BMC Ophthalmology

Table 5 Genotype and allele frequencies of MTHFR (C677T) variants in PACG patients and matched controls

From: Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population

Genotype/allele	PACG (N = 66)		Control (280)		P- value	RR	EF^a/PF
Genotype/allele	N	%	N	%	P- value	RR	EF^a/PF
CC	49	74.24	210	75.00	0.87	0.961	0.007
CT	17	25.76	70	25.00	0.87	1.041	0.007^a
TT	0	-	0	-	-		-
C-allele	115	87.12	490	87.50	0.88	0.966	0.171
T-allele	17	12.88	70	12.50	0.88	1.0347	0.170^a

N number of subjects, EF etiological fraction, PF preventive fraction
^adata for EF

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ISSN: 1471-2415

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