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Table 4 Multiple logistic regression analyses of cardiovascular risk factors and risk of AMD progression adjusted for age, APOE4 status and having ever smoked.

From: Novel measures of cardiovascular health and its association with prevalence and progression of age-related macular degeneration: the CHARM study

Cardiovascular risk factor

Number (%) of cases

Odds ratio

95% CL

Systemic arterial compliance

   

   Quartile 1

18 (21.7%)

1.0

 

   Quartile 2

20 (25.2%)

1.18

0.53, 2.61

   Quartile 3

18 (21.7%)

1.13

0.50, 2.55

   Quartile 4

23 (27.7%)

1.80

0.80, 4.04

Augmentation index

   

   Quartile 1

30 (38.4%)

1.0

 

   Quartile 2

21 (26.9%)

0.54

0.26, 1.16

   Quartile 3

14 (17.9%)

0.31

0.14, 0.70

   Quartile 4

13 (16.7%)

0.30

0.13, 0.69

Pulse wave velocity (aortic)*

   

   Quartile 1

7 (9.1%)

1.0

 

   Quartile 2

26 (33.8%)

6.22

2.35, 16.46

   Quartile 3

21 (27.3%)

3.69

1.38, 9.89

   Quartile 4

23 (29.9%)

3.36

1.24, 9.06

Mean maximum IMT

   

   Quartile 1

14 (17.1%)

1.0

 

   Quartile 2

19 (23.2%)

1.26

0.54, 2.92

   Quartile 3

25 (30.5%)

1.77

0.78, 4.01

   Quartile 4

24 (29.3%)

1.34

0.57, 3.17

  1. *p for linear trend = 0.008, **p for linear trend = 0.04
  2. (significant factors in bold)