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Table 1 Factors associated with innate immunity and triggering into adaptive immunity

From: Wakayama symposium: interface between innate and adaptive immunity in dry eye disease

Innate defences

blinking, tear film, epithelium, secretory proteins, mucin, Langerhans cell, extracellular DNA, neutophil extracellular trap

Trigger

T-cell activation, proinflammatory cytokines, genetic polymorphisms, inappropriate control of acute inflammation, homeostasis break