Skip to main content

Table 4 Predictors of the average intraocular pressure in the initially treated eye (eye 1) following a uniocular trial and subsequent binocular trial of medication by multivariable linear regression.

From: Interpretation of uniocular and binocular trials of glaucoma medications: an observational case series

Cases...trial type (r 2, r2*, Intercept).

IOP, eye 1

IOP, eye 2

 

Last baseline.

During Trial.

Baseline.

Change with trial.

 

Time A

Time B

Time A

Time B – A.

 

(b, p)

(b, p)

(b, p)

(b, p)

All cases (n = 70). Trial type...

    

   ...uniocular (0.56, 0.55, 4.5)

(0.38, <0.001)

(0.29, 0.02)

(-0.005, 0.96)

(-0.10, 0.41)

   ...binocular (0.57, 0.57, 3.6)

(0.45, <0.001)

(0.07, 0.70)

(0.20, 0.16)

(0.27, 0.16)

Baseline untreated (n = 48). Trial type...

    

   ...uniocular (0.55, 0.54, 4.7)

(0.36, 0.02)

(0.26, 0.10)

(0.02, 0.89)

(-0.10, 0.56)

   ...binocular (0.56, 0.57, 3.4)

(0.39, 0.01)

(0.14, 0.51)

(0.20, 0.35)

(0.22, 0.39)

Baseline treated (n = 22). Trial type...

    

   ...uniocular (0.60, 0.59, 3.4)

(0.40, 0.006)

(0.34, 0.11)

(0.02, 0.92)

(-0.02, 0.91)

   ...binocular (0.60, 0.59, 4.3)

(0.56, 0.003)

(-0.17, 0.61)

(0.30, 0.19)

(0.44, 0.19)

  1. * r2 value for regression to predict square root of IOP, eye 1.