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  1. Content type: Research article

    To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery.

    Authors: Shixu Li, Yiping Hu, Ran Guo, Yushuang Shao, Jiangyue Zhao, Jinsong Zhang and Jing Wang

    Citation: BMC Ophthalmology 2019 19:59

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  2. Content type: Research article

    Convergence and accommodative insufficiency represent the main cause of complaints during close visual work and can reduce visual performance and comfort. Knowing their prevalence among schoolchildren is funda...

    Authors: Amélia F. Nunes, Pedro M. L. Monteiro, Francisco B. P. Ferreira and António S. Nunes

    Citation: BMC Ophthalmology 2019 19:58

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  3. Content type: Research article

    Cataract patients were always excluded from studies on ageing of colour vision; thus, effect of age-related cataracts on deterioration of colour perception has not been analysed. In present study, impacts of a...

    Authors: Mingxin Ao, Xuemin Li, Weiqiang Qiu, Zhiqiang Hou, Jie Su and Wei Wang

    Citation: BMC Ophthalmology 2019 19:56

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  4. Content type: Research article

    To demonstrate that the Corvis ST could be used to quantify the biomechanical parameters of the orbital soft tissues by measuring and comparing whole eye movement (WEM) using the Corvis in normal eyes and in e...

    Authors: Ho Sik Hwang, Eun Chul Kim, Man Soo Kim and Suk-Woo Yang

    Citation: BMC Ophthalmology 2019 19:53

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  5. Content type: Research article

    To investigate structural and functional correlations in glaucoma patients using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT)-derived parameters.

    Authors: Flavio S. Lopes, Igor Matsubara, Izabela Almeida, Syril K. Dorairaj, Roberto M. Vessani, Augusto Paranhos Jr and Tiago S. Prata

    Citation: BMC Ophthalmology 2019 19:52

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  6. Content type: Research article

    Migraine is linked to endothelial dysfunction and is considered to be a systemic vasculopathy. Interestingly, systemic vascular diseases also occur in glaucoma patients and are considered to be vascular risk f...

    Authors: Jehn-Yu Huang, Chien-Chia Su, Tsing-Hong Wang and I-Ju Tsai

    Citation: BMC Ophthalmology 2019 19:50

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  7. Content type: Research article

    Many patients voice concerns regarding poor night vision, even when they see 20/20 or better in the exam room. During mesopic and scotopic conditions the pupil size increases, increasing the effects on visual ...

    Authors: Nicole M. Putnam, Balamurali Vasudevan, Andre Juarez, Cam Tu Le, Kristine Sam, Pablo de Gracia and Allissun Hoppert

    Citation: BMC Ophthalmology 2019 19:49

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  8. Content type: Research article

    Core Outcome Sets (COS) are defined as the minimum sets of outcomes that should be measured and reported in all randomised controlled trials to facilitate combination and comparability of research. The aim of ...

    Authors: Samia Al Jabri, Jamie Kirkham and Fiona J. Rowe

    Citation: BMC Ophthalmology 2019 19:47

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  9. Content type: Research article

    This study sought to compare the visual quality between intraocular collamer lens (EVO-ICL) implantation and small-incision lenticule extraction (SMILE) and determine the appropriate surgical method to treat p...

    Authors: Qin Qin, Lianyun Bao, Liping Yang, Zifang He and Zhenping Huang

    Citation: BMC Ophthalmology 2019 19:21

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  10. Content type: Research article

    To investigate the occurrence of ciliochoroidal detachment (CCD), its risk factors and its impact on the success rate after Ahmed glaucoma valve (AGV) implantation.

    Authors: Lin Fu, Yau Kei Chan, Li Nie, Qi Dai, Zhenbin Qian, Kendrick Co Shih, Jimmy Shiu Ming Lai, Rong Huang and Weihua Pan

    Citation: BMC Ophthalmology 2019 19:46

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  11. Content type: Research article

    To study the efficacy of the biodegradable collagen implant Ologen® as an adjuvant in phaco-viscocanalostomy in patients with coexisting cataract and primary open angle glaucoma.

    Authors: Ahmed A. M. Gad, Bahaa-Eldin Hasan Abdulhalim, Ayman Lotfy, Ayman Mohamed Abdelrahman and Ahmed Samir Ahmed

    Citation: BMC Ophthalmology 2019 19:45

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  12. Content type: Research article

    A study was conducted to evaluate the choroidal thickness (CT) and retinal thickness (RT) in paediatric patients with hypoalbuminaemia caused by nephrotic syndrome (NS). We also studied the correlation between...

