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Table 2 Influence of latanoprost on retrobulbar hemodynamics. Influence of latanoprost on ocular perfusion. Overview of the results from CDI measurements before and one month after regular application of latanoprost: Increase of blood flow velocities were statistically not significant (n = 10). Bold printed measures were subjected to statistical testing; all other parameters were observational only.

From: Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428]

  

PSV (cms-1)

EDV (cms-1)

RI

PI

OA

before latanoprost

31.7 ± 3.1

4.6 ± 0.9

0.87 ± 0.02

2.59 ± 0.15

 

after latanoprost

39.0 ± 10.1

6.2 ± 1.2

0.83 ± 0.01

2.14 ± 0.09

CRA

before latanoprost

7.6 ± 0.6

1.5 ± 0.1

0.78 ± 0.01

1.96 ± 0.10

 

after latanoprost

8.4 ± 0.9

1.7 ± 0.1

0.79 ± 0.02

1.95 ± 0.13

SPCA

before latanoprost

8.6 ± 1.8

1.8 ± 0.2

0.74 ± 0.03

1.75 ± 0.13

 

after latanoprost

9.5 ± 1.1

2.5 ± 0.4

0.73 ± 0.03

1.60 ± 0.11

LPCA

before latanoprost

13.1 ± 1.5

2.5 ± 0.3

0.81 ± 0.02

1.96 ± 0.14

 

after latanoprost

13.0 ± 1.9

2.5 ± 0.4

0.78 ± 0.04

1.90 ± 0.21

  1. Abbreviations: OA – Ophthalmic artery, CRA – central retinal artery, SPCA – short posterior ciliary artery, LPCA – long posterior ciliary artery, PSV – peak systolic velocity, EDV – enddiastolic velocity, RI – resistive index, PI – pulsatility index.