Relationship between visual field loss and contrast threshold elevation in glaucoma

BMC Ophthalmology

Table 1 Clinical data for glaucoma and OHT patients

Pat no.	Age (yr)	LE Condition	LE VA	LE VF loss	LE CT_max	RE Condition	RE VA	RE VF loss	RE CT_max	I-O diff	R²
1	72	POAG	6/5	74%	0.051	POAG	6/4	7%	0.023	0.025	79%*
2	73	POAG	6/6	60%	0.098	POAG	6/7.5	51%	0.168	0.045	0%°
3	67	POAG	6/6	4%	0.099	NPG	6/9	53%	0.107	0.004	48%⁺
4	76	POAG	6/6	7%	0.075	POAG	6/7.5	44%	0.078	0.001	1%°
5	71	POAG	6/6	36%	0.142	POAG	6/6	30%	0.067	0.045	0%°
6	66	POAG	6/6	17%	0.075	POAG	6/12	7%	0.091	0.014	-25%°
7	77	POAG	6/24	55%	0.055	POAG	6/6	67%	0.044	0.012	14%°
8	68	POAG	6/6	23%	0.069	normal	6/5	4%	0.049	0.019	55%*
9	75	POAG	6/9	44%	0.102	normal	6/5	1%	0.041	0.034	85%*
10	72	normal	6/6	2%	0.023	POAG	6/9	42%	0.031	0.006	47%⁺
11	37	POAG	6/18	14%	0.089	blind	nil	100%	n/s	na	na
12	83	POAG pxf	6/9	1%	0.066	POAG pxf	6/9	51%	n/s	na	na
13	83	POAG pxf	6/18	69%	0.058	POAG pxf	6/12	46%	0.074	0.025	-24%°
14	74	POAG pxf	6/5	26%	0.067	OHT	6/6	3%	0.056	0.008	9%°
15	73	NPG	6/5	17%	0.055	NPG	6/5	47%	0.033	0.014	0%°
16	76	NPG	6/9	18%	0.150	NPG	6/12	47%	0.060	0.021	46%⁺
17	73	NPG	6/9	53%	0.048	normal	6/9	4%	0.027	0.010	49%⁺
18	54	RD	6/12	2%	0.046	NPG	6/5	41%	0.083	0.023	85%*
19	61	PCACG	6/9	11%	0.078	ACG	6/9	3%	0.072	0.012	na
20	79	PTG	6/9	55%	0.147	normal	6/9	6%	0.077	0.055	26%°
21	55	normal	6/6	7%	0.044	SIG	6/6	52%	0.058	0.017	73%*
22	70	OHT	6/5	0%(2%)	0.031	OHT	6/5	0% (6%)	0.018	0.002	na
23	78	OHT	6/5	0% (7%)	0.022	OHT	6/9	3% (8%)	0.033	0.0064	na
24	57	OHT	6/5	6% (13%)	0.054	OHT	6/5	4%(13%)	0.051	0.0006	na
25	62	OHT	6/5	2% (2%)	0.034	OHT pdc	6/12	4% (6%)	0.042	0.010	na
26	72	A OHT pdc	6/60	8% (29%)	0.155	OHT pdc	6/12	8% (35%)	0.059	0.068	na

Pat no. Patient number, LE left eye, RE right eye, A amblyopic, CT_maxhighest contrast threshold value (to be compared against the upper prediction limit of 0.045), I-O diff inter-ocular difference (to be compared against the upper prediction limit of 0.006), NPG normal pressure glaucoma, OHT ocular hypertensive, na not applicable, n/s not seen, PCACG primary chronic angle closure glaucoma, pdc pathological cupping of optic disc, POAG primary open angle glaucoma, PTG post-traumatic glaucoma, pxf pseudoexfoliation, RD retinal detachment, SIG sarcoid-induced glaucoma, VA visual acuity, VF visual field. Negative R ² values denote inverse relationship. *p < 0.05, ⁺0.05 <p < 0.10, °p > 0.10. Some eyes denoted normal show visual field loss due to the blind spot while some glaucomatous eyes showing minimal visual loss had additional loss either more peripheral or more central to the truncated quadrant. OHT patients also show visual field loss score in parenthesis at 12 months follow-up examinations.

ISSN: 1471-2415