Table 1 Patients’ characteristics

Age, mean (SD), years

66.3 (7.0)

66.7 (7.3)

0.790^a

Sex (female: male)

18: 11

58: 31

0.763^b

BCVA, median (IQR), LogMAR

 Baseline

0.40 (0.30, 0.50)

0.40 (0.30, 0.50)

0.534^b

 3 months

6 months

0.20

(0.10, 0.30)

0.20

(0.00, 0.30)

0.20

(0.10, 0.40)

0.10

(0.10, 0.30)

0.731^b

0.985^b

 P

< 0.001^c

< 0.001^c

< 0.001^c

< 0.001^c

CMT, mean (SD), µm

 Baseline

439.3 (70.0)

432.2 (87.0)

0.657^a

 3 months

6 months

376.6 (38.2)

370.7 (34.2)

360.0 (58.4)

344.4

(57.3)

0.156^a

< 0.05^a

 P

< 0.001^d

< 0.001^d

< 0.001^d

< 0.001^d

IRC, n, positive: negative

 Baseline

15: 14

36: 53

0.289^b

 3 months

6 months

14: 15

12: 17

41: 48

29: 60

0.755^b

0.395^b

 P

1.000^e

0.508^e

0.383 ^e

0.281^e

EIFL, n, positive: negative

 Baseline

22: 7

50: 39

0.060^b

 3 months

6 months

15: 14

13: 16

32: 57

32: 57

0.134^b

0.395^b

 P

< 0.05 ^e

< 0.01^e

< 0.001^e

< 0.001^e

ML, n, positive: negative -

18: 11

45: 44

0.283^b