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Table 2 Seropositivity associated with different stages of AMD and control group

From: Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration

AMD stage

Total seropositivity

Patients seropositive for a single antigen

Unique antigens*

Controls

14/26 (54%)

5/26 (19%)

35 k (12%)

68 k (16%)

46 k (28%)

Intermediate AMD

26/41 (63%)

21/41 (51%)

40 k (10%)

42 k (16%)

46 k (41%)

Late AMD - Geographic Atrophy

18/28 (64%)

9/28 (32%)

30 k (23%)

46 k (46%)

Late AMD - Neovascular AMD

16/33 (49%)

10/33 (30%)

32 k (13%)

35 k (21%)

46 k (29%)

60 k (8%)

Late AMD - Both GA + NV

4/6 (67%)

4/6 (67%)

Not determined

  1. *Unique retinal antigens are presented as a percentage of total recognized antigens present within a group.Antigens are identified by molecular weight (K = 1000).