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Table 1 Influence of bimatoprost on retrobulbar hemodynamics. Influence of bimatoprost on ocular perfusion. Overview of the results from CDI measurements before and one month after regular application of bimatoprost: Increase of blood flow velocities were statistically not significant (n = 11). Bold printed measures were subjected to statistical testing; all other parameters were observational only.

From: Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428]

   PSV (cms-1) EDV (cms-1) RI PI
OA before bimatoprost 31.6 ± 3.5 3.5 ± 0.9 0.89 ± 0.02 2.76 ± 0.20
  after bimatoprost 38.5 ± 4.8 4.2 ± 0.7 0.87 ± 0.03 2.53 ± 0.21
CRA before bimatoprost 7.9 ± 0.9 1.4 ± 0.2 0.79 ± 0.04 2.22 ± 0.31
  after bimatoprost 8.1 ± 0.5 1.7 ± 0.1 0.79 ± 0.02 1.90 ± 0.10
SPCA before bimatoprost 8.0 ± 1.1 1.9 ± 0.1 0.71 ± 0.03 1.61 ± 0.15
  after bimatoprost 10.1 ± 1.2 2.8 ± 0.4 0.75 ± 0.01 1.66 ± 0.05
LPCA before bimatoprost 14.8 ± 3.0 3.0 ± 0.7 0.78 ± 0.03 1.90 ± 0.17
  after bimatoprost 16.8 ± 2.2 3.0 ± 0.3 0.80 ± 0.02 1.90 ± 0.12
  1. Abbreviations: OA – Ophthalmic artery, CRA – central retinal artery, SPCA – short posterior ciliary artery, LPCA – long posterior ciliary artery, PSV – peak systolic velocity, EDV – enddiastolic velocity, RI – resistive index, PI – pulsatility index.