. | 21 |
NS | 2.8 (0.8, 9.4) | |||||||||||||
CC | 3.1 (1.6, 6.1) | |||||||||||||
PSC | 2.2 (1.2, 4.1) |