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Fig. 4 | BMC Ophthalmology

Fig. 4

From: Genetic detection of two novel LRP5 pathogenic variants in patients with familial exudative vitreoretinopathy

Fig. 4

The protein structures were modeled using AlphaFold2 and their conformations were evaluated via Ramachandran plots. A For the wildtype protein, 91.57% of amino acid residues were found in the favored regions. B In the p.Trp691Cys mutant, 90.08% of residues were in the favored regions. C The p.Pro1431Argfs*8 mutant showed 93.87% of its residues in the favored areas

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BMC Ophthalmology

ISSN: 1471-2415

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