Fig. 8From: Genetic detection of two novel LRP5 pathogenic variants in patients with familial exudative vitreoretinopathyThe 3D binding modes of the wildtype, p.Trp691Cys, and p.Pro1431Argfs*8 systems with DKK1 protein are shown, with a focus on the docking site. The LRP5 protein is represented in purple, while the DKK1 protein is depicted in a yellow–brown colorBack to article page