Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population

Table 6 Genotype distribution of MTHFR C677T polymorphism in different healthy populations

Population/group studied	Sample number	Genotype frequencies % CC CT TT			Reference
Saudis	280	75	25	0	Present study
American Whites	300	47.33	42.00	10.67	[45]
American Blacks	298	77.52	19.80	2.68	[45]
Australian	288	50.69	41.32	7.99	[45]
Austrian Caucasian	211	49.76	40.76	9.48	[16]
British Caucasian	58	46.55	46.55	6.90	[46]
Canadian whites	240	56.67	37.50	5.83	[45]
Chinese	381	57.74	30.71	11.55	[47]
Chinese	878	23	49.1	27.9	[48]
Colombian	152	34.45	52.55	13.0	[49]
Dutch	188	51.60	42.02	6.38	[45]
Egyptian	149	76.50	20.10	3.40	[50]
Finish	545	53.76	42.20	4.04	[45]
French	178	40.45	47.75	11.80	[45]
German	71	63	34	3	[14]
Greek	135	30	53.85	16.15	[51]
Han Chinese North	643	31.26	48.99	19.75	[45]
Han Chinese South	430	29	53	8.1	[45]
Indian	173	79.19	19.65	1.16	[15]
Indian	70	71.43	25.71	2.86	[52]
Indian	100	69	26	5	[53]
Iranian	90	58.89	36.67	4.44	[29]
Iranian females	116	54.3	37.1	8.6	[54]
Israeli	210	57.14	34.29	8.57	[45]
Italian whites	385	33.25	51.43	15.32	[45]
Japanese	106	45.3	36.8	17.9	[28]
Jordanian	150	52.77	34.53	12.70	[55]
Kashmiri	160	75.6	16.9	7.5	[56]
Korean	100	31	50	19	[20]
Mexican Nahuas	135	5.18	42.97	51.85	[57]
Mexican Mixtecas	124	9.7	40.3	50	[57]
Mexican Mestizas	196	16.8	44.4	38.8	[57]
Pakistani Pathan	70	76	23	1	[6]
Pakistani Punjabi	73	66	34	0
Pakistani	70	81.43	18.57	0	[58]
Russian	587	53.15	39.86	6.99	[45]
Spanish whites	601	44.09	44.09	11.82	[45]
Turkish	100	51	43	6	[59]
Turkish	212	97.6	2.4	0	[60]

ISSN: 1471-2415