Figure 2
From: Brimonidine protects against loss of Thy-1 promoter activation following optic nerve crush
Inverted fluorescent retinal neurons imaged in vivo using bCSLO at baseline (A and C) and in the same eyes at 4 weeks (B and D) after optic nerve crush from a mouse that received saline treatment (A, B) and a mouse that received repeated brimonidine treatment (C,D). Fluorescent neurons appear as black spots, axon bundles appear as dark thin lines radiating from the optic nerve head (seen more easily in B and D), while retinal blood vessels appear as bright thick lines branching from the optic nerve head.