Characteristic | Site No.7 | Other sites | p-value |
---|---|---|---|
Baseline best-corrected VA (logMAR) | |||
Mean (SD) | 0.61 (0.26) | 0.62 (0.24) | 0.8429 |
Time from NV-AMD diagnosis to baseline (months) | |||
N | 18 | 55 | |
Mean (SD) | 0.33 (0.77) | 3.13 (6.65) | 0.0808 |
Median (range) | 0.0 (0--3) | 0.0 (0--31) | |
Angiographic subtype, n (%) | 0.1937 | ||
Minimally classic | 0 (0.0) | 4 (7.3) | |
Occult | 12 (66.7) | 43 (78.2) | |
Predominantly classic | 5 (27.8) | 6 (10.9) | |
Missing | 1 (5.6) | 2 (3.6) | |
Lesion size (disc area), n (%) | 0.1376 | ||
<2 | 9 (50.0) | 17 (30.9) | |
≥ 2 and < 4 | 7 (38.9) | 15 (27.3) | |
≥ 4 | 1 (5.6) | 10 (18.2) | |
Missing | 1 (5.6) | 13 (23.6) | |
Geographic atrophy, n (%) | 0.0545 | ||
Present | 0 (0.0) | 10 (18.2) | |
Absent | 17 (94.4) | 37 (67.3) | |
Missing | 1 (5.6) | 8 (14.5) | |
Presence of blood, n (%) | 0.4277 | ||
Present | 4 (22.2) | 21 (38.2) | |
Absent | 13 (72.2) | 30 (54.5) | |
Missing | 1 (5.6) | 4 (7.3) | |
Met early disease definition No.1* | 5 (29.4) | 13 (31.0) | 1.0000 |
Met early disease definition No.2† | 5 (29.4) | 30 (61.2) | 0.0281 |
VA, baseline to month 6 (logMAR) Mean (SD) | -0.04 (0.22) | 0.11 (0.36) | 0.0970 |
VA change, baseline to month 6 | |||
Gained ≥ 0 lines | 15 (83.3) | 27 (49.1) | 0.0134 |
Gained ≥ 3 lines | 3 (16.7) | 9 (16.4) | 1.0000 |
Lost < 3 lines | 1 (5.6) | 8 (14.5) | 0.4365 |
Lost ≥ 6 lines | 0 (0.0) | 8 (14.5) | 0.1871 |