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Table 3 Demographics and clinical presentation of 8 patients with ophthalmic AXG

From: Clinicopathological study of ophthalmic cutaneous and mucocutaneous non-langerhans cell histiocytic lesions

Case

Age range

Gender

Clinical Presentation

Duration of Symptoms

Treatment

Eyelid lesions

   

1

50-55

Female

Bilateral Upper and lower eyelid large yellow lesions resembling xanthelasma

13 months

Surgical excision with full thickness skin graft

2

60-65

Male

Right lower lid 8 × 9 mm nodular lesion with central ulceration, madarosis, and orbital involvement

1 week

Surgical excision alone after multiple reoccurrences

3

40-45

Male

Bilateral Upper and Lower yellow nodules

7 years

Surgical excision with full thickness skin graft + intralesional steroids/Avastin + Methotrexate treatment

4

40-45

Female

Right lower eyelid margin 3 × 4 mm globular firm mass attached to the tarsus

3 months

Surgical Excision alone

Conjunctival/Limbal lesions

 

1

35-40

Male

Right sub-conjunctival 3 × 3 mm yellow firm non-mobile nodule

24 weeks

Surgical excision alone

2

40-45

Male

Right corneal vascularized, keratinized lesion with anterior staphyloma involving entire cornea

2.6 years

Surgical excision + PKP for corneal scarring

3

30-35

Female

Right limbal 4 × 3 mm elevated orange mass at supero-nasal cornea invading all layers of the stroma

8 months

Surgical excision + AMT

4

25-30

Male

Right supero-nasal limbal 9 × 6 mm orange mass with vascularization

3 weeks

Surgical excision + AMT

  1. PKP: Penetrating keratoplasty; AMT: Amniotic membrane transplant