    Authors: Wenbo Zhang, Yadi Zhang, Lei Kang, Xiaopeng Gu, Hailong Wu and Liu Yang

    Citation: BMC Ophthalmology 2019 19:44

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  13. Content type: Research article

    To investigate the expression of Matrix Metalloproteinases 2 and aquaporin-1 in corneoscleral junction and explore the mechanism of trabecular damageafter angle-closure.

    Authors: Yaqin Jiang, Canwei Zhang, Jianli Ma, Luping Wang, Jing Gao, Jiantao Ren, Wei He, Sheng Wang, Shuai Sheng and Xudong Huang

    Citation: BMC Ophthalmology 2019 19:43

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  14. Content type: Research article

    To compare the protective effects of the histone deacetylase inhibitors (HDACis) β-hydroxybutyrate (βOHB), trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) on human lens epi...

    Authors: Xiaodi Qiu, Xianfang Rong, Jin Yang and Yi Lu

    Citation: BMC Ophthalmology 2019 19:42

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  15. Content type: Research article

    To evaluate the safety and efficacy of using a lid hygiene brush prototype to wipe the lid margins with lid hygiene shampoo in subjects with normal meibomian glands.

    Authors: Hirotaka Tanabe, Motoko Kawashima, Minako Kaido, Reiko Ishida, Tetsuya Kawakita and Kazuo Tsubota

    Citation: BMC Ophthalmology 2019 19:41

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  16. Content type: Research article

    Multifocal choroiditis (MFC) is multi-inflammatory lesions that occur in the retinal pigment epithelium (RPE) and the choriocapillaris. Optical examinations are the major diagnostic methods to diagnose the dis...

    Authors: Juanjuan Li, Yunpeng Li, Hua Li and Liwei Zhang

    Citation: BMC Ophthalmology 2019 19:39

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  17. Content type: Research article

    Globally, eye diseases are considered as one of the major contributors of nonfatal disabling conditions. In Bangladesh, 1.5% of adults are blind and 21.6% have low vision. Therefore, this paper aimed to identi...

    Authors: Ipsita Sutradhar, Priyanka Gayen, Mehedi Hasan, Rajat Das Gupta, Tapash Roy and Malabika Sarker

    Citation: BMC Ophthalmology 2019 19:38

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  18. Content type: Research article

    Pediatric ocular trauma is a major source of morbidity and blindness and the number of epidemiological studies is incommensurate with its significance. We sought to determine differences in epidemiologic patte...

    Authors: Ryan Gise, Timothy Truong, Afshin Parsikia and Joyce N. Mbekeani

    Citation: BMC Ophthalmology 2019 19:37

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  19. Content type: Research article

    To measure peripapillary retinal nerve fiber layer (RNFL) thickness and posterior pole retinal thickness in primary angle-closure suspects (PACS) by Spectral domain optical coherence tomography (SD-OCT) and to...

    Authors: Yi Zha, Wei Huang, Jinfei Zhuang and Jianqiu Cai

    Citation: BMC Ophthalmology 2019 19:36

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  20. Content type: Research article

    Dry eye disease (DED) is a prevalent complication of diabetes and presents as reduced tear production and/or increased corneal surface sensitivity often with secondary ocular surface changes. This study examin...

    Authors: Patricia J. McLaughlin, Joseph W. Sassani, Michelle B. Titunick and Ian S. Zagon

    Citation: BMC Ophthalmology 2019 19:35

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  21. Content type: Research article

    Few studies have investigated the prevalence of refractive error (RE) in older adults in China, and most have focused on East China. Our study determined the prevalence and risk factors of RE in Han and Yi adu...

    Authors: Meng Wang, Jiantao Cui, Guangliang Shan, Xia Peng, Li Pan, Zhimei Yan, Jie Zhang, Yong Zhong and Jin Ma

    Citation: BMC Ophthalmology 2019 19:33

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  22. Content type: Research article

    To evaluate the accuracy of biometric measurements by a swept-source optical coherence tomography (SS–OCT) based biometry for intraocular lens (IOL) power calculation.

    Authors: Youngju An, Eun-Kyoung Kang, Hyojin Kim, Min-Ji Kang, Yong-Soo Byun and Choun-Ki Joo

    Citation: BMC Ophthalmology 2019 19:30

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  23. Content type: Case report

    Bone wax is the most widely used hemostatic bone sealant because of its availability, ease of use, immediate action, and minimal adverse effects. Several complications have been reported to be associated with ...

