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Table 5 Genotype and allele distributions in PCV patients and control group

From: Associations of complement factor B and complement component 2 genotypes with subtypes of polypoidal choroidal vasculopathy

    Total PCV patients Polypoidal CNV Typical PCV Control
    Number % p-value Number % p-value Number % p-value Number %
rs547154 Genotype G/G 255 90.4% 80 95% 175 88% 229 84%    
   T/G 26 9.2% 0.0400 4 5% 0.023 22 11% 0.276 41 15%
   T/T 1 0.4%   0 0%   1 1%   4 1%
  Dominant model G/G 255 90.4% 0.016 80 95% 0.007* 175 88% 0.142 229 84%
   TG + TT 27 9.6%   4 5%   23 12%   45 16%
  Recessive model TT 1 0.4% 0.168 0 0% 0.265 1 1% 0.317 4 1%
   TG + GG 281 99.6%   84 100%   197 99%   270 99%
  Allele G 536 95.0% 0.009* 164 98% 0.004* 372 94% 0.110 499 91%
   T 28 5.0%   4 2%   24 6%   49 9%
rs541862 Genotype T/T 255 90.4%   80 95%   175 88%   229 84%
   T/C 26 9.2% 0.049 4 5% 0.023 22 11% 0.318 42 15%
   C/C 1 0.4%   0 0%   1 1%   3 1%
  Dominant model T/T 255 90.4% 0.016 80 95% 0.007* 175 88% 0.142 229 84%
   TC + CC 27 9.6%   4 5%   23 12%   45 16%
  Recessive model C/C 1 0.4% 0.302 0 0% 0.336 1 1% 0.490 3 1%
   TC + TT 281 99.6%   84 100%   197 99%   271 99%
  Allele T 536 95.0% 0.013 164 98% 0.004* 372 94% 0.137 500 91%
   C 28 5.0%   4 2%   24 6%   48 9%
rs2072633 Genotype G/G 50 17.7%   13 15%   37 19%   69 25%
   G/A 131 46.5% 0.017 34 40% 0.005* 97 49% 0.149 134 49%
   A/A 101 35.8%   37 44%   64 32%   71 26%
  Dominant model G/G 50 17.7% 0.032 13 15% 0.064 37 19% 0.095 69 25%
   GA + AA 232 82.3%   71 85%   161 81%   205 75%
  Recessive model A/A 101 35.8% 0.012* 37 44% 0.002* 64 32% 0.128 71 26%
   GA + GG 181 64.2%   47 56%   134 68%   203 74%
  Allele G 231 41.0% 0.004* 60 36% 0.002* 171 43% 0.055 272 50%
   A 333 59.0%   108 64%   225 57%   276 50%
rs4151667 Genotype T/T 273 96.8%   81 96%   192 97%   261 95%
   A/T 9 3.2% 0.348 3 4% 0.649 6 3% 0.350 13 5%
   A/A 0 0.0%   0 0%   0 0%   0 0%
  Dominant model T/T 273 96.8% 0.348 81 96% 0.649 192 97% 0.350 261 95%
   AT + AA 9 3.2%   3 4%   6 3%   13 5%
  Recessive model A/A 0 0.0% - 0 0% - 0 0% - 0 0%
   AT + TT 282 100.0%   84 100%   198 100%   274 100%
  Allele T 555 98.4% 0.394 165 98% 0.775 390 98% 0.482 535 98%
   A 9 1.6%   3 2%   6 2%   13 2%
  1. PCV; polypoidal choroidal vasculopathy CNV; choroidal neovascularization.
  2. p- values are for the comparison between cases and controls.
  3. p- values for genotypes were calculated by Fisher’s exact test. (after Bonferroni correction *p < 0.0125).