Orbital glomus tumor in an Asian patient
© Chang et al.; licensee BioMed Central Ltd. 2012
Received: 13 June 2012
Accepted: 16 November 2012
Published: 5 December 2012
This report describes a recurrent orbital glomus tumor in an Asian patient.
A healthy 50-year-old Korean man had progressive right exophthalmos and a soft mass on his right lower lid for 6 months. We evaluated the mass using CT and MRI, and performed excisional biopsy and pathologic examination. Pathologically, the mass was a glomus tumor. Although proptosis of the right eye decreased, one month after surgery it increased to almost the same level as before surgery.
This is the first report of an Asian patient with an orbital glomus tumor that demonstrated rapid re-growth after incision without pain or visual problems.
KeywordsOrbital glomus tumor Asian patients Recur Rapid growth Painless
Glomus tumors are rare, benign neoplasms of the glomus body, a specialized thermoregulatory arteriovenous structure. These tumors most commonly present in the dermis of the digits and palms,  and rarely in the orbit. We describe the unique features of a large orbital glomus tumor that developed and re-grew rapidly in an Asian patient.
Characteristics of previously reported orbital glomus tumors
Neufeld et al. (1994)
2.4x1.4x1.6 cm Solid homogenous (CT)
Fully encapsulates with a purple-blue color
Glomus cell tumor proper
Shields et al. (2006)
Blue-gray subconjunctival lesion involving medial and superior rectus muscles
Pribila et al. (2010)
Painful burning sensation
Limited abductionand supraduction
irregular, lobulated, 2.6x3.5x3.3 cm isointense to muscle on T1 weighting imaging, which was diffusely enhanced with gadolinium (MRI)
Extensive bleeding and friable
Both glomus cell tumor proper and glomangioma
Ulivieri et al.
A well-defined circumscribed mass,displacing the globe and lateral rectus muscle inferotemporally
Excision (Kronlein approach)
smooth marginated, lobulated 2.8x3.3x3.2 cm, located intraconally and extraconally, low signals on T1 weighting imaging, which were moderately enhanced with gadolinium (MRI)
Reddish and pinkish colored multilobulated mass
Glomus cell tumor proper
- Weiss SW GJ: Perivascular Tumors in Soft Tissue Tumors. Enzinger and Weiss' soft tissue tumors. Edited by: Weiss SW, Goldblum JR, Enzinger FM. 2008, Philadelphia, PA: Mosby Elsevier, 751-767. 5Google Scholar
- Neufeld M, Pe'er J, Rosenman E, Lazar M: Intraorbital glomus cell tumor. Am J Ophthalmol. 1994, 117 (4): 539-541.View ArticlePubMedGoogle Scholar
- Shields JA, Eagle RC, Shields CL, Marr BP: Orbital-conjunctival glomangiomas involving two ocular rectus muscles. Am J Ophthalmol. 2006, 142 (3): 511-513. 10.1016/j.ajo.2006.03.054.View ArticlePubMedGoogle Scholar
- Pribila JT, Cornblath WT, Ramocki JM, Marentette LJ, Flint A, Elner VM: Glomus cell tumor of the orbit. Arch Ophthalmol. 2010, 128 (1): 144-146. 10.1001/archophthalmol.2009.359.View ArticlePubMedGoogle Scholar
- Ulivieri S, Toninelli S, Giorqio A, Fruschelli M, Miracco C, Oliveri G: Orbital glomangioma. Orbit. 2012, 31 (4): 216-218. 10.3109/01676830.2012.678546.View ArticlePubMedGoogle Scholar
- Folpe AL, Fanburg-Smith JC, Miettinen M, Weiss SW: Atypical and malignant glomus tumors: analysis of 52 cases, with a proposal for the reclassification of glomus tumors. Am J Surg Pathol. 2001, 25 (1): 1-12. 10.1097/00000478-200101000-00001.View ArticlePubMedGoogle Scholar
- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2415/12/62/prepub
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.