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Table 3 Analyses of the MTHFR C677T genotype and RVO

From: Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism, and risk of retinal vein occlusion: an updated meta-analysis

Compared genotype

No. of studies

OR (95% CI)

P

Heterogeneity

P Egger’s testa

P Begg’s testb

    

x2

I2

P

  

TT VS. CC/CT

23

1.16 (0.89–1.50)

0.268

36.66

40.0%

0.026

0.551

1.000

CC VS. TT/CT

14

0.77 (0.57,1.05)

0.098

37.78

65.6%

<0.001

0.510

0.584

TT VS. CC

14

1.30 (0.85,1.98)

0.223

28.78

54.8%

0.007

0.056

0.063

CT VS. CC

14

1.22 (0.90,1.66)

0.202

34.8

62.6%

0.001

0.109

0.101

  1. a P Egger’s test = the P value for Egger’s test.
  2. b P Begg’s test = the P value for Begg’s test.
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BMC Ophthalmology

ISSN: 1471-2415

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