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  1. To compare the changes in the anterior segment after femtosecond laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) using a dual rotating Scheimpflug (DRS) analyzer (Galile...

    Authors: Bu Ki Kim, Su Joung Mun, Young Hoon Yang, Ji Sun Kim, Jun Hyung Moon and Young Taek Chung

    Citation: BMC Ophthalmology 2019 19:251

    Content type: Research article

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  2. Retinal pigment epithelium cells (RPEs) are critical for maintaining retinal homeostasis. Accumulation of age-related lipofuscin, N-retinylidene-N-retinylethanolamine (A2E), makes RPEs vulnerable to blue light...

    Authors: Jingyang Feng, Yuhong Chen, Bing Lu, Xiangjun Sun, Hong Zhu and Xiaodong Sun

    Citation: BMC Ophthalmology 2019 19:249

    Content type: Research article

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  3. The study was proposed to determine whether nerve growth factor (NGF) combined with an internal limiting membrane (ILM) insertion was effective in the large idiopathic full-thickness macular hole (iFTMH) therapy.

    Authors: Luyi Zhang, Xiaoxia Li, Xiaoli Yang, Yu Shen and Miaoqin Wu

    Citation: BMC Ophthalmology 2019 19:247

    Content type: Research article

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  4. Alström syndrome (AS) is a rare monogenic disorder characterized by progressive multi-organ pathology including retinal degeneration, hearing impairment and type 2 diabetes. Here we present clinical features i...

    Authors: Maria F. Shurygina, Maria A. Parker, Catie L. Schlechter, Rui Chen, Yumei Li, Richard G. Weleber, Paul Yang and Mark E. Pennesi

    Citation: BMC Ophthalmology 2019 19:246

    Content type: Case report

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  5. We aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia.

    Authors: Shuyi Yuan, Shuxian Zhang, Yanglin Jiang and Lihua Li

    Citation: BMC Ophthalmology 2019 19:242

    Content type: Research article

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  6. RP (retinitis pigmentosa) is a group of hereditary retinal degenerative diseases. XLRP is a relatively severe subtype of RP. Thus, it is necessary to identify genes and mutations in patients who present with X...

    Authors: Zhimeng Zhang, Hehua Dai, Lei Wang, Tianchang Tao, Jing Xu, Xiaowei Sun, Liping Yang and Genlin Li

    Citation: BMC Ophthalmology 2019 19:240

    Content type: Research article

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  7. So far only single cases with short follow-up have been reported on the use of intravitreal anti-VEGF for traumatic choroidal neovascularizations (CNV). This paper reports a large case series of patients with ...

    Authors: T. Barth, F. Zeman, H. Helbig and M.-A. Gamulescu

    Citation: BMC Ophthalmology 2019 19:239

    Content type: Research article

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  8. Repeated surgery excisions could induce obvious irregular astigmatism in patients with recurrent pterygium. Our study is aimed to illustrate the effect of adjunct excimer laser phototherapeutic keratectomy (PT...

    Authors: Di Chen, Xiaowei Liu, Qin Long, Zhonghai Wang and Ying Li

    Citation: BMC Ophthalmology 2019 19:238

    Content type: Research article

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  9. To evaluate 5-year outcomes of anti-vascular endothelial growth factor (VEGF) monotherapy and combination therapy of anti-VEGF agents and photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV) ...

    Authors: Jingyuan Yang, Mingzhen Yuan, Erqian Wang, Song Xia and Youxin Chen

    Citation: BMC Ophthalmology 2019 19:237

    Content type: Research article

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  10. Anterior high-resolution optical coherence tomography (HR-OCT) is a novel non-invasive in vivo imaging modality that can assist in the diagnosis and management of various ophthalmic pathologies. The implementa...

    Authors: Yi-Syun Shen, Joseph L. Hu and Chao-Chien Hu

    Citation: BMC Ophthalmology 2019 19:235

    Content type: Case report

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  11. To report a modified surgical technique for intrascleral intraocular lens (IOL) fixation with fewer anterior segment manipulations in eyes lacking sufficient capsular support.

    Authors: Yuan Yang, Teng-teng Yao, Ya-li Zhou, Yi-xiao Wang and Zhao-yang Wang

    Citation: BMC Ophthalmology 2019 19:234

    Content type: Research article

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  12. Hypocalcemia is a derangement in serum calcium level due to a vast spectrum of disorders, but the most common cause is surgery, usually thyroid gland surgery. Symptoms of hypocalcemia can be due to increased n...

