Fig. 6From: Genetic detection of two novel LRP5 pathogenic variants in patients with familial exudative vitreoretinopathyComparison of active sites and H-bonds between the wildtype and mutant proteins. A. Changes in active sites in wildtype and two mutant proteins during simulation were marked in red. B. The snapshots extracted from the last frame of the MD simulation showed the intramolecular H-bonds changes in wildtype and mutants. The target residues along with H-bonds were marked in bright greenBack to article page