Table 1 Mean IOP and mean number of hypotensive medications during follow-up in patients treated with MIMS
From: Minimally invasive micro sclerostomy (MIMS) procedure in the treatment of open-angle glaucoma
All patients | Study visit | |||||||
|---|---|---|---|---|---|---|---|---|
Baseline | Day 1 | Week 1 | Week 4 | Week 12 | Week 24 | Week 36 | Week 52 | |
N | 120 | 119 | 118 | 118 | 105 | 86 | 72 | 95 |
IOP (mmHg), mean ± SD | 27.9 ± 3.7 | 14.2 ± 7.8 | 14.4 ± 5.4 | 12.8 ± 3.9 | 14.1 ± 4.4 | 16.5 ± 6.0 | 17.6 ± 5.5 | 17.3 ± 5.3 |
P value (vs. baseline) | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
No. of medications, mean ± SD | 1.80 ± 0.8 | 0.01 ± 0.1 | 0.06 ± 0.3 | 0.06 ± 0.3 | 0.04 ± 0.2 | 0.05 ± 0.2 | 0.04 ± 0.2 | 0.27 ± 0.7 |
P value (vs. baseline) | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Stand-alone MIMS | ||||||||
N | 100 | 99 | 98 | 99 | 87 | 71 | 58 | 78 |
IOP (mmHg), mean ± SD | 28.2 ± 3.9 | 13.3 ± 7.5 | 14.2 ± 5.8 | 13.1 ± 4.1 | 14.5 ± 4.6 | 17.3 ± 6.2 | 18.3 ± 5.9 | 17.7 ± 5.8 |
P value (vs. baseline) | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
No. of medications, mean ± SD | 1.88 ± 0.8 | 0.00 ± 0.0 | 0.07 ± 0.4 | 0.07 ± 0.4 | 0.04 ± 0.2 | 0.04 ± 0.2 | 0.03 ± 0.2 | 0.30 ± 0.7 |
P value (vs. baseline) | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Phacoemulsification-MIMS | ||||||||
N | 20 | 20 | 20 | 19 | 18 | 15 | 14 | 17 |
IOP (mmHg), mean ± SD | 26.7 ± 2.6 | 18.8 ± 7.8 | 15.5 ± 3.2 | 11.4 ± 2.0 | 12.4 ± 2.3 | 12.9 ± 2.6 | 14.8 ± 2.1 | 15.8 ± 1.9 |
P value (vs. baseline) | – | – | – | – | – | – | – | < 0.001 |
No. of medications, mean ± SD | 1.40 ± 0.6 | 0.05 ± 0.2 | 0.00 ± 0.0 | 0.00 ± 0.0 | 0.00 ± 0.0 | 0.00 ± 0.0 | 0.00 ± 0.0 | 0.12 ± 0.5 |
P value (vs. baseline) | – | – | – | – | – | – | – | < 0.001 |