Table 1 Demographics of studied patients with age-related cataract and controls

Parameter	Cataract	Controls	p-value
Age (years)	n = 103	n = 22
	71 ± 10.9	70 ± 3.4	0.35
Sex	n = 103	n = 22
Female	61 (59.2)	16 (72.7)	0.24
Male	42 (40.8)	6 (27.3)	0.24
Type of lens opacity^a	n = 100
Nuclear	93 (93.0)	-	-
Cortical	42 (42.0)	-
Posterior subcapsular	23 (23.0)	-
Mixed cataract	n = 102
Yes	51 (50.0)	-	-
No	51 (50.0)	-
Diabetes	n = 103	n = 22
Yes	20 (19.4)	-	0.02
No	83 (80.6)	22 (100)
Smoking	n = 103	n = 22
Current smoker	19 (18.4)	1 (4.5)	0.11
Ever smoker^b	69 (67.0)	12 (54.5)	0.27
Hormonal status	n = 102	n = 18
Currently on hormones	9 (8.8)	3 (16.7)	0.31
Ever on hormones^b	43 (42.2)	11 (61.1)	0.14
Menarche / Menopause
Age at menarche	n = 57	n = 12
	13 ± 1.3	13 ± 1.4	0.64
Age at menopause	n = 50	n = 13
	49 ± 6.8	50 ± 3.6	0.49
Years in menopause^c	n = 50	n = 13
	24 ± 11.7	20 ± 5.8	0.16
Reproductive years	n = 48	n = 12
	35 ± 6.9	38 ± 3.2	0.27

Data presented as absolute numbers (%) or mean ± SD. P-values were calculated with Pearson’s chi-square test for categorical parameters and Student’s t-test for continuous parameters
^a Both eyes included. Many individuals had more than one subtype, i.e. mixed cataract
^b Includes former and current users
^c Years in menopause prior to sampling

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