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Table 5 The sensitivity analysis for the adjusted hazard ratio stratified by duration of diabetes mellitus, gender and age groups

From: The elevated risk of sight-threatening cataract in diabetes with retinopathy: a retrospective population-based cohort study

Subgroups

Incidence ratea (95% CI) of Cataract

aHR1 (95% CI)

aHR2 (95% CI)

DM control

NPDR

PDR

Duration of DM (Year)

 < 2

1.47 (1.36–1.60)

3.79 (3.26–4.41)

7.76 (6.93–8.69)

2.20 (1.83–2.63)b

4.06 (3.39–4.88)b

 2–5

1.89 (1.7–2.09)

5.15 (4.36–6.08)

9.63 (8.15–11.38)

2.21 (1.79–2.73)b

3.46 (2.71–4.41)b

 ≥ 5

2.29 (1.98–2.65)

8.04 (6.56–9.87)

13.74 (11.04–17.11)

3.07 (2.33–4.03)b

4.14 (2.98–5.76)b

 P for interaction

0.3526

    

Gender subgroups

 Male

1.35 (1.23–1.47)

4.36 (3.75–5.06)

8.30 (7.37–9.34)

2.70 (2.24–3.25)b

4.00 (3.29–4.86)b

 Female

2.05 (1.9–2.21)

5.23 (4.6–5.95)

9.48 (8.36–10.75)

2.12 (1.81–2.49)b

3.81 (3.18–4.57)b

 P for interaction

0.0618

    

Age at index date

 < 40

0.22 (0.11–0.43)

0.22 (0.03–1.54)

3.96 (2.46–6.37)

1.51 (0.17–13.26)

16.99 (3.61–80.01)b

 40–59

0.73 (0.65–0.82)

2.49 (2.07–2.99)

7.57 (6.75–8.48)

2.85 (2.26–3.58)b

5.96 (4.79–7.41)b

 60–79

3.60 (3.36–3.86)

8.48 (7.53–9.57)

13.41 (11.65–15.43)

2.16 (1.86–2.51)b

2.72 (2.25–3.28)b

 ≥ 80

3.13 (2.21–4.43)

12.75 (8.22–19.76)

12.53 (6.74–23.29)

2.96 (1.51–5.81)b

2.30 (0.95–5.61)

 P for interaction

< 0.0001

    
  1. DM Diabetes mellitus, NPDR Non-proliferative diabetic retinopathy, PDR Proliferative diabetic retinopathy, aHR1 Non-proliferative diabetic retinopathy versus diabetes mellitus control, aHR2 Proliferative diabetic retinopathy versus diabetes mellitus control, aHR Adjusted hazard ratio, CI Confidential interval
  2. aIncidence rate, per 1000 person months
  3. bdenotes significant difference