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Table 2 Genotype and allele frequencies of MTHFR (C677T) variants in primary glaucoma patients and matched controls

From: Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population

Genotype/allele

PG (N = 210)

Control (N = 280)

p-value

RR

EF b /PF

N

%

N

%

CC

137

65.24

210

75.00

0.02a

0.63

0.194

CT

73

34.76

70

25.00

0.02a

1.60

0.191b

TT

0

0

0

-

-

-

-

C-allele

347

82.62

490

87.50

0.03a

0.68

0.152

T-allele

73

17.38

70

12.50

0.03a

1.47

0.163b

  1. N number of subjects, EF etiological fraction, PF preventive fraction
  2. astatistically significant
  3. bdata for EF