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  1. Content type: Research article

    This study is aim to compare the clinical effectiveness between the two most prominent dry eye disease (DED)-specific eye drops, 0.05% cyclosporine (CN) and 3% diquafosol (DQ).

    Authors: Chang Hyun Park, Hyung Keun Lee, Mee Kum Kim, Eun Chul Kim, Jae Yong Kim, Tae-im Kim, Hong Kyun Kim, Jong Suk Song, Kyung Chul Yoon, Do Hyung Lee, Tae-Young Chung, Chul Young Choi and Hyun Seung Kim

    Citation: BMC Ophthalmology 2019 19:131

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  2. Content type: Research article

    Nerve growth factor (NGF), produced by Müller cells, and internal limiting membrane (ILM) have fundamental roles in the development of full-thickness macular hole (FTMH). However, the potential crosstalk betwe...

    Authors: Luyi Zhang, Xiaoxia Li, Xiaoqin Lin and Miaoqin Wu

    Citation: BMC Ophthalmology 2019 19:130

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  3. Content type: Research article

    To evaluate the retinal function before and soon after an intravitreal injection of an anti-vascular endothelial growth factor (anti-VEGF) agents.

    Authors: Gaku Terauchi, Kei Shinoda, Hiroyuki Sakai, Makoto Kawashima, Celso Soiti Matsumoto, Atsushi Mizota and Yozo Miyake

    Citation: BMC Ophthalmology 2019 19:129

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  4. Content type: Research article

    To evaluate the efficacy of swept –source optical coherence tomography angiography (SS-OCTA) in grading macular perfusion in retinal vein occlusion.

    Authors: Magdy Moussa, Mahmoud Leila, Amr Saad Bessa, Mohamed Lolah, Mohsen Abou Shousha, Hazem Medhat El Hennawi and Tarek Abdelrazek Hafez

    Citation: BMC Ophthalmology 2019 19:127

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  5. Content type: Research article

    To delineate the characteristics of complicated familial exudative vitreoretinopathy (FEVR) patients diagnosed before surgery or intra−/post-operatively and to analyze the risk factors for the diagnostic timing.

    Authors: Fengjie Xia, Jiao Lyu, Ping Fei and Peiquan Zhao

    Citation: BMC Ophthalmology 2019 19:126

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  6. Content type: Research article

    To assess the changes in individual retinal layer thickness and visual function associated with gains in visual acuity after an intravitreal conbercept injection in the diabetic macular edema (DME) on spectral...

    Authors: Yupeng Xu, Yuan Qu, Yan Suo, Jian Gao, Xia Chen, Kun Liu and Xun Xu

    Citation: BMC Ophthalmology 2019 19:123

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  7. Content type: Case report

    Anterior megalophthalmos is a rare congenital disease which mainly features enlargement of the anterior segment. Cataract surgeries in anterior megalophthalmos can be challenging due to the anatomical anomalie...

    Authors: Ao Miao, Keke Zhang, Jifeng Yu, Wenwen He, Yi Lu and Xiangjia Zhu

    Citation: BMC Ophthalmology 2019 19:122

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  8. Content type: Research article

    High myopia with shallow anterior chamber depth (ACD less than 2.8 mm) is not rare. This observational study aims to evaluate visual outcomes after implantation of the Visian Implantable Collamer Lens with a c...

    Authors: Lingling Niu, Huamao Miao, Tian Han, Lan Ding, Xiaoying Wang and Xingtao Zhou

    Citation: BMC Ophthalmology 2019 19:121

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  9. Content type: Research article

    To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 m...

    Authors: Dorota Borowicz, Katarzyna Nowomiejska, Dominika Nowakowska, Agnieszka Brzozowska, Mario D Toro, Teresio Avitabile, Anselm G. Jünemann and Robert Rejdak

    Citation: BMC Ophthalmology 2019 19:118

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  10. Content type: Case report

    Rhinosinusitis is a common condition which may present with complications commonly involving the orbit and the intracranial space. Loss of vision in the absence of clinical or radiological signs of involvement...

    Authors: John Kutsukutsa, Nthabeleng Rankhethoa, Jaivani Sharvani Pillay, Johannes Frederik De Jager, Zaynah Dangor and Yesholata Mahabeer

    Citation: BMC Ophthalmology 2019 19:117

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  11. Content type: Research article

    The present study aims to investigate an automated qualitative and quantitative assessment system (Automated Quantification of After-Cataract [AQUA II]) of posterior capsule opacification (PCO) in high-resolut...

    Authors: Martin Kronschläger, Hannes Siegl, Axel Pinz, Christoph Feichtenhofer, Wolf Buehl, Nino Hirnschall and Oliver Findl

    Citation: BMC Ophthalmology 2019 19:114

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  12. Content type: Research article

    We aimed to investigate the deformation of the outer nuclear layer using optical coherence tomography in patients with epiretinal membrane (ERM) and its relationship with metamorphopsia.

