Fig. 5

Representative cases of neovascular age-related macular degeneration. Optical coherence tomography (OCT) scans at baseline, after the loading phase, and at the time of the first recurrence are presented. Convolutional neural network-based fluid segmentation results and gradient-weighted class activation mapping (Grad-CAM) are also noted. The red bounding box indicates the area shown by the Grad-CAM. A OCT demonstrates the first recurrence at 1.1499 months (within three months) after the loading phase, predicting a value higher than 0.5 with a prediction of 0.6391, which is true positive. B OCT demonstrates the first recurrence at 7.3595 months (after three months) after the loading phase, predicting a value lower than 0.5 with a prediction of 0.1362, which is true negative