    Authors: Kumale Tolesa Daba, Dagmawit Kifle Weldemichael and Gersam Abera Mulugeta

    Citation: BMC Ophthalmology 2019 19:233

    Content type: Case report

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  13. Conventional flash fundus cameras capture color images that are oversaturated in the red channel and washed out in the green and blue channels, resulting in a retinal picture that often looks flat and reddish....

    Authors: Valentina Sarao, Daniele Veritti, Enrico Borrelli, Srini Vas R. Sadda, Enea Poletti and Paolo Lanzetta

    Citation: BMC Ophthalmology 2019 19:231

    Content type: Research article

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  14. To evaluate the efficacy of micro-incision vitrectomy surgery (MIVS) using Lumera and Resight non-contact sutureless wide-angle viewing systems (WAVS) for primary rhegmatogenous retinal detachment (RRD), and t...

    Authors: Chun-Ting Lai, Wei-Hsun Kung, Chun-Ju Lin, Huan-Sheng Chen, Henry Bair, Jane-Ming Lin, Wen-Lu Chen, Peng-Tai Tien and Yi-Yu Tsai

    Citation: BMC Ophthalmology 2019 19:230

    Content type: Research article

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  15. Erythropoietin (EPO) is one of the systemic angiogenic factors, and its role in ocular angiogenesis and in diabetic retinopathy (DR) is not yet fully understood. The latest research data reveal a possible corr...

    Authors: Sofija Davidović, Nikola Babić, Sandra Jovanović, Sava Barišić, Desanka Grković and Aleksandar Miljković

    Citation: BMC Ophthalmology 2019 19:227

    Content type: Research article

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  16. Fungal Keratitis (FK) is an infective keratopathy with extremely high blindness rate. The damaging effect of this disease is not only the destruction of corneal tissue during fungal infection, but also the cor...

    Authors: Yue Zhou, Yuqing Chen, Suiyue Wang, Fangyuan Qin and Liya Wang

    Citation: BMC Ophthalmology 2019 19:226

    Content type: Research article

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  17. Measurement of intraocular pressure (IOP) is essential for glaucoma patients. Many factors such as central corneal thickness (CCT) can affect the accuracy of IOP measurement. The purpose of this study was to e...

    Authors: Min Chen, Lina Zhang, Jia Xu, Xinyi Chen, Yuxiang Gu, Yuping Ren and Kaijun Wang

    Citation: BMC Ophthalmology 2019 19:225

    Content type: Research article

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  18. Corneal transplantations are surgeries performed for irreparable corneal diseases and damage. However, there is a gap between the number of potential recipients and the number of donor corneas available. The m...

    Authors: Seth Lartey, Ellen K. Antwi-Adjei, Solomon Agyapong, Abdul-Kabir Mohammed, Derrick N. O. Mensah and Edward S. Genego

    Citation: BMC Ophthalmology 2019 19:224

    Content type: Research article

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  19. To determine the accuracy of the T2 formula as applied to highly myopic eyes, to compare the T2 formula to the SRK/T and Holladay 1 formulas, and to describe possible ways to improve the estimation of corneal ...

    Authors: Carlos Alberto Idrobo-Robalino, Gisella Santaella and Ángela María Gutiérrez

    Citation: BMC Ophthalmology 2019 19:222

    Content type: Research article

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  20. Children with a brain tumor have a high risk of impaired vision. Up to now, visual acuity measurement, visual field testing and orthoptic testing are the most informative diagnostic investigations for the asse...

    Authors: M. A. Nuijts, M. H. Degeling, I. Stegeman, A. Y. N. Schouten-van Meeteren and S. M. Imhof

    Citation: BMC Ophthalmology 2019 19:220

    Content type: Study protocol

    Published on:

  21. The signaling pathway of epithelial to mesenchymal transition (EMT) is regulated by c-Src kinase in many cells. The purpose of this study was to investigate the effects of c-Src kinase on EMT of human lens epi...

    Authors: Xingyu Li, Fang Wang, Meixia Ren, Minjuan Du and Jian Zhou

    Citation: BMC Ophthalmology 2019 19:219

    Content type: Research article

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  22. Oculosporidiosis (ocular rhinosporidiosis) accounts for 15% of cases of rhinosporidiosis, which is a chronic granulomatous disease and is endemic in India and Sri Lanka. In Brazil, the climatic and hydrographi...

    Authors: Francílio Araújo Almeida, Antonio Augusto Lima Teixeira-Junior, Jaqueline Diniz Pinho, Elaine Fiod Costa and Gyl Eanes Barros Silva

    Citation: BMC Ophthalmology 2019 19:218

    Content type: Research article

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  23. To investigate the cytotoxicities of the topical ocular dual-action anti-allergic agents (alcaftadine 0.25%, bepotastine besilate 1.5%, and olopatadine HCL 0.1%) on human corneal epithelial cells (HCECs) and t...