    Authors: Seiji Takagi, Shigeki Kudo, Hideo Yokota, Masahiro Akiba, Michiko Mandai, Yasuhiko Hirami, Masayo Takahashi, Yasuo Kurimoto and Masahiro Ishida

    Citation: BMC Ophthalmology 2019 19:113

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  13. Content type: Research article

    Oxidative stress (OS) is an essential factor in the pathogenesis of branch retinal vein occlusion (BRVO). Studies have demonstrated the role of hydrogen gas in the regulation of OS. This study was designed to ...

    Authors: Pan Long, Weiming Yan, Mengshan He, Qianli Zhang, Zhe Wang, Manhong Li, Junhui Xue, Tao Chen, Jing An and Zuoming Zhang

    Citation: BMC Ophthalmology 2019 19:112

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  14. Content type: Case report

    To report a case of unilateral peripheral cone dysfunction syndrome and evaluate the associated clinicopathological changes using swept-source optical coherence tomography (SS-OCT).

    Authors: Tetsuya Hasegawa, Soichi Tetsuka, Aya Yamaguchi, Chieko Kobashi, Tomomi Sato, Yoshiaki Tanaka and Akihiro Kakehashi

    Citation: BMC Ophthalmology 2019 19:111

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  15. Content type: Research article

    The purpose of this case series was to further characterize proteasome inhibitor associated chalazia and blepharitis, to investigate outcomes of different management strategies, and to propose a treatment algo...

    Authors: Bonnie A. Sklar, Kalla A. Gervasio, Siyang Leng, Arnab Ghosh, Ajai Chari and Albert Y. Wu

    Citation: BMC Ophthalmology 2019 19:110

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  16. Content type: Case report

    The involvement of choroidal lesions in acute macular neuroretinopathy (AMN) is not yet fully understood. We quantitatively examined sequential changes in the morphology and circulation hemodynamics of the cho...

    Authors: Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Yuka Hasegawa and Susumu Ishida

    Citation: BMC Ophthalmology 2019 19:109

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  17. Content type: Research article

    To investigate, using optical coherence tomography angiography (OCT-A), changes in perfusion density and in the foveal avascular zone (FAZ) in eyes with idiopathic vitreomacular traction (VMT) after ocriplasmi...

    Authors: Lorenzo Iuliano, Giovanni Fogliato, Roberta Colombo, Riccardo Sacconi, Giuseppe Querques, Francesco Bandello and Marco Codenotti

    Citation: BMC Ophthalmology 2019 19:108

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  18. Content type: Research article

    Femtosecond laser–assisted LASIK (FS-LASIK) can make ultra-thin corneal flap accurately. MEL 90 excimer laser provides Triple-A ablation mode, which significantly reduces the amount of corneal tissue cutting. ...

    Authors: Kai Li, Chuan-Wei Zhang, De-Jian Hong, Jing Wu and Yi-Shuo Yao

    Citation: BMC Ophthalmology 2019 19:107

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  19. Content type: Research article

    Myopia is a common visual disorder with increasing prevalence. Halting progression of myopia is critical, as high myopia can be complicated by a number of vision-compromising conditions.

    Authors: Efthymia Prousali, Anna-Bettina Haidich, Andreas Fontalis, Nikolaos Ziakas, Periklis Brazitikos and Asimina Mataftsi

    Citation: BMC Ophthalmology 2019 19:106

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  20. Content type: Research article

    To present the follow-up outcomes of a modified technique of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support.

    Authors: Shuang Ni, Wei Wang, Xiang Chen, Xingdi Wu, Suhong He, Yajuan Ma and Wen Xu

    Citation: BMC Ophthalmology 2019 19:105

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  21. Content type: Case report

    To report the case of a 31-year-old patient with Hand, Foot and Mouth Disease (HFMD) and concurrent acute monocular maculopathy, and to describe multimodal imaging findings never before described including opt...

    Authors: Michael Reich, Bertan Cakir, Stevan Cvetkoski, Stefan J. Lang, Andreas Stahl, Thomas Ness, Hansjürgen Agostini and Clemens Lange

    Citation: BMC Ophthalmology 2019 19:104

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  22. Content type: Research article

    To describe the effects of intravitreal bevacizumab injection (IVB) and/or transpupillary thermotherapy (TTT) in the treatment of small pigmented choroidal lesions with subfoveal fluid (SFF), and to investigat...

    Authors: Junwon Lee, Hee Jung Kwon, Min Kim, Christopher Seungkyu Lee and Sung Chul Lee

    Citation: BMC Ophthalmology 2019 19:103

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  23. Content type: Research article

    Lens-induced myopization in guinea pigs has been used as model for the process of myopization in humans. It has not been explored yet whether the change in globe shape in eyes undergoing myopization is similar...

    Authors: Li Dong, Xu Han Shi, Yi Kun Kang, Wen Bin Wei, Ya Xing Wang and Jost B. Jonas

    Citation: BMC Ophthalmology 2019 19:102

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  24. Content type: Case report

    Cancer-associated retinopathy (CAR) is associated with various malignancies, including small cell lung cancer (SCLC). It is difficult to recognize, but prompt diagnosis is crucial for the patient, as retinopat...