    Authors: Yangbo Zhou, Minhong Li, Xin Wei, Xue Yang, Jialin Zhang and Xin Qi

    Citation: BMC Ophthalmology 2019 19:29

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  24. Content type: Research article

    A recent meta-analysis revealed PAX6 as a risk gene for myopia. There is a link between PAX6 and HOXA9. Furthermore, HOXA9 has been reported to activate TGF-β that is a risk factor for myopia. We speculate HOXA9 ...

    Authors: Chung-Ling Liang, Po-Yuan Hsu, Cheryl S. Ngo, Wei Jie Seow, Neerja Karnani, Hong Pan, Seang-Mei Saw and Suh-Hang H. Juo

    Citation: BMC Ophthalmology 2019 19:28

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  25. Content type: Technical advance

    Color fundus photography have been extensively used to explore the link between retinal morphology changes associated with various disease i.e. Diabetic Retinopathy, Glaucoma. The development of multimodal ima...

    Authors: Aqsa Ajaz, Behzad Aliahmad, Himeesh Kumar, Marc Sarossy and Dinesh K. Kumar

    Citation: BMC Ophthalmology 2019 19:27

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  26. Content type: Research article

    A few case reports have described accidental eye injuries caused by fish hooks. The severity of ocular injuries is dependent on the involved ocular structures. Severe ocular injuries due to fish hooks are rare...

    Authors: Konstantine Purtskhvanidze, Mark Saeger, Felix Treumer, Bernhard Nölle and Johann Roider

    Citation: BMC Ophthalmology 2019 19:26

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  27. Content type: Research article

    To determine the levels of connective tissue growth factor (CTGF) and hepatocyte growth factor (HGF) in the vitreous of patients with high myopia, in comparison with those with a vitreomacular interface diseas...

    Authors: Xinyi Ding, Rong Zhang, Shujie Zhang, Hong Zhuang and Gezhi Xu

    Citation: BMC Ophthalmology 2019 19:25

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  28. Content type: Research article

    The purpose of this study was to evaluate the changes in choroidal thickness and lamina cribrosa position after nonpenetrating deep sclerectomy (NPDS) and trabeculectomy.

    Authors: Aymeric Bouillot, Alexandra Pierru, Esther Blumen-Ohana, Emmanuelle Brasnu, Christophe Baudouin and Antoine Labbé

    Citation: BMC Ophthalmology 2019 19:24

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  29. Content type: Research article

    By investigating that (i) all-trans retinoic acid (ATRA) affects human retinal pigment epithelium (RPE) in expressing and secreting transforming growth factor (TGF)-β2 and (ii) U73122 (phospholipase C inhibitor) ...

    Authors: Daren Zhang, Zhihong Deng, Jia Tan, Shuirong Liu, Shuyu Hu, Hui Tao and Renhong Tang

    Citation: BMC Ophthalmology 2019 19:23

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  30. Content type: Research article

    To identity the effect of lacrimal system irrigation in the acute stage in children with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN).

    Authors: Qin Xiang, Xu Gao, Jing Fang, Lianhong Pi, Xinke Chen, Lin Chen and Qing Liu

    Citation: BMC Ophthalmology 2019 19:22

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  31. Content type: Technical advance

    The complete disassembly of nuclear is the most challenging step in hard cataract surgery through microincision. The classic phaco chop technique often does not succeed, resulting in incomplete nuclear segment...

    Authors: Ding Chen, Qunwu Tang, Fang Yu, Xueting Cai and Fan Lu

    Citation: BMC Ophthalmology 2019 19:20

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  32. Content type: Research article

    Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) an...

    Authors: Verónica Castro-Navarro, Enrique Cervera-Taulet, Catalina Navarro-Palop, Clara Monferrer-Adsuara, Laura Hernández-Bel and Javier Montero-Hernández

    Citation: BMC Ophthalmology 2019 19:15

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  33. Content type: Case report

    Thyroid-associated orbitopathy (TAO) constitutes an immune-mediated inflammation of the orbital tissues of unclear etiopathogenesis. TAO is most prevalent in hyperthyroid patients with Graves’ disease (GD); ho...

    Authors: Ewa Cyranska-Chyrek, Michal Olejarz, Ewelina Szczepanek-Parulska, Piotr Stajgis, Anna Pioch and Marek Ruchala

    Citation: BMC Ophthalmology 2019 19:9

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  34. Content type: Research article

    Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implant...

    Authors: Lixiong Gao, Lijun Zhou, Chunyu Tian, Na Li, Weiyang Shao, Xiujun Peng and Qian Shi

    Citation: BMC Ophthalmology 2019 19:8

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