From: Low vision due to cerebral visual impairment: differentiating between acquired and genetic causes
General information | Median (range) |
---|---|
Age first examination (months) | 36 (4 months- 45 years) |
Age most recent examination (months) | 53 (5 months – 45 years) |
Birth weight (gram) | 2980 (760–4750) |
Gestational age (weeks) | 39 (27–42) |
Regarding N/ Available N (%) | |
Men | 170/309 (55%) |
Mortality | 15/309 (5%) |
Twins | 20/309 (6%) |
Gestational age <37 weeks | 71/222 (32%) |
Vigabatrin use | 44/309 (14%) |
Anomalies MRI-cerebrum | 178/206 (86%) |
Co-morbidities | Affected N/ Available N (%) |
Intellectual disability | 298/309 (96%) |
Motor impairment | 288/294 (98%) |
Hearing impairment | 24/196 (12%) |
Etiology | Number (%) |
Perinatal problems* | 70 (23%) |
PVL* | 35 |
Stroke* | 32 |
Exogenic* | 33 (11%) |
Meningitis/encephalitis * | 13 |
Congenital CMV infection* | 6 |
Headtrauma* | 6 |
Complication of operation/co-morbidity* | 8 |
Genetic diagnosis* | 66 (21%) |
Hydrocephalus* | 20 (6%) |
West syndrome* | 28 (9%) |
Unknown | 125 (40%) |