    Authors: William Carrera, Kathy A. Tsamis and Rajiv Shah

    Citation: BMC Ophthalmology 2019 19:101

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  25. Content type: Case report

    The optimal treatment of serpiginous choroiditis is not established. While recent reports indicate the efficacy of adalimumab, there is limited evidence. We present a case of serpiginous choroiditis refractory...

    Authors: Kazunori Noda, Akio Oishi, Akihito Uji, Saori Tanaka and Akitaka Tsujikawa

    Citation: BMC Ophthalmology 2019 19:95

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  26. Content type: Research article

    The exact pathogenesis of idiopathic choroidal neovascularization (ICNV) remains unclear. Cytokine-mediated inflammation has been thought to be involved in the pathophysiology of ICNV. The purpose of this stud...

    Authors: Shenchao Guo, Houfa Yin, Mingjie Zheng, Yizhen Tang, Bing Lu, Xinyi Chen, Qiuli Fu, Zhenwei Qin, Danni Lyu, Qiaomei Tang, Lifang Zhang, Jian Ma, Li Zhang and Xiaoyun Fang

    Citation: BMC Ophthalmology 2019 19:94

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  27. Content type: Technical advance

    The study aimed to assess the role of intraoperative mitomycin-C (MMC) application during hyperopic LASIK correction (+ 1.00 D to + 6.00 D) by examining topographic corneal changes and incidence of regression ...

    Authors: Ehab M. Moawad, Ahmed A. Abd Elghany, Amr A. Gab-Alla, Osama M. Elbassiouny and Mohsen S. Badawy

    Citation: BMC Ophthalmology 2019 19:93

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  28. Content type: Research article

    Retinopathy of prematurity (ROP), the primary cause of blindness in children, is a potential complication for 7.7% of live births in Mexico. Given that less than one-third of all neonatal intensive care units ...

    Authors: Roger Acevedo-Castellón, Paulina Ramírez-Neria and Renata García-Franco

    Citation: BMC Ophthalmology 2019 19:91

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  29. Content type: Research article

    The purpose of this study was to perform a systematic review of the current literature on simulator-based training in vitreoretinal surgery (VRS). We examined the results regarding simulated VRS and provided a...

    Authors: Rasmus Christian Rasmussen, Jakob Grauslund and Anna Stage Vergmann

    Citation: BMC Ophthalmology 2019 19:90

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  30. Content type: Research article

    The evidence on diagnostic test accuracy (DTA) of diabetic retinopathy (DR) screening utilising photographic studies by non-ophthalmologist personnel in low and middle-income country (LMIC) settings is scarce....

    Authors: Mapa Mudiyanselage Prabhath Nishantha Piyasena, Jennifer L. Y. Yip, David MacLeod, Min Kim and Venkata S. Murthy Gudlavalleti

    Citation: BMC Ophthalmology 2019 19:89

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  31. Content type: Research article

    Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) are frequently used to treat myopia. However, little is known about the impact on recovery of these ...

    Authors: Ting Liu, Guanting Lu, Kaijian Chen, Qiuxia Kan and Ji Bai

    Citation: BMC Ophthalmology 2019 19:88

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  32. Content type: Research article

    To report the clinical course and outcomes of adjunctive dexamethasone implants in patients with atopic dermatitis (AD) and retinal detachment (RD) undergoing vitrectomy and silicone oil tamponade.

    Authors: Ah Ran Cho and Young Hee Yoon

    Citation: BMC Ophthalmology 2019 19:86

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  33. Content type: Technical advance

    To report a surgical technique and the surgical outcomes of individualized penetrating keratoplasty (PK) using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers.

    Authors: Guozhen Niu, Qi Zhou, Xinyu Huang, Sangsang Wang, Juan Zhang, Yushan Zhang and Yanlong Bi

    Citation: BMC Ophthalmology 2019 19:85

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  34. Content type: Research article

    To investigate the relationship between the foveal outer nuclear layer (ONL) thickness in the active and resolved phases of central serous chorioretinopathy (CSC), and its possible association with optical coh...

    Authors: Jia Yu, Yuan Lei, Qing Chang, Gezhi Xu, Xiaofeng Ye, Lei Li and Chunhui Jiang

    Citation: BMC Ophthalmology 2019 19:84

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  35. Content type: Research article

    To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand.

    Authors: Suthasinee Kumluang, Lily Ingsrisawang, Sermsiri Sangroongruangsri, Usa Chaikledkaew, Tanapat Ratanapakorn, Paisan Ruamviboonsuk, Wongsiri Taweebanjongsin, Janejit Choovuthayakorn, Somanus Thoongsuwan, Prut Hanutsaha, Kittisak Kulvichit, Thitiporn Ratanapojnard, Warapat Wongsawad, Pattara Leelahavarong and Yot Teerawattananon

    Citation: BMC Ophthalmology 2019 19:82

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