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Table 3 IOP changes from baseline to week 12 by diagnosis and gender, mean ± SD (ITT population)

From: Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination

  

Diagnosis

IOP

All

N = 383

OAG

N = 208

OHT

N = 161

Both

N = 14

Baseline, mmHg

22.19 ± 2.16

21.95 ± 2.27

22.40 ± 1.97

23.36 ± 2.19

Week 12, mmHg

16.77 ± 2.62

16.61 ± 2.77

17.00 ± 2.48

16.64 ± 1.67

Change from baseline to week 12, mmHg

-5.42 ± 2.71

-5.34 ± 2.76

-5.40 ± 2.60

-6.71 ± 2.95

Change from baseline to week 12, %

-24.10 ± 11.35

-24.06 ± 11.70

-23.82 ± 10.92

-28.07 ± 10.86

 

Gender

 
 

Male

N = 179

 

Female

N = 204

 

Baseline, mmHg

22.29 ± 2.13

 

22.10 ± 2.20

 

Week 12, mmHg

16.53 ± 2.55

 

16.99 ± 2.67

 

Change from baseline to week 12, mmHg

-5.76 ± 2.77

 

-5.11 ± 2.62

 

Change from baseline to week 12, %

-25.51 ± 11.38

 

-22.87 ± 11.20

 
  1. Both = OAG and OHT; IOP = intraocular pressure; ITT = intent-to-treat population;
  2. OAG = open-angle glaucoma; OHT = ocular hypertension; SD = standard deviation.