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Table 3 Comparison of the clinical characteristics between Group 1A (cases in which transparency was maintained after recovery from rejection, n = 25) and Group 1B (cases in which the decompensation occurring after transparency recovered, n = 12)

From: Prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty

 

Group 1A

Group 1B

OR

P-Value

 

mean ± SD

mean ± SD

(95% CI)

 
 

n (%)

n (%)

  

Age (years)

58.4 ± 17.4

61.5 ± 10.8

0.99 (0.94–1.03)

0.57

Sex

 Male

17 (68.0)

6 (50.0)

2.13 (0.52–8.70)

0.29

 Female

8 (32.0)

6 (50.0)

  

Diagnosis before previous PKP

 Bullous keratopathy

8 (32.0)

5 (41.7)

0.66 (0.16–2.73)

0.57

 Regraft

2 (8.0)

6 (50.0)

0.09 (0.01–0.54)

0.0091

 Corneal scarring

8 (32.0)

1 (8.3)

5.18 (0.57–47.32)

0.14

 Corneal dystrophy

3 (12.0)

0 (0.0)

1.00

 Keratoconus

3 (12.0)

0 (0.0)

1.00

 Corneal ulcer

1 (4.0)

0 (0.0)

1.00

Type of surgery

 PKP

17 ((68.0)

10 (83.3)

0.43 (0.08–2.41)

0.33

 PKP + ECCE + IOL

7 (28.0)

2 (16.7)

1.94 (0.34–11.20)

0.46

 PKP + IOL suture

1 (4.0)

0 (0.0)

1.00

history of glaucoma

5 (20.0)

3 (25.0)

0.75 (0.15-3.84)

0.73

Previous episodes of rejection

1 (4.0)

4 (33.3)

0.13 (0.01–1.36)

0.09

ECD before rejection

1523 ± 666

2010 ± 876

0.999 (0.998–1.001)

0.19

Interval between PKP and rejection (months)

41.3 ± 44.2

16.8 ± 23.3

1.03 (0.99–1.06)

0.12

Interval between rejection and treatment with systemic steroids (days)

6.5 ± 5.5

5.8 ± 6.1

1.02 (0.89–1.15)

0.80

Systemic steroid

 Dexamethasone phosphate

20 (80.0)

9 (75.0)

1.33 (0.26–6.83)

0.73

 Methylprednisolone

5 (20.0)

3 (25.0)

0.75 (0.15–3.84)

0.73

Interval between treatment and recovery of transparency (days)

72.5 ± 70.4

93.0 ± 208.0

0.999 (0.994–1.004)

0.65

  1. ECCE, extracapsular cataract extraction; ECD, endothelial cell density; IOL, intraocular lens; PKP, penetrating keratoplasty; SD, standard deviation.