Fig. 3
Differentially expressed lncRNAs modified by differential methylation were analyzed by the function of the target RNAs, combined with m6A methylation sequencing and mRNA-seq. (A) Enriched GO terms of host genes relevant to ARC pathogenesis. (B) The pie chart classify the genes involved in cell death pathway using KEGG that are controlled by lncRNA through cis mechanisms. (C) Use pie chart to classify the results in Figure A. The pie chart classify the genes involved in DNA repair pathway using KEGG that are controlled by lncRNA through cis mechanisms. The right bars represent the target genes of differentially expressed lncRNAs within several known DNA repair pathways (34%). The longer bar indicates more genes included. 66% represents unknown DNA repair pathways