Optical coherence tomography biomarkers as outcome predictors to guide dexamethasone implant use in patients with iERM: a randomized controlled trial

Luan, Rong; Wang, Manqiao; Gong, Yi; Liu, Boshi; Huang, Xinyuan; Wang, Jie; Sun, Shuo; Zhao, Jinzhi; Chen, Xiteng; Yang, Qianhui; Liu, Juping; Shao, Yan; Li, Xiaorong

doi:10.1186/s12886-024-03429-2

Table 2 Baseline predictors of best-corrected visual acuity outcome after surgery

From: Optical coherence tomography biomarkers as outcome predictors to guide dexamethasone implant use in patients with iERM: a randomized controlled trial

	Control Group				DEX Group				P_time*group	P_time	P_group
	1 day	1 week	1 month	3 months	1 day	1 week	1 month	3 months	P_time*group	P_time	P_group
Preoperative CMT
<400 μm	0.301 ± 0.035	0.244 ± 0.039	0.199 ± 0.048	0.192 ± 0.038	0.402 ± 0.058	0.209 ± 0.036	0.165 ± 0.041	0.108 ± 0.042	0.253	< 0.001	0.767
≥400 μm	0.620 ± 0.070	0.457 ± 0.068	0.379 ± 0.069	0.315 ± 0.053	0.561 ± 0.090	0.450 ± 0.066	0.300 ± 0.064	0.288 ± 0.075	0.486	< 0.001	0.619
CME
Absent	0.396 ± 0.049	0.298 ± 0.042	0.234 ± 0.046	0.208 ± 0.042	0.423 ± 0.056	0.270 ± 0.037	0.172 ± 0.032	0.139 ± 0.037	0.649	< 0.001	0.498
Present	0.706 ± 0.079	0.522 ± 0.093	0.459 ± 0.100	0.384 ± 0.072	0.798 ± 0.137	0.638 ± 0.126	0.565 ± 0.072	0.482 ± 0.132	0.977	0.001	0.428
MME
Absent	0.345 ± 0.037	0.263 ± 0.035	0.199 ± 0.044	0.183 ± 0.037	0.383 ± 0.060	0.289 ± 0.048	0.188 ± 0.036	0.135 ± 0.049	0.438	< 0.001	0.936
Present	0.708 ± 0.084	0.538 ± 0.081	0.458 ± 0.078	0.377 ± 0.055	0.620 ± 0.086	0.381 ± 0.076	0.295 ± 0.073	0.267 ± 0.074	0.547	< 0.001	0.168
HRF
Absent	0.417 ± 0.046	0.311 ± 0.044	0.246 ± 0.044	0.227 ± 0.039	0.467 ±0.081	0.349 ± 0.060	0.277 ± 0.052	0.271 ± 0.060	0.981	< 0.001	0.552
Present	0.602 ± 0.098	0.452 ± 0.090	0.389 ± 0.096	0.313 ± 0.068	0.500 ± 0.061	0.301 ± 0.052	0.176 ± 0.048^*	0.104 ± 0.040^*	0.746	< 0.001	0.043
EIFL
Absent	0.389 ± 0.044	0.321 ± 0.044	0.275 ± 0.044	0.264 ± 0.042	0.409 ± 0.062	0.289 ± 0.053	0.190 ± 0.046	0.165 ± 0.050	0.366	< 0.001	0.407
Present	0.722 ± 0.109	0.472 ± 0.110	0.362 ± 0.118	0.253 ± 0.058	0.641 ± 0.089	0.411 ± 0.063	0.328 ± 0.072	0.260 ± 0.091	0.862	< 0.001	0.701
DRIL
Absent	0.357 ± 0.048	0.284 ± 0.041	0.213 ± 0.041	0.201 ± 0.032	0.341 ± 0.048	0.227 ± 0.043	0.170 ± 0.051	0.136 ± 0.056	0.849	< 0.001	0.377
Present	0.693 ± 0.080	0.492 ± 0.089	0.439 ± 0.061	0.353 ± 0.072	0.637 ± 0.082	0.446 ± 0.061	0.310 ± 0.056	0.271 ± 0.065	0.701	< 0.001	0.377
IS-OS continuity
continuous	0.446 ± 0.057	0.356 ± 0.051	0.310 ± 0.049	0.256 ± 0.035	0.405 ± 0.056	0.268 ± 0.040	0.170 ± 0.041	0.138 ± 0.046	0.521	< 0.001	0.081
disrupted	0.685 ± 0.055	0.425 ± 0.041	0.291 ± 0.043	0.305 ± 0.043	0.709 ± 0.082	0.514 ± 0.062	0.434 ± 0.025	0.372 ± 0.078	0.327	< 0.001	0.123

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