Comparative efficacy and safety of the fixed versus unfixed combination of latanoprost and timolol in Chinese patients with open-angle glaucoma or ocular hypertension

Table 2 Change in diurnal IOP pressure (mmHg) at week 8 (primary endpoint)*

	LTFC N = 125	LTuFC N = 123
Baseline, mean ± SD	25.8 ± 3.2	26.0 ± 3.5
Week 8, mean ± SD	17.5 ± 2.9	17.2 ± 3.0
Change from baseline to week 8, mean ± SD	-8.3 ± 3.2	-8.8 ± 3.8
(95% CI)	(-8.9 to -7.7)	(-9.5 to -8.1)
LS mean change	-8.6	-8.9
Difference in LS means (95% CI)	0.3 (-0.3 to 1.0)

*Intent-to-treat population.
CI = confidence interval; LTFC = latanoprost/timolol fixed combination; IOP = intraocular pressure; LS = least square; SD = standard deviation; LTuFC = latanoprost/timolol unfixed combination.

ISSN: 1471-2415