Skip to main content
Fig. 1 | BMC Ophthalmology

Fig. 1

From: Atypical retinal pigment epithelial defects with retained photoreceptor layers: a so far disregarded finding in age related macular degeneration

Fig. 1

Top: 2010: Initial presentation with drusenoid pigment epithelium detachment (PED). 2011: spontaneous resolution of PED. 2013: Spontaneous RPE aperture. The OCT reveals an RPE defect with SRF. The overlying photoreceptors are intact. Fundus autofluorescence (FAF) and fluorescein angiography (FA) shows hypoautofluorescence and pooling corresponding to RPE defect, respectively. 2014 Resolution of SRF after anti-VEGF treatment. Intact ellipsoid zone and ELM directly attached to the Bruch’s membrane. Enhanced choroidal signaling due to the absence of RPE is evident. Some ingrowth of iso-autofluorescent material is already notable on FAF (red, bold arrow). Also SD-OCT reveal some hyperreflective material (thin, red arrow) 2015 Ingrowth and regeneration of RPE/drusenoid material with consecutive decrease of enhanced choroidal signaling (thin, red arrow), hypoautofluorescence (red, bold arrow) and window defect Red (thin and bold) arrows denote hyperreflective and hyperFAF material, suggestive of potential ingrowth of drusenoid/RPE material

Back to article page

BMC Ophthalmology

ISSN: 1471-2415

Contact us