From: Association between polymorphisms of OGG1, EPHA2 and age-related cataract risk: a meta-analysis
Comparisons | Total | Cortical cataract | Nuclear cataract | PSC | ||||
---|---|---|---|---|---|---|---|---|
OR (95Â % CI) | P | OR (95Â % CI) | P | OR (95Â % CI) | P | OR (95Â % CI) | P | |
rs1052133 | ||||||||
 G vs. C | 1.36 (0.99, 1.87) | 0.05 | 1.50 (0.97, 2.32) | 0.07 | 1.23 (0.98, 1.55) | 0.07 | 1.26 (0.94, 1.68) | 0.12 |
 GG vs. CC | 1.88 (0.96, 3.71) | 0.07 | 2.18 (0.90, 5.28) | 0.08 | 1.45 (0.87, 2.44) | 0.16 | 1.61 (0.83, 3.09) | 0.16 |
 CG vs. CC | 1.34 (1.06, 1.70) | 0.01 | 1.43 (1.04, 1.96) | 0.03 | 1.32 (0.93, 1.86) | 0.12 | 1.22 (0.79, 1.88) | 0.37 |
 GG+CG vs. CC | 1.45 (1.16, 1.81) | 0.001 | 1.54 (1.15, 2.07) | 0.004 | 1.37 (0.99, 1.90) | 0.06 | 1.32 (0.88, 1.99) | 0.18 |
 GG vs. CG+CC | 1.65 (0.82, 3.32) | 0.16 | 1.83 (0.78, 4.29) | 0.17 | 1.18 (0.79, 1.75) | 0.43 | 1.30 (0.78, 2.17) | 0.31 |
rs7543472 | ||||||||
 T vs. C | 1.13 (0.92, 1.38) | 0.25 | 1.16 (1.01, 1.33) | 0.03 | 1.04 (0.75, 1.43) | 0.83 |  |  |
 TT vs. CC | 1.23 (0.99, 1.52) | 0.06 | 1.52 (1.05, 2.18) | 0.03 | 1.08 (0.84, 1.39) | 0.55 |  |  |
 TC vs. CC | 1.06 (0.96, 1.17) | 0.22 | 0.99 (0.82, 1.20) | 0.94 | 1.03 (0.92, 1.15) | 0.61 |  |  |
 TT+TC vs. CC | 1.08 (0.99, 1.19) | 0.10 | 1.06 (0.88, 1.27) | 0.53 | 1.04 (0.93, 1.16) | 0.49 |  |  |
 TT vs. TC+CC | 1.24 (0.90, 1.72) | 0.18 | 1.54 (1.18, 2.01) | 0.001 | 1.11 (0.72, 1.70) | 0.63 |  |  |
rs11260867 | ||||||||
 G vs. C | 0.99 (0.89, 1.11) | 0.88 | 0.89 (0.73, 1.07) | 0.20 | 1.09 (0.84, 1.40) | 0.52 |  |  |
 GG vs. CC | 1.14 (0.71, 1.83) | 0.59 | 0.62 (0.31, 1.24) | 0.18 | 1.38 (0.76, 2.49) | 0.29 |  |  |
 CG vs. CC | 1.08 (0.80, 1.47) | 0.60 | 0.66 (0.43, 1.00) | 0.05 | 1.46 (0.95, 2.23) | 0.08 |  |  |
 GG+CG vs. CC | 1.08 (0.80, 1.45) | 0.62 | 0.66 (0.44, 0.99) | 0.04 | 1.43 (0.94, 2.18) | 0.09 |  |  |
 GG vs. CG+CC | 1.16 (0.74, 1.81) | 0.52 | 1.19 (0.55, 2.59) | 0.66 | 0.95 (0.83, 1.10) | 0.50 |  |  |