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Table 3 The association test for the genotype of rs6982567

From: Association of rs6982567 near GDF6with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort

  

Genotype distribution

Genotype

Group

Genotype

Case

Control

OR (95%CI) p value

Model

OR (95%CI) p value

PCV

CC

117

106

reference

Additive

1.31(0.97-1.78) 0.0747

 

TC

110

89

1.12(0.76-1.64) 0.5657

Dominant

1.24(0.86-1.79) 0.2560

 

TT

24

9

2.42(1.07-5.43) 0.0290

Recessive

2.29(1.04-5.05) 0.0351

nAMD

CC

92

106

reference

Additive

0.91(0.65-1.29) 0.5961

 

TC

53

89

0.69(0.44-1.07) 0.0931

Dominant

0.76(0.50-1.16) 0.2088

 

TT

12

9

1.54(0.62-3.81) 0.3510

Recessive

1.79(0.74-4.37) 0.1936

PCV + nAMD

CC

209

106

reference

Additive

1.14(0.87-1.50)0.3390

 

TC

163

89

0.93(0.66-1.32) 0.6801

Dominant

1.03(0.74-1.44) 0.8625

 

TT

36

9

2.03(0.94-4.37) 0.0660

Recessive

2.10(0.99-4.44) 0.0487

  1. SNP: single nucleotide polymorphism.
  2. PCV: polypoidal choroidal vasculopathy.
  3. nAMD: neovascular age-related macular degeneration.
  4. OR: odds ratio; 95% CI: 95% confidence interval.
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BMC Ophthalmology

ISSN: 1471-2415

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