    Authors: Sung Il Kim, Choul Yong Park, Gladys Fordjuor, Jong Heon Lee, Jong Soo Lee and Ji Eun Lee

    Citation: BMC Ophthalmology 2019 19:217

    Content type: Research article

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  24. Traumatic optic neuropathy (TON) is a form of optic nerve injury that occurs secondary to trauma and is etiologically associated with acute axonal loss with severe vision loss. Here, we reported longitudinal c...

    Authors: Won June Lee, Eun Hee Hong, Hae Min Park and Han Woong Lim

    Citation: BMC Ophthalmology 2019 19:216

    Content type: Case report

    Published on:

  25. To evaluate choroidal vascularity index (CVI) in eyes with internal carotid artery (ICA) stenosis using binarization tool in enhanced depth images scanned by spectral domain optical coherence tomography.

    Authors: Shuang Li, Xuqiang Lang, Wei Wang, Yang Yang, Jingjing Wang, Hongyang Li, Yanling Wang and Kang Wang

    Citation: BMC Ophthalmology 2019 19:215

    Content type: Research article

    Published on:

  26. The common presence of human leukocyte antigen (HLA)-DRB1*04 in Vogt-Koyanagi-Harada (VKH) disease is well known. The aim of this study was to investigate the relationship between visual prognosis and HLA-DRB1...

    Authors: Norihiko Misawa, Mizuki Tagami, Takeya Kohno and Shigeru Honda

    Citation: BMC Ophthalmology 2019 19:214

    Content type: Research article

    Published on:

  27. This study aims to optimize the therapeutic regimen for refractory obstructive meibomian gland dysfunction (o-MGD) patients by combining intraductal meibomian gland probing (MGP) and intense pulsed light (IPL)...

    Authors: Xiaodan Huang, Qiyu Qin, Linping Wang, Jiao Zheng, Lin Lin and Xiuming Jin

    Citation: BMC Ophthalmology 2019 19:211

    Content type: Research article

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  28. Uveal effusion syndrome is a rare entity of idiopathic exudative detachments of uveal tissues and retina. Medical treatments with systemic steroids and antimetabolites have been tried but with variable results...

    Authors: Anadi Khatri, Sweta Singh, Kriti Joshi and Muna Kharel

    Citation: BMC Ophthalmology 2019 19:210

    Content type: Case report

    Published on:

  29. Crouzon syndrome (CS), which results from fibroblast growth factor receptor 2 mutations, is associated with craniosynostosis, exophthalmos, and other symptoms. Herein, we report the genetic abnormalities detec...

    Authors: Ji Yang, Tao Tao, Hai Liu and Zhu-Lin Hu

    Citation: BMC Ophthalmology 2019 19:209

    Content type: Case report

    Published on:

  30. Opacification of hydrophobic and hydrophilic intraocular lenses (IOLs) has been reported. Herein, we report a case of spontaneous resolution of opacification following acute clouding of a trifocal IOL, which c...

    Authors: Tao Zhang, Shaowei Li, Chang Liu, Ruihua Zhao, Chenghe Chang and Na Han

    Citation: BMC Ophthalmology 2019 19:208

    Content type: Case report

    Published on:

  31. Real-world data (RWD) has been a valuable addition to the scientific literature regarding treatment pathways, clinical outcomes and characteristics of patients with retinal diseases in recent years. Registries...

    Authors: Vincent Daien, Bora M. Eldem, James S. Talks, Jean-Francois Korobelnik, Paul Mitchell, Robert P. Finger, Taiji Sakamoto, Tien Yin Wong, Obaro Evuarherhe, Gemma Carter and Joao Carrasco

    Citation: BMC Ophthalmology 2019 19:206

    Content type: Research article

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  32. To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols.

    Authors: Isabel Rodríguez-Pérez, Juan Gros-Otero, Miguel A. Teus, Rafael Cañones and Montserrat García-González

    Citation: BMC Ophthalmology 2019 19:205

    Content type: Research article

    Published on:

  33. The metabolic activity of retina is higher than other human tissues and is crucial to the vision. Cynomolgus macaques is widely used in ophthalmic disease research. The evaluation and comparison of macular and...

    Authors: Jingyi Peng, Liuxueying Zhong, Li Ma, Jiayi Jin, Yongxin Zheng and Chenjin Jin

    Citation: BMC Ophthalmology 2019 19:204

    Content type: Research article

    Published on:

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