Skip to main content

Table 1 Influence of bimatoprost on retrobulbar hemodynamics. Influence of bimatoprost on ocular perfusion. Overview of the results from CDI measurements before and one month after regular application of bimatoprost: Increase of blood flow velocities were statistically not significant (n = 11). Bold printed measures were subjected to statistical testing; all other parameters were observational only.

From: Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428]

  

PSV (cms-1)

EDV (cms-1)

RI

PI

OA

before bimatoprost

31.6 ± 3.5

3.5 ± 0.9

0.89 ± 0.02

2.76 ± 0.20

 

after bimatoprost

38.5 ± 4.8

4.2 ± 0.7

0.87 ± 0.03

2.53 ± 0.21

CRA

before bimatoprost

7.9 ± 0.9

1.4 ± 0.2

0.79 ± 0.04

2.22 ± 0.31

 

after bimatoprost

8.1 ± 0.5

1.7 ± 0.1

0.79 ± 0.02

1.90 ± 0.10

SPCA

before bimatoprost

8.0 ± 1.1

1.9 ± 0.1

0.71 ± 0.03

1.61 ± 0.15

 

after bimatoprost

10.1 ± 1.2

2.8 ± 0.4

0.75 ± 0.01

1.66 ± 0.05

LPCA

before bimatoprost

14.8 ± 3.0

3.0 ± 0.7

0.78 ± 0.03

1.90 ± 0.17

 

after bimatoprost

16.8 ± 2.2

3.0 ± 0.3

0.80 ± 0.02

1.90 ± 0.12

  1. Abbreviations: OA – Ophthalmic artery, CRA – central retinal artery, SPCA – short posterior ciliary artery, LPCA – long posterior ciliary artery, PSV – peak systolic velocity, EDV – enddiastolic velocity, RI – resistive index, PI – pulsatility index.