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Table 2 The parameters of cosinor analysis for different groups of subjects

From: Longitudinal stability of the diurnal rhythm of intraocular pressure in subjects with healthy eyes, ocular hypertension and pigment dispersion syndrome

Subjects n MESOR [mmHg] Amplitude [mmHg] Acrophase [h:min] Circ. SD [h:min]
All 52 16.0 ± 2.3 1.9 ± 0.6 10:37 4:52
Normal 30 15.4 ± 1.5 1.7 ± 0.4 10:32 5:15
OHT 11 19.0 ± 2.0b,c 2.6 ± 0.7b,c 09:42 4:06
PDS 11 14.9 ± 1.8 2.0 ± 0.6 11:48 4:21
Younga 26 16.2 ± 2.1 1.9 ± 0.5 10:56 4:30
Olda 26 15.9 ± 2.4 1.9 ± 0.7 10:14 5:12
Hospital 13 15.7 ± 1.8 2.1 ± 0.6 10:51 3:42
Ambulatory 16 16.6 ± 2.5 2.0 ± 0.7 10:22 4:53
Mixed 23 15.8 ± 2.3 1.7 ± 0.6 10:36 5:34
  1. MESOR: Midline Estimating Statistic Of Rhythm, i.e. mean IOP level of the cosine curve; acrophase: time of peak of cosine curve; circ. SD: circular standard deviation.
  2. a)Young: ≤ median age of 44.4 years; old: > 44.4 years.
  3. b)Tukey HSD test significant vs. normal (only performed if ANOVA was significant).
  4. c)Tukey HSD test significant vs. PDS.