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Table 2 Intraocular pressure (IOP) at baseline and month 3 (mmHg), ITT population

From: First-line latanoprost therapy in ocular hypertension or open-angle glaucoma patients: a 3-month efficacy analysis stratified by initial intraocular pressure

 

Baseline IOP

 

20 to <24 mmHg

N = 252

≥ 24 mmHg

N = 320

Baseline IOP, mmHg

  

   Mean ± SD

22.2 ± 0.9

26.7 ± 2.8

Month 3 IOP, mmHg

  

   Mean ± SD

16.0 ± 2.3

17.5 ± 3.2

IOP change from baseline to month 3, mmHg

  

   Mean ± SD

-6.3 ± 2.4

-9.2 ± 3.7

   p-value*

<0.0001

<0.0001

% change in IOP from baseline to month 3

  

   Mean ± SD

-28.0 ± 10.6

-34.1 ± 11.9

≥ 10% IOP reduction from baseline to month 3

  

   n (%)

237 (94.1)

310 (96.9)

≥ 30% IOP reduction from baseline to month 3

  

   n (%)

122 (48.4)

210 (65.6)

  1. *p-value based on t test for paired data.
  2. p = 0.10 for between-group difference; chi-square test.
  3. p < 0.0001 for between-group difference; chi-square test.
  4. ITT = intent to treat; SD = standard deviation.