Figure 2

Horizontal enhanced depth imaging optical coherence tomography (EDI-OCT) images across the fovea of the right eye. Right panels are magnified views of the area indicated in the left panels. A, At the initial visit, ganglion cell layer (GCL) hyper-reflectivity (black arrowheads), photoreceptor inner segment/outer segment junction boundary loss, detachment between the retinal pigment epithelium (RPE) and Bruch’s membrane, moderately reflective, dome-shaped focal lesions (white arrowheads) in the photoreceptor layer were present and corresponded to the large white dot at the temporal fovea. The site with pigment epithelium detachment involved the RPE/Bruch’s membrane ruptures (red and yellow arrowheads). Choroidal thickness at the fovea and the adjacent temporal lesion was 243 and 330 μm, respectively. B, One month later, the pigment epithelium detachment and abnormal GCL hyper-reflectivity spontaneously resolved. Focal lesions in the photoreceptor layer also markedly decreased. However, this region developed a conforming-type focal choroidal excavation (FCE) and the choroidal thickness at the fovea and the FCE lesion decreased to 210 and 140 μm, respectively. An abnormal hyper-reflective lesion also appeared within the choroid beneath the FCE (arrow). C, Three months after the initial visit, focal lesions in the photoreceptor layer almost resolved, but cystoid changes in the inner retinal layers and marked outer layer thinning occurred. The abnormal hyper-reflective lesion (yellow arrows) in the region of the scar within the choroid increased in size compared to that at 1 month (Figure 2B, arrow). The subfoveal choroidal thickness further decreased to 181 μm.